Herb & supplement monograph

Star Of Bethlehem Drug Interactions, Uses, Safety & More

Medically reviewed by ·Updated July 2026
What is this page for?

First and foremost: how Star Of Bethlehem interacts with medications. The heart of this page is the interaction list — every drug Star Of Bethlehem is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Star Of Bethlehem is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Interaction report

Drugs that interact with Star Of Bethlehem

156 medications have a known interaction with Star Of Bethlehem, graded by severity. Select any drug for the full evidence-based detail.

2,830 drugs
Acetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Acetaminophen, Caffeine, Pyrilamine interaction
Acetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Acetaminophen, Pamabrom, Pyrilamine interaction
AcetazolamideAk-Zol, Diamox
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Acetazolamide interaction Acetazolamide drug page: uses, dosage & side effects
Amiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Amiloride, Hydrochlorothiazide interaction Amiloride, Hydrochlorothiazide drug page: uses, dosage & side effects
Ammonium ChlorideAmmonium Chloride
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Ammonium Chloride interaction
Amphotericin, TetracyclineMysteclin-F
Moderate Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with star of Bethlehem might increase the risk of cardiac glycoside toxicity.

Read the full Star Of Bethlehem + Amphotericin, Tetracycline interaction
ArmodafinilNuvigil
Moderate Stimulant Laxatives

Theoretically, excessive use of stimulant laxatives with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Armodafinil interaction Armodafinil drug page: uses, dosage & side effects
Atenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Atenolol, Chlortalidone interaction
Atenolol, ChlorthalidoneTenoretic
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Atenolol, Chlorthalidone interaction
Azelastine Hydrochloride, Fluticasone PropionateDymista
Moderate Corticosteroids

Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.

Read the full Star Of Bethlehem + Azelastine Hydrochloride, Fluticasone Propionate interaction
Azilsartan, ChlorthalidoneEdarbyclor
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Azilsartan, Chlorthalidone interaction
AzithromycinAzasite, Zithromax, Zmax
Moderate Macrolide Antibiotics

Theoretically, taking macrolide antibiotics with star of Bethlehem might increase the risk of cardiac glycoside toxicity.

Read the full Star Of Bethlehem + Azithromycin interaction Azithromycin drug page: uses, dosage & side effects
Beclometasone DipropionateBecotide
Moderate Corticosteroids

Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.

Read the full Star Of Bethlehem + Beclometasone Dipropionate interaction
BeclomethasoneBeclovent, Vanceril
Moderate Corticosteroids

Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.

Read the full Star Of Bethlehem + Beclomethasone interaction Beclomethasone drug page: uses, dosage & side effects
Beclomethasone DipropionateQNASL, Qvar
Moderate Corticosteroids

Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.

Read the full Star Of Bethlehem + Beclomethasone Dipropionate interaction Beclomethasone Dipropionate drug page: uses, dosage & side effects
Benazepril, HydrochlorothiazideLotensin HCT
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Benazepril, Hydrochlorothiazide interaction
BendroflumethiazideAprinox, Naturetin, Neo-NaClex
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Bendroflumethiazide interaction
Bendroflumethiazide, NadololCorzide
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Bendroflumethiazide, Nadolol interaction
Bendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Bendroflumethiazide, Potassium interaction
Bendroflumethiazide, Rauwolfia SerpentinaRauzide
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Bendroflumethiazide, Rauwolfia Serpentina interaction
BenzthiazideExna
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Benzthiazide interaction
BetamethasoneCelestone, Diprolene AF, Diprosone
Moderate Corticosteroids

Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.

Read the full Star Of Bethlehem + Betamethasone interaction Betamethasone drug page: uses, dosage & side effects
Betamethasone DipropionateSernivo
Moderate Corticosteroids

Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.

Read the full Star Of Bethlehem + Betamethasone Dipropionate interaction Betamethasone Dipropionate drug page: uses, dosage & side effects
Betamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
Moderate Corticosteroids

Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.

Read the full Star Of Bethlehem + Betamethasone Dipropionate, Calcipotriene interaction
Betamethasone ValerateLuxiq
Moderate Corticosteroids

Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.

Read the full Star Of Bethlehem + Betamethasone Valerate interaction Betamethasone Valerate drug page: uses, dosage & side effects
BisacodylDulcolax, Gentlax
Moderate Stimulant Laxatives

Theoretically, excessive use of stimulant laxatives with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Bisacodyl interaction Bisacodyl drug page: uses, dosage & side effects
Bisacodyl, DocusateDulcolax Laxative Tabs
Moderate Stimulant Laxatives

Theoretically, excessive use of stimulant laxatives with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Bisacodyl, Docusate interaction
Bismuth Subsalicylate, Metronidazole, TetracyclineHelidac
Moderate Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with star of Bethlehem might increase the risk of cardiac glycoside toxicity.

Read the full Star Of Bethlehem + Bismuth Subsalicylate, Metronidazole, Tetracycline interaction Bismuth Subsalicylate, Metronidazole, Tetracycline drug page: uses, dosage & side effects
Bisoprolol, HydrochlorothiazideZiac
Moderate Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.

Read the full Star Of Bethlehem + Bisoprolol, Hydrochlorothiazide interaction
BudesonideEntocort EC, Eohilia, Pulmicort, Tarpeyo, Uceris
Moderate Corticosteroids

Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.

Read the full Star Of Bethlehem + Budesonide interaction Budesonide drug page: uses, dosage & side effects
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Star Of Bethlehem combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs Star Of Bethlehem affects

Every type of medication (drug category) Star Of Bethlehem is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 7 drug categories Star Of Bethlehem interacts with
CorticosteroidsDigoxin (lanoxin)Diuretic DrugsMacrolide AntibioticsQuinineStimulant LaxativesTetracycline Antibiotics
Corticosteroids

Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.
Star of Bethlehem contains cardiac glycosides. Concomitant use of corticosteroids with star of Bethlehem can increase the therapeutic and adverse effects of long-term corticosteroid use due to potassium depletion and electrolyte imbalance.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking star of Bethlehem in combination with digoxin might have additive effects and increase the risk of toxicity.
Star of Bethlehem contains cardiac glycosides with effects similar to digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.
Star of Bethlehem contains cardiac glycosides. Theoretically, concomitant use of potassium-depleting diuretics and star of Bethlehem can increase the risk of cardiac glycoside toxicity due to potassium depletion.

Likelihood Possible Evidence D
Macrolide Antibiotics

Theoretically, taking macrolide antibiotics with star of Bethlehem might increase the risk of cardiac glycoside toxicity.
Star of Bethlehem contains cardiac glycosides. Macrolide antibiotics appear to increase the gastrointestinal absorption of oral digoxin. Theoretically, concomitant use of macrolide antibiotics might increase the absorption of the cardiac glycosides found in star of Bethlehem and increase the risk of adverse effects.

Likelihood Possible Evidence D
Quinine

Theoretically, taking quinine with star of Bethlehem might increase the risk of cardiac glycoside toxicity.
Star of Bethlehem contains cardiac glycosides. Quinine may reduce the clearance of oral digoxin. Theoretically, concomitant use of quinine might reduce the clearance of cardiac glycosides found in star of Bethlehem and increase the risk of adverse effects.

Likelihood Possible Evidence D
Stimulant Laxatives

Theoretically, excessive use of stimulant laxatives with star of Bethlehem might increase the risk of toxicity.
Star of Bethlehem contains cardiac glycosides. Excessive use of stimulant laxatives can cause diarrhea, resulting in potassium depletion. This might increase the risk of cardiac glycoside toxicity.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with star of Bethlehem might increase the risk of cardiac glycoside toxicity.
Star of Bethlehem contains cardiac glycosides similar to digitalis. Tetracycline antibiotics appear to increase the gastrointestinal absorption of oral digoxin. Theoretically, concomitant use of tetracycline antibiotics might increase the absorption of the cardiac glycosides found in star of Bethlehem and increase the risk of adverse effects.

Likelihood Possible Evidence D
Monograph

Star Of Bethlehem: Uses, Safety & Side Effects

Medically reviewed by · Reviewed July 2026 ·
The bottom line

Star of Bethlehem is a small flowering plant best known as one of the ingredients in Bach flower remedies, where it is used for emotional shock and grief. There is no solid scientific evidence that it treats any medical condition, and the raw plant and bulb are considered toxic, so it should not be eaten. If you choose to use a flower-essence product, treat it as a complement to—not a replacement for—proper medical care.

Scientific name
Ornithogalum umbellatum
Family
Asparagaceae
Part used
Flowers (used in flower remedies); bulb in some traditional preparations
Common forms
Flower essence (Bach flower remedy), liquid drops, often part of blends
People commonly use it for
  • Emotional shock and trauma
  • Grief and bereavement
  • Stress relief
  • Calming and comfort

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

The plant and bulb are toxic if eaten; commercial flower essences are very dilute but lack good safety studies.

PregnancyLikely Unsafe

When used orally. Star of Bethlehem contains toxic cardiac glycosides. Ingestion of star of Bethlehem could result in serious adverse effects.

Read the full pregnancy detail
BreastfeedingLikely Unsafe

When used orally. Star of Bethlehem contains toxic cardiac glycosides. Ingestion of star of Bethlehem could result in serious adverse effects.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Star of Bethlehem (Ornithogalum umbellatum) is a small perennial plant with grass-like leaves and white, star-shaped flowers. It is native to parts of Europe, North Africa, and western Asia, and it now grows wild in many areas, including parts of North America, where it is sometimes considered a weed.

Today the plant is best known as one of the ingredients in Bach flower remedies, a system of highly diluted plant preparations created in the 1930s. In this tradition, Star of Bethlehem is chosen for feelings of shock, fright, or grief. It is one of the five flowers in the popular "Rescue Remedy" blend.

It is important to know that the whole plant, especially the bulb, contains natural toxins and should not be eaten. The flower-essence products are extremely dilute and very different from eating the plant itself.

Uses & effectiveness

People most often use Star of Bethlehem flower essence for emotional concerns such as shock, trauma, grief, and general stress. These uses come from the traditions of flower-essence therapy rather than from solid medical research.

The scientific evidence here is very weak. Studies on Bach flower remedies as a group have generally found that they work no better than placebo (an inactive dummy treatment) for anxiety and stress. There are no good-quality human studies showing that Star of Bethlehem by itself treats any physical or mental health condition.

In short, any benefit people feel may come from the calming ritual of using the product, personal belief, or the natural improvement of mood over time, rather than from a proven drug-like effect.

How it works

Flower essences like Star of Bethlehem are made by placing flowers in water, often in sunlight, and then heavily diluting and preserving the liquid (usually in alcohol). The final product contains little or no measurable amount of the original plant chemicals.

Because the preparation is so dilute, there is no accepted scientific mechanism that explains how it could cause a biological effect in the body. Supporters describe the action in terms of "energy" or emotional balance, but these ideas have not been confirmed by laboratory or clinical science.

The plant itself does contain natural compounds called cardiac glycosides, which can affect the heart and are toxic in larger amounts. These compounds are the reason the raw plant and bulb are dangerous to eat—but they are not present in any meaningful amount in dilute flower essences.

Safety & precautions

The biggest safety concern is the raw plant and bulb, which are poisonous if eaten. Children, pets, and livestock have been harmed by swallowing parts of the plant. Never use homemade preparations or eat any part of Star of Bethlehem.

Commercial flower-essence products are very dilute and are usually preserved in alcohol. The alcohol content may matter for children, people recovering from alcohol use disorder, or anyone avoiding alcohol. There are no high-quality long-term safety studies on these products.

Pregnancy and breastfeeding: Because safety has not been studied, it is best to avoid Star of Bethlehem during pregnancy and while breastfeeding. The alcohol used to preserve many products is another reason for caution.

Always talk with your pharmacist or doctor before using any new supplement, and never use a flower essence in place of medical treatment for serious physical or mental health problems.

Side effects

Because flower essences are so dilute, reported side effects are uncommon and usually mild. Some people may notice irritation from the alcohol used as a preservative, or have an allergic reaction.

Serious effects are linked to eating the actual plant or bulb, not the dilute essence. Poisoning can cause nausea, vomiting, stomach upset, and dangerous changes in heart rhythm because of the natural cardiac glycosides. If someone swallows the plant, seek medical help or contact a poison control center right away.

Star Of Bethlehem: Reported Adverse Effects

Documented safety reports on Star Of Bethlehem from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Star of Bethlehem contains cardiac glycosides, which can cause serious adverse effects.

Serious Adverse Effects (Rare):

Orally: Star of Bethlehem contains toxic cardiac glycosides that can cause cardiac arrhythmia and death.

Reports by condition
Arrhythmia Cardiovascular

Orally, the cardiac glycosides in star of Bethlehem can cause cardiac arrhythmias.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
Cluster headache Neurologic/CNS

Orally, the cardiac glycosides in star of Bethlehem can cause headache and stupor. Visual color disturbances can also occur.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Nausea and vomiting Gastrointestinal

Orally, the cardiac glycosides in star of Bethlehem can cause nausea and vomiting.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no established standard dose for Star of Bethlehem, and no medical dosing has been proven safe or effective. Flower-essence products are typically taken as a few drops by mouth or in water, following the directions on the label.

If you choose to use a product, follow the manufacturer's instructions and do not exceed them. Talk with your pharmacist if you have questions, are pregnant or breastfeeding, are giving it to a child, or are avoiding alcohol. Never make your own preparation from the wild plant.

Pregnancy & Breastfeeding
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 8 references that drive our Star Of Bethlehem monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Burnham TH, ed. Drug Facts and Comparisons, Updated Monthly. Facts and Comparisons, St. Louis, MO.
  5. Waud RA. The action of Ornithogalum umbellatum on the heart. J Pharmacol Exp Ther 1954;111:147-51. DOI
  6. Vogelsang A. Ornithogalum umbellatum in the treatment of congestive heart failure: progress report. J Am Geriatr Soc 1961;9:1096-9.
  7. Vogelsang A. Clinical trial of Ornithogalum umbellatum on the human heart; preliminary report. Can Med Assoc J 1955;73:295-6.
  8. Smith JA, Paterson GR. Rhodexin A and rhodexoside in Ornithogalum umbellatum. J Pharm Pharmacol 1967;19:221-5.
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Star Of Bethlehem

7 brands in our database make a supplement containing Star Of Bethlehem.

Product directory

Supplement products with Star Of Bethlehem

15 products in our database contain Star Of Bethlehem. Open any to see its full ingredient list and every drug interaction we check.

BreatheXX by Viatrexx Bio Incorporated Liquid 1.7 Ounce(s) · 50 mL View ingredients & interactions Distress Remedy by Nature's Sunshine Flower Essence Formula Liquid 1.9 fl. Oz. · 57 mL View ingredients & interactions Five-Flower Formula by Flower Essence Services Liquid 1 fl. Oz. · 30 mL View ingredients & interactions Five-Flower Formula by Flower Essence Services Liquid 1 fl. Oz. · 30 mL View ingredients & interactions Five-Flower Formula Flower Essence by Flower Essence Services Liquid 0.25 fl. Oz. · 7.5 mL View ingredients & interactions Five-Flower Formula Flower Essence Spray by Flower Essence Services Liquid 1 Fluid Ounce(s) · 30 Milliliter(s) View ingredients & interactions Grace by Flower Essence Services Liquid 1 fl. Oz. · 30 mL View ingredients & interactions Multi-Flower by Energique Liquid 1 Fluid Ounce(s) · 30 mL View ingredients & interactions Post-Trauma Stabilizer by Flower Essence Services Liquid 1 fl. Oz. · 30 mL View ingredients & interactions Star of Bethlehem Flower Essence by Flower Essence Services Liquid 1 fl. Oz. · 30 mL View ingredients & interactions Star of Bethlehem Flower Essence by Flower Essence Services Liquid 0.25 fl. Oz. · 7.5 mL View ingredients & interactions Stomach Ache by BIOVEA Homeopathics Liquid 1 fl. Oz. · 30 mL View ingredients & interactions Zeolite Enhanced With DHQ by Get Healthy Again Liquid 2 Oz(s) · 60 mL View ingredients & interactions Distress Remedy by Nature's Sunshine Liquid 2 fl. Oz. · 60 mL Off market View ingredients & interactions Distress Remedy by Nature's Sunshine Liquid 2 fl. Oz. · 60 mL Off market View ingredients & interactions
Pharmacist Counseling Corner

Star Of Bethlehem: Common Questions

Does Star Of Bethlehem interact with prescription medications?
Yes. We list 156 medications with a known interaction with Star Of Bethlehem. Use the checker above to see how Star Of Bethlehem interacts with a specific drug.
How are Star Of Bethlehem interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Star Of Bethlehem with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Star Of Bethlehem interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Star Of Bethlehem used for?
It is mainly used as a flower essence for emotional shock, grief, and stress. These uses are traditional, and there is no strong scientific proof that it treats any condition.
Is Star Of Bethlehem safe to take?
The dilute flower essence is generally low-risk for most adults, but it has not been well studied. The raw plant and bulb, however, are toxic and should never be eaten.
Can I use it during pregnancy or while breastfeeding?
It is best to avoid it, since there is no reliable safety information and many products contain alcohol. Check with your doctor or pharmacist first.
Is Star Of Bethlehem the same as Rescue Remedy?
No. Star Of Bethlehem is one of several flower essences blended together to make Rescue Remedy, a popular Bach flower product used for stress.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Keep exploring

Products that contain Star Of Bethlehem

A rotating sample of real supplements in our database that list Star Of Bethlehem — open any to see its full ingredients and every drug interaction we check.

See all 15 products with Star Of Bethlehem →
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