Drug & supplement interaction

Iporuru + Sucralfate

Sucralfate brand names: Carafate, Antepsin.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Iporuru and Sucralfate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Sucralfate states a food rule worth keeping to.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Iporuru and Sucralfate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Sucralfate and Iporuru in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Iporuru at all — not against Sucralfate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Iporuru safety at a glance

Iporuru overall Not established There is little quality safety research on Iporuru in humans.
Pregnancy Avoid Safety is not established, so it is best avoided during pregnancy.
Breastfeeding Avoid There is no reliable safety data, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Sucralfate and Iporuru? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Sucralfate’s Own FDA Label Lists

This is not an interaction — none of it involves Iporuru. These are the most notable effects listed in the ADVERSE REACTIONS section of Sucralfate’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 4 of them are worth acting on rather than waiting out — marked below.

  • Wheezing Worth acting on
  • Shortness of breath Worth acting on
  • Hives Worth acting on
  • An allergic reaction Worth acting on
  • Bloating or gas
  • Dry mouth
  • Back pain
  • Drowsiness
  • Trouble sleeping
  • Stomach upset

Showing the 10 most notable of 19 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Sucralfate. Read the label on DailyMed › Iporuru’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Iporuru side to compare — that is a limit of the record, not a statement that Iporuru has no side effects.

How to take them

Some Sucralfate Products Have a Food Rule — Iporuru Should Not Break It

At least one FDA label for a product containing Sucralfate says to take it on an empty stomach. Most supplements — Iporuru included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Sucralfate on its own and move Iporuru to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Sucralfate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

D O S A G E A N D A D M INI S T R A T I O N A cti v e D u oden a l Ulc e r : The recommended adult oral dosage for duodenal ulcer is 1 g four times per day on an empty stomach.

From the Dosage and Administration section of the FDA label we read for Sucralfate — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Iporuru or Sucralfate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Iporuru or Sucralfate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Sucralfate

This page covers Iporuru only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Sucralfate page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Sucralfate page

“If you take sucralfate (Carafate) to heal an ulcer, keep activated charcoal well away from it. Charcoal carries the sole major rating on this list because it adsorbs drugs in the digestive tract, and sucralfate works entirely there, forming a protective coating over damaged stomach lining rather than circulating through the body.”

Reviewed by 2 · Jul 18, 2026

Open the Sucralfate interaction page

One more smart check

Taking Iporuru as Part of a Dietary Supplement Product? Check It for Interactions

We hold 5 real supplement products containing Iporuru, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Iporuru. Even though Iporuru itself has no known interaction with Sucralfate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Iporuru and Sucralfate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Iporuru
Top half

#666 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Sucralfate
Top 25%

#645 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Iporuru is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Iporuru reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Iporuru and Sucralfate records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Iporuru

What is Iporuru?

  • Joint and muscle pain
  • Arthritis and inflammation
  • Rheumatism
  • General aches and pains
  • Digestive complaints

Iporuru is an Amazonian shrub traditionally used by Indigenous peoples for joint pain, arthritis, and inflammation. Scientific evidence in humans is very limited, so its true benefits and safety are not well established. Talk with your pharmacist or doctor before using it, especially if you take other medicines or have health conditions.

Alchornea castaneifolia · Euphorbiaceae · Bark and leaves · Tea, tincture, capsules, dried bark

An interaction check asks whether these two react with each other — it does not ask whether Iporuru is a good idea for someone in your situation. Here is what our Iporuru record says about it on its own.

Iporuru: dosing

There is no established or standardized dose for Iporuru. Traditional preparations vary, and supplement labels differ from one product to another.If you choose to use it, follow the directions on the product label and do not exceed the recommended amount.

From our Iporuru monograph — the full record covers uses, side effects and every documented interaction.

Read the full Iporuru monograph & all interactions
Medication

About Sucralfate

What Is Sucralfate Used For?

Brand names: Carafate, Antepsin

Sucralfate — available as tablets and oral suspension under brand names including Carafate — is used for the short-term treatment (up to 8 weeks) of active duodenal ulcers.

Carafate tablets and sucralfate tablets are also approved for maintenance therapy — meaning a lower dose taken after an ulcer heals to help keep it from coming back.

Most-Reported Side Effects for Sucralfate

From FAERS, the FDA’s public side-effect reporting system (23,819 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 2,353 reports
Fatigue 1,798 reports
Diarrhea 1,764 reports
Headache 1,429 reports
Vomiting 1,411 reports
See full Sucralfate drug information
Keep checking

Other Drugs & Iporuru

Browse every other medication we’ve checked against Iporuru — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Iporuru against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Iporuru list.

See the full Iporuru interactions page
See every supplement checked against Sucralfate, ranked by severity
Evidence & sources

Iporuru References

The 3 sources that drive our Iporuru monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Iporuru is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Herbs at a Glance — NIH NCCIH Source
  3. Herbal Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Iporuru and Sucralfate Together: Common Questions

Is it safe to take Iporuru with Sucralfate?
We do not list a known interaction between Iporuru and Sucralfate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Iporuru and Sucralfate at the same time of day?
At least one FDA label for a product containing Sucralfate says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Sucralfate on its own and move Iporuru to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Sucralfate interact with any supplements?
Yes. Sucralfate has documented interactions with 17 supplements in our database — Iporuru is not one of them. The Sucralfate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Iporuru monograph Uses, safety profile, and every drug interaction in one place Sucralfate drug information The full plain-English guide to this medication Sucralfate supplement interactions Every supplement checked against Sucralfate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Sucralfate and Iporuru?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.