Herb & supplement monograph

Feingold Diet Drug Interactions, Uses, Effectiveness, Safety & More

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Interaction report

Drugs that interact with Feingold Diet

0 medications have a known interaction with Feingold Diet, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Feingold Diet. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Feingold Diet combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Feingold Diet: Uses, Safety & Side Effects

The bottom line

The Feingold Diet is an elimination eating plan that removes certain artificial food colors, flavors, sweeteners, preservatives, and some natural salicylate-containing foods, mainly to reduce hyperactivity in children. Scientific evidence is mixed and limited, though a small number of children may be sensitive to specific food additives. If you try it, work with a pediatrician or registered dietitian so your child still gets balanced nutrition.

Common forms
Elimination diet / structured eating plan
People commonly use it for
  • Hyperactivity (ADHD) in children
  • Behavioral problems in kids
  • Attention and focus concerns
  • Childhood sleep and mood issues

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Generally low risk, but restrictive diets in children can lead to nutrition gaps if not supervised.

PregnancyUse caution

The diet is aimed at children; pregnant people should not follow restrictive diets without medical guidance.

BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

The Feingold Diet is not an herb or supplement — it is a structured elimination eating plan. It was developed in the 1970s by Dr. Benjamin Feingold, an allergist, who believed that certain food additives and naturally occurring chemicals could trigger hyperactivity and behavior problems in some children.

The diet removes synthetic food dyes, certain artificial flavorings, three preservatives (BHA, BHT, and TBHQ), and the artificial sweetener aspartame. In its early phase it also limits foods that naturally contain salicylates, such as certain fruits (like apples, grapes, and berries) and other plant foods.

People usually follow it as a trial: remove the targeted foods for a few weeks, watch for changes in behavior, then carefully reintroduce foods to see if symptoms return.

How it works

The main idea is that some children are sensitive to certain food additives and natural chemicals, and that removing these may reduce hyperactive or impulsive behavior.

The diet targets synthetic dyes (such as those labeled FD&C colors), some artificial flavors, certain preservatives, and natural salicylates. The exact biological reason why these might affect behavior is not well understood and remains debated. Proposed mechanisms — such as effects on the nervous system or immune-like reactions — are largely unproven in humans.

Because the plan works by removing foods rather than adding an active compound, any benefit comes from avoiding a trigger, not from a medicine or nutrient.

Effectiveness

Does Feingold Diet work?

Evidence overview · 1 use evaluated
1 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Feingold Diet, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 1 condition — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Attention deficit-hyperactivity disorder (ADHD)
Rating & evidence shown verbatim from Natural Medicines

Some preliminary clinical research suggests that initiating the Feingold diet might reduce subjective evaluations of hyperactivity in children with ADHD; however, poor study quality limits the reliability of these findings. Additionally, other preliminary research shows no symptoms improvement with the Feingold diet.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

The diet itself does not involve taking a drug, so the main concern is nutritional balance. Removing many fruits, vegetables, and processed foods can be hard to maintain and may lead to gaps in vitamins, minerals, or fiber, especially in growing children.

Children with picky eating, food allergies, or existing nutrition problems should be especially careful. Always involve a pediatrician or registered dietitian before starting, and keep the diet as varied and balanced as possible.

For pregnancy and breastfeeding, restrictive elimination diets are generally not advised without medical supervision, because both the parent and baby need consistent, complete nutrition. The diet was designed for children, not for use during pregnancy.

Side effects

The Feingold Diet does not have direct side effects like a medicine. The main risks come from food restriction.

Possible problems include inadequate intake of certain nutrients, difficulty eating outside the home, social stress for the child, and family frustration. Overly strict versions of the diet may unintentionally limit healthy foods, such as many fruits and vegetables.

If a child loses weight, becomes more tired, or shows signs of poor nutrition, stop and talk with a healthcare provider.

Dosing

There is no pill or standardized "dose" for the Feingold Diet — it is a pattern of eating. It is typically done in phases: a stricter starting period that removes targeted additives and salicylate-rich foods, followed by gradual reintroduction to identify specific triggers.

Because the diet can be complex and restrictive, it is best to follow program guidance and work with a registered dietitian or pediatrician to make sure your child's overall diet stays balanced. Check with a pharmacist or doctor before relying on any diet to manage behavior or ADHD symptoms.

Pregnancy & Breastfeeding

Feingold Diet & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 2 references that drive our Feingold Diet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Conners CK, Goyette CH, Southwick DA, et al. Food additives and hyperkinesis: a controlled double-blind experiment. Pediatrics 1976;58:154-66. DOI
  2. Harley JP, Ray RS, Tomasi L, et al. Hyperkinesis and food additives: testing the Feingold hypothesis. Pediatrics 1978;61:818-28. DOI
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Pharmacist Counseling Corner

Feingold Diet: Common Questions

What is Feingold Diet used for, and does it work?
People use Feingold Diet for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Feingold Diet interact with prescription medications?
We do not currently list any known drug interactions for Feingold Diet. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Feingold Diet interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Feingold Diet with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Feingold Diet interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is the Feingold Diet used for?
It is mainly used by parents trying to reduce hyperactivity, inattention, and behavior problems in children, including those with ADHD, by removing certain food dyes, additives, and salicylate-containing foods.
Does the Feingold Diet really work for ADHD?
The evidence is mixed. A minority of children may be genuinely sensitive to certain artificial additives, but the diet is not a proven, stand-alone treatment for ADHD and should not replace standard care.
Is the Feingold Diet safe for kids?
It is generally low risk, but because it removes many foods, it can lead to nutrition gaps. Work with a pediatrician or dietitian to keep your child's diet balanced.
How do I know if my child is sensitive to food additives?
The diet uses a trial-and-reintroduction approach: remove targeted foods, watch for behavior changes, then slowly add foods back to see if symptoms return. A clinician can help you do this safely and accurately.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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