Monolaurin + Tofacitinib
Tofacitinib brand names: Xeljanz, Xeljanz XR.
We found no known interaction between Monolaurin and Tofacitinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Monolaurin and Tofacitinib
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Tofacitinib and Monolaurin in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Monolaurin at all — not against Tofacitinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Monolaurin safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Monolaurin in Pregnancy & Breastfeeding
When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of monolaurin when used in medicinal amounts during pregnancy or lactation.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Tofacitinib
This page covers Monolaurin only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tofacitinib page lists 184 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Active Hexose Correlated Compound (ahcc) (moderate).
By severity: 3 major · 143 moderate · 38 minor.
From our pharmacist’s overview on the Tofacitinib page
“Supplements deserve genuine care alongside tofacitinib (Xeljanz, Xeljanz XR), a medicine that deliberately dials down the immune system to control conditions like rheumatoid arthritis and ulcerative colitis. Most of the interactions on this page run through the liver enzymes that clear the drug, meaning an herb can push its blood level…”
Reviewed by 2 · Jul 18, 2026
Taking Monolaurin as Part of a Dietary Supplement Product? Check It for Interactions
We hold 74 real supplement products containing Monolaurin, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Monolaurin. Even though Monolaurin itself has no known interaction with Tofacitinib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Monolaurin and Tofacitinib Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,020 of 1,452 supplements looked up here in the last 7 days
#1,579 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Monolaurin reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Monolaurin and Tofacitinib records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Monolaurin
What is Monolaurin?
- Immune support
- Viral infections (such as herpes or colds)
- Antibacterial support
- Yeast and fungal concerns
- General antimicrobial use
Monolaurin is a compound made from lauric acid, a fatty acid found in coconut oil and breast milk, and it is marketed mostly for immune and antimicrobial support. While laboratory studies suggest it can disrupt certain bacteria, viruses, and fungi, strong human evidence is lacking, so its real-world benefits remain unproven. Talk with your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have a health condition.
Derived from lauric acid (a fatty acid from coconut oil and palm kernel oil) · Capsules, tablets, pellets/beads, powder
An interaction check asks whether these two react with each other — it does not ask whether Monolaurin is a good idea for someone in your situation. Here is what our Monolaurin record says about it on its own.
Monolaurin: dosing
There is no officially established or standardized dose for monolaurin. Studies have used different amounts, and there is no strong human evidence to recommend a specific dose for any condition.Because products vary widely in strength and form, the best approach is to follow the directions on the product label and not exceed the suggested amount. They can help you decide whether it is appropriate for you.
From our Monolaurin monograph — the full record covers uses, side effects and every documented interaction.
About Tofacitinib
What Is Tofacitinib Used For?
Brand names: Xeljanz, Xeljanz XR
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Tofacitinib is used alone or with other medications to treat rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function) in adults who are unable to take or did not respond to one or more tumor necrosis factor (TNF) inhibitor medication(s). It is also used to treat psoriatic arthritis (a condition that causes joint pain and swelling and scales on the skin) in adults who are unable to take or did not respond to or tolerate one or more TNF inhibitor medication(s). Tofacitinib is used to treat ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum) in adults who are unable to take or who did not respond to one or more TNF inhibitor medication(s). It is also used to treat polyarticular juvenile idiopathic arthritis (PJIA; a type of childhood arthritis that affects five or more joints during the first six months of the condition, causing pain, swelling, and loss of function) in children 2 years and older who are unable to take or who did not respond to one or more TNF inhibitor medication(s). Tofacitinib is in a class of medications called Janus kinase (JAK) inhibitors. It works by decreasing the activity of the immune system.
Other Drugs & Monolaurin
Browse every other medication we’ve checked against Monolaurin — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Monolaurin against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Monolaurin list.
Monolaurin References
The 2 references that drive our Monolaurin monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- FDA, Center for Food Safety and Applied Nutrition, Office of Premarket Approval, EAFUS: A food additive database. Website: vm.cfsan.fda.gov/~dms/eafus.html (Accessed 23 February 2006).
- Mancuso AC, Widdice LE, Hughes BL, et al. Five Percent Monolaurin Vaginal Gel for the Treatment of Bacterial Vaginosis: A Randomized Placebo-Controlled Trial. J Low Genit Tract Dis. 2020 Jul;24(3):277-283. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Monolaurin and Tofacitinib Together: Common Questions
Is it safe to take Monolaurin with Tofacitinib?
Does Tofacitinib interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.