Drug & supplement interaction

Liver Extract + Alectinib Hydrochloride

Alectinib Hydrochloride brand name: Alecensa.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Liver Extract and Alectinib Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Alectinib Hydrochloride states a food rule worth keeping to.

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Interaction report

Liver Extract and Alectinib Hydrochloride

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Alectinib Hydrochloride and Liver Extract in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Liver Extract safety at a glance

Liver Extract overall Use caution Generally low risk for healthy adults in food amounts, but it can deliver high levels of vitamin A and iron and carries source-quality concerns.
Pregnancy Use caution Liver products can contain very high vitamin A, which may harm a developing baby, so avoid unless advised by your doctor.
Breastfeeding Use caution Safety has not been well studied; check with your doctor before using.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Alectinib Hydrochloride and Liver Extract? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Alectinib Hydrochloride

Interactions in our licensed database are recorded against drug classes, not just single drug names. Alectinib Hydrochloride is filed under 3 classifications — photosensitizing drugs, hepatotoxic drugs, oral drugs. Liver Extract has documented interactions with 2 drug classes — the most serious being iron (minor) and warfarin (coumadin) (minor) — and none of Alectinib Hydrochloride’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Liver Extract Does Interact With Other Medications

Liver Extract has 3 minor known drug interactions in our database — Alectinib Hydrochloride isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Liver Extract

Covers the 2,830 medications we’ve checked against Liver Extract. Pick one to open its full report.

What to actually watch for

What Alectinib Hydrochloride’s Own FDA Label Lists

This is not an interaction — none of it involves Liver Extract. These are the most notable effects listed in the ADVERSE REACTIONS section of Alectinib Hydrochloride’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Muscle weakness Worth acting on
  • High potassium Worth acting on
  • Low sodium Worth acting on
  • Low potassium Worth acting on
  • A slow heartbeat Worth acting on
  • A heart attack Worth acting on
  • Blood clots Worth acting on
  • Pancreatitis Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • High blood sugar Worth acting on

Showing the 10 most notable of 39 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Alectinib Hydrochloride. Read the label on DailyMed › Where a percentage is shown, it is the share of 7,249 voluntary FDA FAERS reports for Alectinib Hydrochloride that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Liver Extract’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Liver Extract side to compare — that is a limit of the record, not a statement that Liver Extract has no side effects.

How to take them

Some Alectinib Hydrochloride Products Have a Food Rule — Liver Extract Should Not Break It

At least one FDA label for a product containing Alectinib Hydrochloride says to take it with food. If you take Liver Extract on an empty stomach out of habit, keep them separate — and take Alectinib Hydrochloride with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Alectinib Hydrochloride products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Administer ALECENSA with food.

From the Dosage and Administration section of the FDA label we read for Alectinib Hydrochloride — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Alectinib Hydrochloride

This page covers Liver Extract only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Alectinib Hydrochloride page lists 74 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Siberian Cocklebur (major), Wine (major) and Alfalfa (moderate).

By severity: 4 major · 60 moderate · 10 minor.

From our pharmacist’s overview on the Alectinib Hydrochloride page

“Alectinib (Alecensa) treats ALK-positive lung cancer, and because your liver already has to tolerate this drug, check this page before adding any supplement, not after. Of the 74 ingredients on file, 38 can add stress to the liver, and three of the four major-rated entries (beer, wine, and Siberian cocklebur) are the clearest examples…”

Reviewed by 2 · Jul 18, 2026

Open the Alectinib Hydrochloride interaction page

One more smart check

Taking Liver Extract as Part of a Dietary Supplement Product? Check It for Interactions

We hold 595 real supplement products containing Liver Extract, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Liver Extract. Even though Liver Extract itself has no known interaction with Alectinib Hydrochloride, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Liver Extract and Alectinib Hydrochloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Liver Extract
Top 25%

#273 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Alectinib Hydrochloride
Steady interest

#1,995 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Liver Extract reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Liver Extract and Alectinib Hydrochloride records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Liver Extract

What is Liver Extract?

  • Anemia and low iron
  • Vitamin B12 support
  • General energy and fatigue
  • Nutritional support for athletes
  • Liver health support

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once used to treat certain anemias before purified vitamins became available, but today there is little modern evidence that it offers benefits beyond what a balanced diet or standard supplements provide. Talk with your pharmacist or doctor before using it, especially if you are pregnant, have liver disease, or have iron overload conditions.

Liver tissue, usually from cattle (beef) or pork · Capsules, tablets, powders, desiccated (dried) liver supplements, and injectable forms (prescription/historical)

An interaction check asks whether these two react with each other — it does not ask whether Liver Extract is a good idea for someone in your situation. Here is what our Liver Extract record says about it on its own.

Liver Extract: dosing

There is no official, standardized dose of liver extract, and products vary widely in how concentrated they are. Different brands also contain different amounts of vitamin A, iron, and B12.The safest approach is to follow the dose on the product label and not exceed it. They can help you decide whether you actually need it and whether a standard, purified vitamin would be a safer, more reliable choice.

From our Liver Extract monograph — the full record covers uses, side effects and every documented interaction.

Read the full Liver Extract monograph & all interactions
Medication

About Alectinib

What Is Alectinib Used For?

Brand name: Alecensa

Alecensa (alectinib) is used in adults with non-small cell lung cancer (NSCLC) whose tumors have a specific genetic change called ALK-positive (anaplastic lymphoma kinase-positive), confirmed by an FDA-approved test.

Alecensa is used in two situations: as adjuvant treatment — meaning after surgical removal of the tumor — in patients whose tumors were at least 4 cm or had spread to nearby lymph nodes; and as treatment for metastatic NSCLC, meaning cancer that has spread to other parts of the body.

Most-Reported Side Effects for Alectinib Hydrochloride

From FAERS, the FDA’s public side-effect reporting system (7,249 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 518 reports
Constipation 445 reports
Rash 257 reports
Dyspnea 234 reports
Disease progression 210 reports
See full Alectinib drug information
Keep checking

Other Drugs & Liver Extract

Browse every other medication we’ve checked against Liver Extract — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
3Minor
2,826No known interaction
Minor

3 interactions

No interaction 2,826 drugs checked — show the list
Evidence & sources

Liver Extract References

The 4 references that drive our Liver Extract monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Liver Extract and Alectinib Hydrochloride Together: Common Questions

Is it safe to take Liver Extract with Alectinib Hydrochloride?
We do not list a known interaction between Liver Extract and Alectinib Hydrochloride. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Liver Extract and Alectinib Hydrochloride at the same time of day?
At least one FDA label for a product containing Alectinib Hydrochloride says to take it with food. If you take Liver Extract on an empty stomach out of habit, keep them separate and take Alectinib Hydrochloride with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Alectinib Hydrochloride products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Liver Extract and Alectinib Hydrochloride combination checked?
Interactions in our licensed database are recorded against drug classes. Alectinib Hydrochloride is filed under 3 classifications, and Liver Extract has documented interactions with 2 drug classes — none of Alectinib Hydrochloride's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Liver Extract interact with any other medications?
Yes. Liver Extract has 3 documented drug interactions in our database — Alectinib Hydrochloride is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Alectinib Hydrochloride interact with any supplements?
Yes. Alectinib Hydrochloride has documented interactions with 74 supplements in our database — Liver Extract is not one of them. The Alectinib Hydrochloride interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Alectinib Hydrochloride and Liver Extract?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.