Drug & supplement interaction

Laurelwood + Obinutuzumab

Obinutuzumab brand name: Gazyva.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Laurelwood and Obinutuzumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Obinutuzumab states a food rule worth keeping to.

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Interaction report

Laurelwood and Obinutuzumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Obinutuzumab and Laurelwood in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Laurelwood at all — not against Obinutuzumab, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Laurelwood safety at a glance

Laurelwood overall Use caution Generally used on the skin only; it can cause allergic reactions and should not be swallowed.
Pregnancy Use caution Limited safety data; topical use may be acceptable but check with your doctor first.
Breastfeeding Use caution Not enough reliable information, so use caution and keep it off the nipple area if nursing.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Obinutuzumab and Laurelwood? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Laurelwood Itself Has Been Linked To

This is not an interaction — nothing below involves Obinutuzumab. It is the side-effect record for Laurelwood on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Laurelwood, this list is the first place to look.

  • Dizziness / Headache Additional detail

    “There is currently a limited amount of information available about the adverse effects of laurelwood. Orally, calanolide A, a constituent of laurelwood, has been reported to cause an oily aftertaste, nausea, dizziness, and headache. Topically, tamanu oil from the laurelwood nut has been reported to cause allergic contact dermatitis.”

    Laurelwood · Natural Medicines adverse-effect record, reported in cluster headache.

    2 sources cited
    1. 4290. Reuters Health. Anti-HIV herbal product shows therapeutic potential in phase I trial. November 1, 1999.
    2. 76959. Oku, H., Ueda, Y., Iinuma, M., and Ishiguro, K. Inhibitory effects of xanthones from guttiferae plants on PAF-induced hypotension in mice. Planta Med 2005;71(1):90-92. PubMed

    “Orally, the use of calanolide A, a laurelwood constituent, can cause dizziness and headache.”

    Laurelwood · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 4290. Reuters Health. Anti-HIV herbal product shows therapeutic potential in phase I trial. November 1, 1999.
  • A skin rash Additional detail

    “Topically, there is one case report of allergic contact dermatitis related to the use of tamanu oil from the nut of laurelwood.”

    Laurelwood · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 76958. Le Coz, C. J. Allergic contact dermatitis from tamanu oil (Calophyllum inophyllum, Calophyllum tacamahaca). Contact Dermatitis 2004;51(4):216-217. PubMed
  • Nausea Additional detail

    “Orally, the use of calanolide A, a laurelwood constituent, can cause an oily aftertaste and nausea.”

    Laurelwood · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 4290. Reuters Health. Anti-HIV herbal product shows therapeutic potential in phase I trial. November 1, 1999.

Everything above comes from the Natural Medicines adverse-effect record for Laurelwood — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Obinutuzumab’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Obinutuzumab column appears here.

How to take them

Some Obinutuzumab Products Have a Food Rule — Laurelwood Should Not Break It

At least one FDA label for a product containing Obinutuzumab says to take it on an empty stomach. Most supplements — Laurelwood included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Obinutuzumab on its own and move Laurelwood to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Obinutuzumab products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

650–1,000 mg acetaminophen At least 30 minutes before GAZYVA infusion.

From the Dosage and Administration section of the FDA label we read for Obinutuzumab — where that label names a specific product, the instruction is that product's. See the Obinutuzumab drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

How much people look this up

Where Laurelwood and Obinutuzumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Laurelwood
Steady interest

#1,174 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Obinutuzumab
Steady interest

#1,800 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Laurelwood reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Laurelwood and Obinutuzumab records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Laurelwood

What is Laurelwood?

  • Skin care and moisturizing
  • Minor wounds and scars
  • Acne-prone skin
  • Dry or irritated skin
  • Soothing minor burns or insect bites

Laurelwood, the source of tamanu oil, is a tropical tree whose seed oil is used mainly on the skin for moisturizing, soothing irritation, and supporting wound healing. Most evidence is preliminary or based on laboratory studies, and it is meant for external use only. Talk to a pharmacist or doctor before using it, and avoid swallowing the oil.

Calophyllum inophyllum · Calophyllaceae · Seeds (pressed into oil), and at times the bark and leaves · Tamanu oil (cold-pressed seed oil), creams, balms, and topical skincare products

An interaction check asks whether these two react with each other — it does not ask whether Laurelwood is a good idea for someone in your situation. Here is what our Laurelwood record says about it on its own.

Laurelwood: dosing

There is no official or standardized dose for laurelwood (tamanu) oil. It is used topically, and the amount depends on the product and the area being treated.The safest approach is to follow the directions on the product label and to start with a small amount on a small area.

From our Laurelwood monograph — the full record covers uses, side effects and every documented interaction.

Read the full Laurelwood monograph & all interactions
Medication

About Obinutuzumab Injection

What Is Obinutuzumab Injection Used For?

Brand name: Gazyva

Gazyva is used to treat three conditions. For chronic lymphocytic leukemia (CLL), it is given in combination with chlorambucil in patients who have not been treated before. For follicular lymphoma (FL), it is used either with bendamustine (for patients whose disease came back or stopped responding to a rituximab-based regimen) or with chemotherapy (for previously untreated advanced disease) — in both cases followed by Gazyva alone as maintenance therapy.

Gazyva is also approved for active lupus nephritis — a type of kidney inflammation caused by lupus — in adults who are already receiving standard therapy for the condition.

See full Obinutuzumab Injection drug information
Keep checking

Other Drugs & Laurelwood

Browse every other medication we’ve checked against Laurelwood — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Laurelwood against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Laurelwood list.

See the full Laurelwood interactions page
See every supplement checked against Obinutuzumab, ranked by severity
Evidence & sources

Laurelwood References

The 3 references that drive our Laurelwood monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Reuters Health. Anti-HIV herbal product shows therapeutic potential in phase I trial. November 1, 1999.
  2. Le Coz, C. J. Allergic contact dermatitis from tamanu oil (Calophyllum inophyllum, Calophyllum tacamahaca). Contact Dermatitis 2004;51(4):216-217. PubMed
  3. Oku, H., Ueda, Y., Iinuma, M., and Ishiguro, K. Inhibitory effects of xanthones from guttiferae plants on PAF-induced hypotension in mice. Planta Med 2005;71(1):90-92. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Laurelwood and Obinutuzumab Together: Common Questions

Is it safe to take Laurelwood with Obinutuzumab?
We do not list a known interaction between Laurelwood and Obinutuzumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Laurelwood and Obinutuzumab at the same time of day?
At least one FDA label for a product containing Obinutuzumab says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Obinutuzumab on its own and move Laurelwood to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Laurelwood monograph Uses, safety profile, and every drug interaction in one place Obinutuzumab Injection drug information The full plain-English guide to this medication Obinutuzumab supplement interactions Every supplement checked against Obinutuzumab, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Obinutuzumab and Laurelwood?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.