Drug & supplement interaction

Javanese Turmeric + Lesinurad

Lesinurad brand name: Zurampic.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Javanese Turmeric and Lesinurad in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Javanese Turmeric and Lesinurad

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lesinurad and Javanese Turmeric in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Javanese Turmeric safety at a glance

Javanese Turmeric overall Use caution Generally well tolerated in food-like amounts, but human safety data for concentrated supplements are limited.
Pregnancy Avoid Not enough safety data, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoiding it is the safer choice.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lesinurad and Javanese Turmeric? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Lesinurad

Interactions in our licensed database are recorded against drug classes, not just single drug names. Lesinurad is filed under 4 classifications — including antigout drugs, cytochrome p450 3a4 (cyp3a4) inducers, cytochrome p450 2c9 (cyp2c9) substrates. Javanese Turmeric has documented interactions with 1 drug class — the most serious being warfarin (coumadin) (moderate) — and none of Lesinurad’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Javanese Turmeric Does Interact With Other Medications

Javanese Turmeric has 2 moderate known drug interactions in our database — Lesinurad isn’t one of them. If you take anything else, check it against the full list below.

Moderate 2 No known interaction 2,828 (incl. Lesinurad)
Taking anything else?

Check Another of Your Medications Against Javanese Turmeric

Covers the 2,830 medications we’ve checked against Javanese Turmeric. Pick one to open its full report.

What to actually watch for

What Javanese Turmeric Itself Has Been Linked To

This is not an interaction — nothing below involves Lesinurad. It is the side-effect record for Javanese Turmeric on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Javanese Turmeric, this list is the first place to look.

  • Stomach upset / Nausea Additional detail

    “Orally, Javanese turmeric can cause gastric irritation and nausea when used in large amounts or for prolonged periods of time (2,8).”

    Javanese Turmeric · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    2 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 8. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.

Everything above comes from the Natural Medicines adverse-effect record for Javanese Turmeric — expand a row for the licensed statement it rests on. We haven’t matched Lesinurad to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Lesinurad.

Everything else you take

See Every Supplement That Interacts With Lesinurad

This page covers Javanese Turmeric only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lesinurad page lists 97 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Adrafinil (moderate), African Wild Potato (moderate), Alkanna (moderate) and Alpine Ragwort (moderate).

By severity: 1 major · 74 moderate · 22 minor.

From our pharmacist’s overview on the Lesinurad page

“Activated charcoal is the one major-rated entry among the 97 supplements and herbs on file for lesinurad (Zurampic), and it undermines the drug directly. Charcoal binds medicines in the gut and can cut how much lesinurad you absorb, letting uric acid climb and gout flare.”

Reviewed by 2 · Jul 18, 2026

Open the Lesinurad interaction page

One more smart check

Taking Javanese Turmeric as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Javanese Turmeric, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Javanese Turmeric. Even though Javanese Turmeric itself has no known interaction with Lesinurad, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Javanese Turmeric and Lesinurad Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Javanese Turmeric
Steady interest

#1,001 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lesinurad
Top half

#1,398 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Javanese Turmeric reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Javanese Turmeric and Lesinurad records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Javanese Turmeric

What is Javanese Turmeric?

  • Digestive upset and bloating
  • Liver and gallbladder support
  • Loss of appetite
  • Joint and inflammation complaints
  • General wellness tonic

Javanese turmeric (Curcuma zanthorrhiza), known in Indonesia as temulawak, is a ginger-family root traditionally used for digestive and liver complaints. Early lab and animal studies are interesting, but strong human evidence is limited, so it should be viewed as a traditional remedy rather than a proven treatment. Talk to a pharmacist or doctor before using it, especially if you have a health condition or take medications.

Curcuma zanthorrhiza · Zingiberaceae · Rhizome (root) · Capsules, tablets, powder, dried root, tea, liquid extracts

An interaction check asks whether these two react with each other — it does not ask whether Javanese Turmeric is a good idea for someone in your situation. Here is what our Javanese Turmeric record says about it on its own.

Javanese Turmeric: dosing

There is no well-established standardized dose for Javanese turmeric. Products vary widely in strength and form, and the active compounds are absorbed differently from one preparation to another.The safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Javanese Turmeric monograph — the full record covers uses, side effects and every documented interaction.

Read the full Javanese Turmeric monograph & all interactions
Medication

About Lesinurad

What Is Lesinurad Used For?

Brand name: Zurampic

  • Lesinurad is used in combination with a xanthine oxidase inhibitor to treat hyperuricemia (high levels of uric acid) in people with gout (sudden attacks of redness, swelling, pain, and heat in one or more joints) whose disease is not controlled with their current medication. Lesinurad is in a class of medications called selective uric acid reabsorption inhibitors. It works by helping the kidneys to remove uric acid from the body.

See full Lesinurad drug information
Keep checking

Other Drugs & Javanese Turmeric

Browse every other medication we’ve checked against Javanese Turmeric — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
2Moderate
0Minor
2,827No known interaction
2 Moderate 2,827 No interaction
Moderate

2 interactions

No interaction 2,827 drugs checked — show the list

We also checked Javanese Turmeric against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,827 medications checked with no known interaction — see the full Javanese Turmeric list.

See the full Javanese Turmeric interactions page
See every supplement checked against Lesinurad, ranked by severity
Evidence & sources

Javanese Turmeric References

The 3 references that drive our Javanese Turmeric monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Rusdiana T, Mardhiani YD, Putriana NA, et al. The influence of Javanese turmeric (Curcuma xanthorrhiza) on the pharmacokinetics of warfarin in rats with single and multiple-dose studies. Pharm Biol. 2021;59(1):639-646.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Javanese Turmeric and Lesinurad Together: Common Questions

Is it safe to take Javanese Turmeric with Lesinurad?
We do not list a known interaction between Javanese Turmeric and Lesinurad. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Javanese Turmeric and Lesinurad combination checked?
Interactions in our licensed database are recorded against drug classes. Lesinurad is filed under 4 classifications, and Javanese Turmeric has documented interactions with 1 drug class — none of Lesinurad's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Javanese Turmeric interact with any other medications?
Yes. Javanese Turmeric has 2 documented drug interactions in our database — Lesinurad is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Lesinurad interact with any supplements?
Yes. Lesinurad has documented interactions with 97 supplements in our database — Javanese Turmeric is not one of them. The Lesinurad interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Javanese Turmeric monograph Uses, safety profile, and every drug interaction in one place Lesinurad drug information The full plain-English guide to this medication Lesinurad supplement interactions Every supplement checked against Lesinurad, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Lesinurad and Javanese Turmeric?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.