Drug & supplement interaction

Miracle Fruit + Dupilumab

Dupilumab brand name: Dupixent.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated June 2026 · Pair last verified Sep 13, 2026

The bottom line No known interaction

We found no known interaction between Miracle Fruit and Dupilumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Miracle Fruit and Dupilumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dupilumab and Miracle Fruit in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Miracle Fruit safety at a glance

Miracle Fruit overall Use caution Generally well tolerated as a food, but long-term and high-dose safety has not been well studied.

Pregnancy Use caution There is not enough reliable safety data, so it is best to avoid concentrated supplements and use caution.

Breastfeeding Use caution There is not enough reliable safety data, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dupilumab and Miracle Fruit? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

Keep it in perspective

Miracle Fruit Does Interact With Other Medications

Miracle Fruit has 86 moderate known drug interactions in our database — Dupilumab isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Dupilumab)

Taking anything else?

Check Another of Your Medications Against Miracle Fruit

Covers the 2,830 medications we’ve checked against Miracle Fruit. Pick one to open its full report.

What to actually watch for

What Dupilumab’s Own FDA Label Lists

This is not an interaction — none of it involves Miracle Fruit. These are the most notable effects listed in the ADVERSE REACTIONS section of Dupilumab’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 4 of them are worth acting on rather than waiting out — marked below.

Wheezing Worth acting on
Hives Worth acting on
A higher chance of infection Worth acting on
An allergic reaction Worth acting on
Eye irritation or redness
Dry eyes
Itching mentioned in 12.3% of FDA reports for Dupilumab
A stuffy or runny nose
Blurred vision
Sore throat

Showing the 10 most notable of 19 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Dupilumab. Read the label on DailyMed › Where a percentage is shown, it is the share of 478,975 voluntary FDA FAERS reports for Dupilumab that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Miracle Fruit’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Miracle Fruit side to compare — that is a limit of the record, not a statement that Miracle Fruit has no side effects.

How much people look this up

Where Miracle Fruit and Dupilumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Miracle Fruit

Top half

#621 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Dupilumab

Steady interest

#1,851 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Miracle Fruit reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Miracle Fruit and Dupilumab records this page draws on were last updated June 22, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Miracle Fruit

What is Miracle Fruit?

Making sour foods taste sweet
Sugar substitute or sweetness enhancer
Reducing added sugar intake
Improving taste during chemotherapy
Novelty 'flavor tripping' experiences

Miracle fruit contains a protein called miraculin that temporarily makes sour and acidic foods taste sweet for up to about an hour. It is generally considered safe as a food when used occasionally, but high-quality research on any health benefits is limited. If you are pregnant, breastfeeding, or have a medical condition, check with your pharmacist or doctor first.

Synsepalum dulcificum · Sapotaceae · Fruit (berry) · Fresh berries, freeze-dried tablets, freeze-dried powder, frozen pulp

An interaction check asks whether these two react with each other — it does not ask whether Miracle Fruit is a good idea for someone in your situation. Here is what our Miracle Fruit record says about it on its own.

Miracle Fruit: dosing

There is no official or standardized medical dose for miracle fruit. Products are usually sold as a single fresh berry, a freeze-dried tablet, or a small amount of powder meant for one taste-changing session.The best approach is to follow the directions on the product label and not use more than recommended.

From our Miracle Fruit monograph — the full record covers uses, side effects and every documented interaction.

Read the full Miracle Fruit monograph & all interactions

Medication

About Dupilumab Injection

What Is Dupilumab Injection Used For?

Brand name: Dupixent

Dupixent (dupilumab) injection is approved for several inflammatory conditions. It treats moderate-to-severe atopic dermatitis (eczema) in patients 6 months and older when topical treatments haven't worked well enough. It is also used as an add-on maintenance treatment for moderate-to-severe asthma (ages 6 and up), chronic rhinosinusitis with nasal polyps (ages 12 and up), and COPD with an eosinophilic phenotype in adults.

Additionally, Dupixent treats eosinophilic esophagitis (EoE, a chronic inflammatory condition of the esophagus) in patients 1 year and older weighing at least 15 kg, prurigo nodularis (severe itchy skin nodules) in adults, chronic spontaneous urticaria (hives without a clear trigger) in patients 2 and older who haven't responded to antihistamines, bullous pemphigoid (a blistering skin disease) in adults, and allergic fungal rhinosinusitis in patients 6 and older with a history of sinus surgery. It is not for relief of sudden or acute breathing attacks.

Most-Reported Side Effects for Dupilumab

From FAERS, the FDA’s public side-effect reporting system (478,975 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Pruritus 58,692 reports

Dermatitis atopic 45,026 reports

Rash 38,629 reports

Injection site pain 36,707 reports

Eczema 26,626 reports

See full Dupilumab Injection drug information

Keep checking

Other Drugs & Miracle Fruit

Browse every other medication we’ve checked against Miracle Fruit — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

86Moderate

0Minor

2,743No known interaction

86 Moderate 2,743 No interaction

Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Miracle Fruit page.

No interaction 2,743 drugs checked — show the list

We also checked Miracle Fruit against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Miracle Fruit list.

See the full Miracle Fruit interactions page

See every supplement checked against Dupilumab, ranked by severity

Evidence & sources

Miracle Fruit References

The 1 references that drive our Miracle Fruit monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Obafemi TO, Olaleye MT, Akinmoladun AC. Antidiabetic property of miracle fruit plant (Synsepalum dulcificum Shumach. & Thonn. Daniell) leaf extracts in fructose-fed streptozotocin-injected rats via anti-inflammatory activity and inhibition of carbohydrate

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Miracle Fruit and Dupilumab Together: Common Questions

Is it safe to take Miracle Fruit with Dupilumab?

We do not list a known interaction between Miracle Fruit and Dupilumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Does Miracle Fruit interact with any other medications?

Yes. Miracle Fruit has 86 documented drug interactions in our database — Dupilumab is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Miracle Fruit monograph Uses, safety profile, and every drug interaction in one place Dupilumab Injection drug information The full plain-English guide to this medication Dupilumab supplement interactions Every supplement checked against Dupilumab, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Dupilumab and Miracle Fruit?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.