Mommy's Bliss Gripe Water - OxyContin (Oxycodone) Interaction
Herbal: Mommy's Bliss Gripe Water
Drug: Oxycodone
Brand names:
OxyContin, Roxicodone, OxyIR, Percolone, Oxecta, OxyNeo
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
There were no interactions found between Oxycodone and Mommy's Bliss Gripe Water. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pharmacist Analysis
Mommy's Bliss Gripe Water is intended to help treat colicky infants and soothe gastrointestinal discomfort.
There is no 'standardized' gripe water formula, but generally, gripe water formulas contain a blend of herbal ingredients. Mommy's Bliss contains the following:
- Organic Fennel Seed
- Organic Ginger Root
- Purified Water
- Vegetable Glycerin
- Citrus Bioflavonoid Extract
- Citric Acid
- Sodium Bicarbonate
- Potassium Sorbate
- Natural Fennel Flavor
It is important to note that Mommy's Bliss Gripe Water contains sodium bicarbonate, which is commonly known as baking soda. It is a well-known acid neutralizer and likely plays a key role in relieving colic symptoms if excess acid is at least partially responsible for the symptoms being experienced.
While there is no interaction between Mommy's Bliss Gripe Water and the drug in question here, it is important to note that Mommy's Bliss Gripe Water does have some theoretical ones with other drugs simply based on the fact that two herbals in the product, ginger, and fennel, can affect the metabolism and/or effects of some substances.
We have more details on specific drug-herbal interaction pages.
- Dr. Brian Staiger, PharmDMommy's Bliss Gripe Water Overview
Mommy's Bliss Gripe Water is an over-the-counter product used to soothe colicky babies and infants. It is important to note that 'Gripe water' has been used traditionally since at least the 1800s to help treat colic and gastrointestinal discomfort in infants but 'gripe water' is not a standardized formula. Generally, it is a liquid made from a combination of water and various herbs, such as ginger, fennel, chamomile, licorice, and cinnamon, among others. Some varieties may also contain alcohol or sugar. Mommy's Bliss Gripe water contains fennel seed and ginger. It does not contain sugar or alcohol.
Oxycodone Overview
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Oxycodone is used to relieve moderate to severe pain. Oxycodone extended-release tablets and extended-release capsules are used to relieve severe pain in people who are expected to need pain medication around the clock for a long time and who cannot be treated with other medications. Oxycodone extended-release tablets and extended-release capsules should not be used to treat pain that can be controlled by medication that is taken as needed. Oxycodone extended-release tablets, extended-release capsules, and concentrated solution should only be used to treat people who are tolerant (used to the effects of the medication) to opioid medications because they have taken this type of medication for at least one week. Oxycodone is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain.
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Oxycodone is also available in combination with acetaminophen (Oxycet, Percocet, Roxicet, Xartemis XR, others); aspirin (Percodan); and ibuprofen. This monograph only includes information about the use of oxycodone alone. If you are taking an oxycodone combination product, be sure to read information about all the ingredients in the product you are taking and ask your doctor or pharmacist for more information.
Mommy's Bliss Gripe Water - More Interactions
Mommy's Bliss Gripe Water interacts with 788 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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