Drug & supplement interaction

Methyldiazinol + Nitroglycerin

Nitroglycerin brand names: Nitrostat, Nitrogard SR, Sustachron, Nitro-Bid, Sustachron ER Buccal, and others.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Methyldiazinol and Nitroglycerin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Methyldiazinol and Nitroglycerin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Nitroglycerin and Methyldiazinol in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Methyldiazinol at all — not against Nitroglycerin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Methyldiazinol safety at a glance

Methyldiazinol overall Not established There is no reliable safety data for a substance by this name.
Pregnancy Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Nitroglycerin and Methyldiazinol? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Nitroglycerin’s Own FDA Label Lists

This is not an interaction — none of it involves Methyldiazinol. These are the most notable effects listed in the ADVERSE REACTIONS section of Nitroglycerin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. One of them is worth acting on rather than waiting out — marked below.

  • An allergic reaction Worth acting on
  • Flushing
  • Low blood pressure
  • Dizziness
  • A skin rash
  • Headache

From the ADVERSE REACTIONS section of the FDA label for Nitroglycerin. Read the label on DailyMed › Methyldiazinol’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Methyldiazinol side to compare — that is a limit of the record, not a statement that Methyldiazinol has no side effects.

Special populations

Methyldiazinol in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Nitroglycerin

This page covers Methyldiazinol only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Nitroglycerin page lists 26 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Mistletoe (major), Coleus (major), Hawthorn (major) and N-acetyl Cysteine (nac) (major).

By severity: 5 major · 11 moderate · 10 minor.

From our pharmacist’s overview on the Nitroglycerin page

“Nitroglycerin (Nitrostat, Nitro-Bid) exists to open blood vessels quickly during angina, so a supplement that also drops blood pressure, or one that fights the drug's effect, is not a small matter, and this list warrants real care before you add to it. The most serious entries pull in two directions.”

Reviewed by 2 · Jul 18, 2026

Open the Nitroglycerin interaction page

How much people look this up

Where Methyldiazinol and Nitroglycerin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Methyldiazinol
Steady interest

#1,411 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Nitroglycerin
Steady interest

#1,687 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Methyldiazinol reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Methyldiazinol and Nitroglycerin records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Methyldiazinol

What is Methyldiazinol?

There is no reliable scientific or pharmaceutical information about a substance called "Methyldiazinol." It does not appear to be a recognized herb, dietary supplement, or well-documented compound, so we cannot confirm what it is, whether it works, or whether it is safe. Do not take any product marketed under this name without first verifying its identity and contents with a pharmacist or doctor.

An interaction check asks whether these two react with each other — it does not ask whether Methyldiazinol is a good idea for someone in your situation. Here is what our Methyldiazinol record says about it on its own.

Methyldiazinol: dosing

There is no established or safe dose for Methyldiazinol because the substance is not recognized or studied.We cannot recommend any amount. If a product label gives a dose, that does not mean it has been tested for safety.

From our Methyldiazinol monograph — the full record covers uses, side effects and every documented interaction.

Read the full Methyldiazinol monograph & all interactions
Medication

About Nitroglycerin Topical

What Is Nitroglycerin Topical Used For?

Brand names: Nitrostat, Nitrogard SR, Sustachron, Nitro-Bid, Sustachron ER Buccal, Nitroglyn, Nitro Time, Nitrong, Nitrogard, Nitrocine Timecaps, Nitroquick, Rectiv, Gonitro

Rectiv (nitroglycerin ointment 0.4%) is applied rectally to treat moderate to severe pain caused by a chronic anal fissure — a small tear in the lining of the anal canal that causes ongoing discomfort.

See full Nitroglycerin Topical drug information
Keep checking

Other Drugs & Methyldiazinol

Browse every other medication we’ve checked against Methyldiazinol — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Methyldiazinol References

The 1 references that drive our Methyldiazinol monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Methyldiazinol and Nitroglycerin Together: Common Questions

Is it safe to take Methyldiazinol with Nitroglycerin?
We do not list a known interaction between Methyldiazinol and Nitroglycerin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Nitroglycerin interact with any supplements?
Yes. Nitroglycerin has documented interactions with 26 supplements in our database — Methyldiazinol is not one of them. The Nitroglycerin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Nitroglycerin and Methyldiazinol?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.