Drug & supplement interaction

Lactase + Flurandrenolide

Flurandrenolide brand name: Cordran.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Lactase and Flurandrenolide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Lactase and Flurandrenolide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Flurandrenolide and Lactase in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Lactase at all — not against Flurandrenolide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lactase safety at a glance

Lactase overall Generally safe Lactase is generally well tolerated when used as directed.
Pregnancy Likely Safe When used orally and appropriately with lactose-containing foods. Read the full pregnancy detail
Breastfeeding Likely Safe When used orally and appropriately with lactose-containing foods. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Flurandrenolide and Lactase? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Lactase and Flurandrenolide May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash reported in 5.5% of FDA reports for Flurandrenolide Additional detail

    Lactase

    “A case of lactase-induced contact dermatitis and immunoglobulin E (IgE)-mediated allergic rhinoconjunctivitis has been reported in a worker exposed to powdered lactase. Allergy to lactase was confirmed by prick test, open application test, and chamber challenge test.”

    Lactase · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    1 source cited
    1. 96348. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

    Flurandrenolide

    Listed in the ADVERSE REACTIONS section of the FDA label for Flurandrenolide, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Effects for Flurandrenolide come from the ADVERSE REACTIONS section of its FDA label; effects for Lactase come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 329 voluntary FDA FAERS reports for Flurandrenolide that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Lactase in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally and appropriately with lactose-containing foods.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Flurandrenolide

This page covers Lactase only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Flurandrenolide page lists 3 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).

By severity: 2 moderate · 1 minor.

From our pharmacist’s overview on the Flurandrenolide page

“DMSO is the risk to know about first. Applied to the same skin as flurandrenolide (Cordran), a prescription steroid cream for inflamed, itchy conditions like eczema and psoriasis, DMSO may pull more of the drug through the skin, amplifying its effects and its side effects alike.”

Reviewed by 2 · Jul 18, 2026

Open the Flurandrenolide interaction page

One more smart check

Taking Lactase as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3,200 real supplement products containing Lactase, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Lactase. Even though Lactase itself has no known interaction with Flurandrenolide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Lactase and Flurandrenolide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lactase
Top 10%

#91 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Flurandrenolide
Steady interest

#2,000 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lactase reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Lactase and Flurandrenolide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lactase

What is Lactase?

  • Lactose intolerance
  • Gas and bloating after dairy
  • Diarrhea from dairy foods
  • Stomach cramps from milk products

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhea when taken with dairy foods, and it is generally considered safe for most people. It treats symptoms only and does not cure lactose intolerance.

Enzyme (often sourced from yeast such as Kluyveromyces lactis or fungi like Aspergillus species) · Tablets, caplets, chewables, drops (liquid), and capsules

An interaction check asks whether these two react with each other — it does not ask whether Lactase is a good idea for someone in your situation. Here is what our Lactase record says about it on its own.

Lactase: dosing

There is no single official dose for lactase. The amount of enzyme is usually measured in FCC lactase units, and different products contain different strengths.In general, lactase is taken right before or with the first bite of a dairy-containing food or drink. With liquid drops, you can add them to milk and let it sit as directed on the label. Start with the smallest amount that controls your symptoms.

From our Lactase monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lactase monograph & all interactions
Medication

About Flurandrenolide Topical

What Is Flurandrenolide Topical Used For?

Brand name: Cordran

Flurandrenolide topical is used to treat the inflammation and itching that come with corticosteroid-responsive dermatoses — a broad term for skin conditions that respond to steroid treatment, such as eczema, psoriasis, and allergic skin reactions.

Cordran is used to relieve these inflammatory and itchy skin manifestations. Occlusive dressings (airtight coverings over the medication) may be used with Cordran for hard-to-treat conditions like psoriasis.

Most-Reported Side Effects for Flurandrenolide

From FAERS, the FDA’s public side-effect reporting system (329 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Pruritus 31 reports
Nausea 20 reports
Fatigue 18 reports
Headache 18 reports
Rash 18 reports
See full Flurandrenolide Topical drug information
Keep checking

Other Drugs & Lactase

Browse every other medication we’ve checked against Lactase — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Lactase against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Lactase list.

See the full Lactase interactions page
See every supplement checked against Flurandrenolide, ranked by severity
Evidence & sources

Lactase References

The 1 references that drive our Lactase monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lactase and Flurandrenolide Together: Common Questions

Is it safe to take Lactase with Flurandrenolide?
We do not list a known interaction between Lactase and Flurandrenolide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Lactase and Flurandrenolide have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Flurandrenolide interact with any supplements?
Yes. Flurandrenolide has documented interactions with 3 supplements in our database — Lactase is not one of them. The Flurandrenolide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Lactase monograph Uses, safety profile, and every drug interaction in one place Flurandrenolide Topical drug information The full plain-English guide to this medication Flurandrenolide supplement interactions Every supplement checked against Flurandrenolide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Flurandrenolide and Lactase?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.