Drug & supplement interaction

Lotus + Immune Globulin, Gamma Globulin

Immune Globulin, Gamma Globulin brand name: BayGam.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 13, 2026

The bottom line No known interaction

We found no known interaction between Lotus and Immune Globulin, Gamma Globulin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Lotus and Immune Globulin, Gamma Globulin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Immune Globulin, Gamma Globulin and Lotus in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lotus safety at a glance

Lotus overall Use caution Common as a food, but supplement safety has not been well studied in humans.

Pregnancy Avoid Not enough safety data for medicinal amounts, so avoid concentrated supplements.

Breastfeeding Avoid Safety has not been established, so avoid supplement use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Immune Globulin, Gamma Globulin and Lotus? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

Keep it in perspective

Lotus Does Interact With Other Medications

Lotus has 212 moderate known drug interactions in our database — Immune Globulin, Gamma Globulin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 212 No known interaction 2,618 (incl. Immune Globulin, Gamma Globulin)

Taking anything else?

Check Another of Your Medications Against Lotus

Covers the 2,830 medications we’ve checked against Lotus. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Lotus and Immune Globulin, Gamma Globulin May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 2 of them are worth acting on rather than waiting out — marked below.

Hives / An allergic reaction Worth acting on Additional detail
Lotus
“Orally and topically, lotus root can cause allergic reactions such as urticaria and contact dermatitis. In a case report, a 6-year-old female developed urticaria after ingesting lotus root. She had also developed contact dermatitis on body areas that had been in contact with the lotus root.”

Lotus · Natural Medicines adverse-effect record, reported in dermatitis.
1 source cited

99738. Hiraguchi Y, Tokuda R, Gen M, et al. Identification of a novel food allergen in lotus root. Allergol Int. 2018;67(1):141-143. PubMed
Immune Globulin, Gamma Globulin

Listed in the ADVERSE REACTIONS section of the FDA label for Immune Globulin, Gamma Globulin. Read the label on DailyMed ›
A skin rash Additional detail

Lotus

Recorded for Lotus in the same Natural Medicines adverse-effect record shown under Hives / An allergic reaction above.

Immune Globulin, Gamma Globulin

Listed in the ADVERSE REACTIONS section of the FDA label for Immune Globulin, Gamma Globulin. Read the label on DailyMed ›

Effects for Immune Globulin, Gamma Globulin come from the ADVERSE REACTIONS section of its FDA label; effects for Lotus come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

One more smart check

Taking Lotus as Part of a Dietary Supplement Product? Check It for Interactions

We hold 256 real supplement products containing Lotus, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Lotus. Even though Lotus itself has no known interaction with Immune Globulin, Gamma Globulin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Lotus and Immune Globulin, Gamma Globulin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lotus

Top half

#425 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Immune Globulin, Gamma Globulin

Top 25%

#401 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lotus reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Lotus and Immune Globulin, Gamma Globulin records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Lotus

What is Lotus?

Digestive upset and diarrhea
Anxiety and relaxation
Sleep support
Blood sugar and cholesterol support
Skin and general wellness

Lotus is an edible aquatic plant used in food and traditional medicine across Asia, with parts like the seeds, leaves, and flowers taken for digestion, calm, and overall wellness. Most health claims come from laboratory and animal research rather than strong human studies, so its benefits as a supplement are not well proven. Eating lotus as food is generally safe, but talk to your pharmacist or doctor before using concentrated supplements, especially if you are pregnant, breastfeeding, or taking other medicines.

Nelumbo nucifera · Nelumbonaceae · Seeds, leaves, flowers, rhizome (root), and stamens · Tea, capsules, powders, dried seeds, extracts, and culinary foods

An interaction check asks whether these two react with each other — it does not ask whether Lotus is a good idea for someone in your situation. Here is what our Lotus record says about it on its own.

Lotus: dosing

There is no standardized or officially established dose for lotus supplements. The right amount depends on the part of the plant used, the form, and how concentrated the product is.The safest approach is to follow the directions on the product label and not exceed them. Because human research is limited, no proven "effective dose" exists.

From our Lotus monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lotus monograph & all interactions

Keep checking

Other Drugs & Lotus

Browse every other medication we’ve checked against Lotus — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

212Moderate

0Minor

2,617No known interaction

212 Moderate 2,617 No interaction

Moderate

212 interactions

Showing 60 of 212 moderate interactions — see all 212 on the Lotus page.

No interaction 2,617 drugs checked — show the list

We also checked Lotus against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,617 medications checked with no known interaction — see the full Lotus list.

See the full Lotus interactions page

See every supplement checked against Immune Globulin, Gamma Globulin, ranked by severity

Evidence & sources

Lotus References

The 5 references that drive our Lotus monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Yu, J. and Hu, W. S. [Effects of neferine on platelet aggregation in rabbits]. Yao Xue.Xue.Bao. 1997;32(1):1-4.
Yang, J. and Zhou, K. NMR spectroscopic analysis of neferine and isoliensinine. Magn Reson.Chem 2004;42(11):994-997. PubMed
Mukherjee, P. K., Saha, K., Balasubramanian, R., Pal, M., and Saha, B. P. Studies on psychopharmacological effects of Nelumbo nucifera Gaertn. rhizome extract. J Ethnopharmacol. 1996;54(2-3):63-67. PubMed
Mukherjee, P. K., Saha, K., Pal, M., and Saha, B. P. Effect of Nelumbo nucifera rhizome extract on blood sugar level in rats. J Ethnopharmacol. 1997;58(3):207-213. PubMed
Hiraguchi Y, Tokuda R, Gen M, et al. Identification of a novel food allergen in lotus root. Allergol Int. 2018;67(1):141-143. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lotus and Immune Globulin, Gamma Globulin Together: Common Questions

Is it safe to take Lotus with Immune Globulin, Gamma Globulin?

We do not list a known interaction between Lotus and Immune Globulin, Gamma Globulin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Do Lotus and Immune Globulin, Gamma Globulin have any of the same side effects?

Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.

Does Lotus interact with any other medications?

Yes. Lotus has 212 documented drug interactions in our database — Immune Globulin, Gamma Globulin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Lotus monograph Uses, safety profile, and every drug interaction in one place Immune Globulin, Gamma Globulin supplement interactions Every supplement checked against Immune Globulin, Gamma Globulin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 5 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Immune Globulin, Gamma Globulin and Lotus?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.