Drug & supplement interaction

Low Purine Diet + Dantrolene

Dantrolene brand names: Dantrium, Dantrium Intravenous.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Low Purine Diet and Dantrolene in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Low Purine Diet and Dantrolene

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dantrolene and Low Purine Diet in our sources. This does not guarantee that the combination is completely free of risk — research on Low Purine Diet alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Low Purine Diet at all — not against Dantrolene, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Low Purine Diet is an eating pattern rather than something you take. Ask your pharmacist or doctor before changing how you eat while on a prescribed medicine: some medicines are dosed around meals, and a change in diet can change how they work. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Low Purine Diet safety at a glance

Low Purine Diet overall Generally safe A balanced low purine diet is generally safe for most healthy adults.
Pregnancy Use caution Generally safe but get guidance to ensure adequate nutrition during pregnancy.
Breastfeeding Use caution Generally safe but ensure balanced nutrition; talk to your doctor or dietitian.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dantrolene and Low Purine Diet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Dantrolene’s Own FDA Label Lists

This is not an interaction — none of it involves Low Purine Diet. These are the most notable effects listed in the ADVERSE REACTIONS section of Dantrolene’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you follow Low Purine Diet and take the medicine. 8 of them are worth acting on rather than waiting out — marked below.

  • Muscle weakness Worth acting on
  • Trouble swallowing Worth acting on
  • Blood clots Worth acting on
  • An irregular heartbeat Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • Liver problems Worth acting on
  • An allergic reaction Worth acting on
  • Pain in an arm or leg
  • Flushing

Showing the 10 most notable of 19 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Dantrolene. Read the label on DailyMed › Low Purine Diet’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Low Purine Diet side to compare — that is a limit of the record, not a statement that Low Purine Diet has no side effects.

Everything else you take

See Every Supplement That Interacts With Dantrolene

This page covers Low Purine Diet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dantrolene page lists 77 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Procaine (major), Siberian Cocklebur (major) and Wine (major).

By severity: 5 major · 62 moderate · 10 minor.

From our pharmacist’s overview on the Dantrolene page

“People take dantrolene (Dantrium) for muscle spasticity from multiple sclerosis or spinal cord injury, and the drug already carries a boxed warning for liver injury. That is why its supplement interactions deserve genuine respect.”

Reviewed by 2 · Jul 18, 2026

Open the Dantrolene interaction page

How much people look this up

Where Low Purine Diet and Dantrolene Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Low Purine Diet
Steady interest

#1,334 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dantrolene
Steady interest

#2,346 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Low Purine Diet is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Low Purine Diet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Low Purine Diet and Dantrolene records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Eating pattern

About Low Purine Diet

What is Low Purine Diet?

  • Gout management
  • Lowering uric acid levels
  • Preventing kidney stones (uric acid stones)
  • Reducing gout flare-ups

A low purine diet is an eating plan that limits foods high in purines, which the body breaks down into uric acid. It is mainly used to help manage gout and certain kidney stones, often alongside medication. While it can lower uric acid somewhat, diet alone usually is not enough for most people with gout, so work with your doctor on a full treatment plan.

Dietary pattern (meal plan), not a supplement

An interaction check asks whether these two react with each other — it does not ask whether Low Purine Diet is a good idea for someone in your situation. Here is what our Low Purine Diet record says about it on its own.

Low Purine Diet: dosing

There is no fixed "dose" for a low purine diet because it is an eating pattern, not a pill. In general, the goal is to limit high-purine foods (organ meats, red meat, certain seafood, beer, and sugary drinks) while eating more vegetables, fruits, whole grains, and low-fat dairy.Drinking plenty of water and limiting alcohol are also key parts of the plan.

From our Low Purine Diet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Low Purine Diet monograph & all interactions
Medication

About Dantrolene

What Is Dantrolene Used For?

Brand names: Dantrium, Dantrium Intravenous

Dantrolene sodium capsules (Dantrium, Dantrolene Sodium) are used by mouth to control spasticity — painful or disabling muscle stiffness and spasms — caused by upper motor neuron disorders such as spinal cord injury, stroke, cerebral palsy, or multiple sclerosis. They are not used for muscle spasm from arthritis or other rheumatic conditions. Oral capsules are also used before and after surgery to prevent or reduce the risk of malignant hyperthermia in patients known to be susceptible.

For an active malignant hyperthermia crisis — a sudden, dangerous overheating of the muscles triggered by certain anesthetics — the intravenous (IV) forms are given in the hospital. Dantrium Intravenous, Revonto, Ryanodex, and Dantrolene injection are all indicated to treat a malignant hyperthermia crisis and may also be given before surgery to help prevent one in high-risk patients.

See full Dantrolene drug information
Keep checking

Other Drugs & Low Purine Diet

Browse every other medication we’ve checked against Low Purine Diet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Low Purine Diet against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Low Purine Diet list.

See the full Low Purine Diet interactions page
See every supplement checked against Dantrolene, ranked by severity
Evidence & sources

Low Purine Diet References

The 2 sources that drive our Low Purine Diet monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Low Purine Diet is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Gout — MedlinePlus Source
  2. Gout — Cleveland Clinic Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Following Low Purine Diet While Taking Dantrolene: Common Questions

Is it safe to follow Low Purine Diet while taking Dantrolene?
We do not list a known interaction between Low Purine Diet and Dantrolene. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Dantrolene interact with any supplements?
Yes. Dantrolene has documented interactions with 77 supplements in our database — Low Purine Diet is not one of them. The Dantrolene interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Low Purine Diet monograph Uses, safety profile, and every drug interaction in one place Dantrolene drug information The full plain-English guide to this medication Dantrolene supplement interactions Every supplement checked against Dantrolene, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Dantrolene and Low Purine Diet?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.