Interactions on record — worth a quick check against your medications. Based on 2 of 9 ingredients. Check your meds →
Dietary supplement

Grace Ingredients & Drug Interactions

by Flower Essence Services

Grace label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Grace against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Grace is a dietary supplement by Flower Essence Services with 9 active ingredients. Its ingredients are commonly taken for emotional shock and trauma, grief and bereavement, stress relief.Based on those ingredients, 156 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ornithogalum umbellatum. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Grace by Flower Essence Services

Ask about any prescription or over-the-counter medication and we check it for interactions with Grace by Flower Essence Services — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Grace by Flower Essence Services

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 9 active ingredients.
  • “infusions of flowers of” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Grace contains 9 ingredients, most of them flower essences from lily family plants. The active ingredient we have data for is star of Bethlehem (Ornithogalum umbellatum), which contains cardiac glycosides—naturally occurring compounds that affect heart function.

The product also includes American Adder's Tongue (Erythronium purpurascens) and several Calochortus and Lilium species, along with essential oil of damask rose. The inactive ingredients are water and brandy, which serve as the liquid base.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for any ingredient in Grace. The evidence for whether this product works for its intended purpose isn't established in the information available to us.

The evidence, ingredient by ingredient Star Of Bethlehem American Adder's Tongue

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Star of Bethlehem carries real safety concerns. It's toxic if eaten whole, and while commercial flower essences are very dilute, they lack good safety studies.

The cardiac glycosides it contains can cause serious heart rhythm problems (arrhythmias), headaches, visual color disturbances, and in rare cases, death. American Adder's Tongue has very limited human safety data; when the plant is eaten, it can cause stomach upset or vomiting.

During pregnancy, star of Bethlehem is rated unsafe, and there isn't enough safety information on American Adder's Tongue to know either way—talk with your doctor or pharmacist for personalized advice. Breastfeeding is not recommended with either ingredient, as safety data are either absent or advise against it.

Side effects, ingredient by ingredient Star Of Bethlehem American Adder's Tongue

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Star Of Bethlehem.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 156 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Grace, double-check with your doctor or pharmacist if you take digoxin (Lanoxin) or any heart medication with cardiac effects. Also confirm your use if you're on water pills (diuretics), long-term corticosteroids, macrolide or tetracycline antibiotics, stimulant laxatives, or quinine.

Altogether, these interactions span 156 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Grace is built around star of Bethlehem, an ingredient with serious heart-related risks and multiple documented medication interactions—particularly with heart and water-pill medications. If you take any prescription drugs, especially for your heart or blood pressure, you need to check with your own doctor or pharmacist before using this product.

It's not recommended during pregnancy or while breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Grace, straight from the product label.

Brand Flower Essence Services
Barcode (UPC) 782932151110
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Jan 24, 2014
DSLD ID 29862
Product type Botanical
Supplement form Liquid
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Grace by Flower Essence Services, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Spray(s)
Maximum serving Sizes:
4 Spray(s)
UPC/BARCODE
782932151110
IngredientAmount% DV
infusions of flowers of0 NP--
Ornithogalum umbellatum0 NP--
Lilium longiflorum0 NP--
Calochortus lechtlinii0 NP--
Calochortus splendens0 NP--
Calochortus tolmiei0 NP--
Lilium washingtonianum0 NP--
Erythronium purpurascens0 NP--
Hesperocallis undulata0 NP--
essential oil of damask rose0 NP--

Other ingredients: Water, Brandy

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Certified organic by Stellar Certification Services, Inc.

Brand IP Statement(s)

Certified Biodynamic(R) by the Demeter Association, Inc.

Seals/Symbols

DEMETER(R)

FES Quintessentials(TM)

General Statements

BEST BY 04/2022

A symphony of white lilies to nourish feminine qualities of Soul

flower essence & essential oil

Suggested/Recommended/Usage/Directions

Suggested use: Spray four times daily in mouth or around body. Shake well before use.

FDA Statement of Identity

herbal supplement

General

120412

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Grace by Flower Essence Services label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Grace label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Grace by Flower Essence Services

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Spray(s) Dosage formLiquid Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Infusions of flowers of

0 NP per serving

Essential oil of damask rose

0 NP per serving

Other (inactive) ingredients: Water, Brandy. These complete the product’s ingredient list but are not active constituents.

Interaction report

Grace by Flower Essence Services Drug Interactions

Want to check YOUR meds against Grace?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
156Drugs
156 Moderate

Ingredients driving the most interactions

Ornithogalum umbellatum 156

Individual Drug Interactions

The ingredients in Grace interact with 156 drugs. Click any drug to see the details.

1 of the 9 ingredients in Grace interact with drugs. Each result below shows which ingredient is responsible. Ornithogalum umbellatum

Each ingredient & the kinds of drugs it affects

For each ingredient in Grace with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Ornithogalum umbellatum7 drug types · 156 drugs

Corticosteroids

Theoretically, taking star of Bethlehem with prolonged corticosteroid therapy might increase the risk of toxicity.
Star of Bethlehem contains cardiac glycosides. Concomitant use of corticosteroids with star of Bethlehem can increase the therapeutic and adverse effects of long-term corticosteroid use due to potassium depletion and electrolyte imbalance.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking star of Bethlehem in combination with digoxin might have additive effects and increase the risk of toxicity.
Star of Bethlehem contains cardiac glycosides with effects similar to digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, taking diuretics with star of Bethlehem might increase the risk of toxicity.
Star of Bethlehem contains cardiac glycosides. Theoretically, concomitant use of potassium-depleting diuretics and star of Bethlehem can increase the risk of cardiac glycoside toxicity due to potassium depletion.

Likelihood Possible Evidence D
Macrolide Antibiotics

Theoretically, taking macrolide antibiotics with star of Bethlehem might increase the risk of cardiac glycoside toxicity.
Star of Bethlehem contains cardiac glycosides. Macrolide antibiotics appear to increase the gastrointestinal absorption of oral digoxin. Theoretically, concomitant use of macrolide antibiotics might increase the absorption of the cardiac glycosides found in star of Bethlehem and increase the risk of adverse effects.

Likelihood Possible Evidence D
Quinine

Theoretically, taking quinine with star of Bethlehem might increase the risk of cardiac glycoside toxicity.
Star of Bethlehem contains cardiac glycosides. Quinine may reduce the clearance of oral digoxin. Theoretically, concomitant use of quinine might reduce the clearance of cardiac glycosides found in star of Bethlehem and increase the risk of adverse effects.

Likelihood Possible Evidence D
Stimulant Laxatives

Theoretically, excessive use of stimulant laxatives with star of Bethlehem might increase the risk of toxicity.
Star of Bethlehem contains cardiac glycosides. Excessive use of stimulant laxatives can cause diarrhea, resulting in potassium depletion. This might increase the risk of cardiac glycoside toxicity.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with star of Bethlehem might increase the risk of cardiac glycoside toxicity.
Star of Bethlehem contains cardiac glycosides similar to digitalis. Tetracycline antibiotics appear to increase the gastrointestinal absorption of oral digoxin. Theoretically, concomitant use of tetracycline antibiotics might increase the absorption of the cardiac glycosides found in star of Bethlehem and increase the risk of adverse effects.

Likelihood Possible Evidence D
Ornithogalum umbellatum full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Grace, from the product label.

Flower Essence Services

See all Flower Essence Services products
Phone Number
800-548-0075
Pharmacist Counseling Corner

Grace by Flower Essence Services: Common Questions

Does Grace by Flower Essence Services interact with any medications?
Yes. Based on its ingredients, Grace has a known interaction with 156 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Grace contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is star of Bethlehem safe to take by mouth?
No. Star of Bethlehem is toxic if eaten whole, and while commercial flower essences are very dilute, they lack good safety studies. The cardiac glycosides it contains can cause serious heart rhythm problems and, in rare cases, death. This is a significant safety concern.
Can I take this while I'm pregnant or breastfeeding?
No—star of Bethlehem is rated unsafe during pregnancy. There isn't enough safety information on the other ingredients to know either way, so talk with your doctor or pharmacist for personalized advice. Breastfeeding is also not recommended with the ingredients in this product.
What are cardiac glycosides, and why do they matter?
Cardiac glycosides are compounds that affect how your heart beats. Star of Bethlehem contains them, and they can cause dangerous heart rhythm problems (arrhythmias), headaches, and visual disturbances. They're also the reason this product interacts with so many heart and kidney medications.
Does this product have any proven effectiveness?
We don't have effectiveness data for Grace or its ingredients. The evidence for whether it works for its intended purpose isn't established in the information available to us.
What are the inactive ingredients?
Grace contains water and brandy as its inactive ingredients—the liquid base for the flower essences. There are no other fillers or binders listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Grace label
Go deeper

The Full Monographs Behind Grace’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Star Of Bethlehem

Interacts with 156 drugs

Star of Bethlehem is a small flowering plant best known as one of the ingredients in Bach flower remedies, where it is used for emotional shock and grief. There is no solid scientific eviden...

Read the full Star Of Bethlehem monograph → Herb & supplement monograph

American Adder's Tongue

American Adder's Tongue (Erythronium americanum) is a woodland lily used in traditional folk medicine, mainly as a crushed-leaf poultice for skin ulcers and wounds. There is very little mode...

Read the full American Adder's Tongue monograph →
Sources

Sources & How We Checked

Grace's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Star Of Bethlehem 8 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Burnham TH, ed. Drug Facts and Comparisons, Updated Monthly. Facts and Comparisons, St. Louis, MO.
  5. Waud RA. The action of Ornithogalum umbellatum on the heart. J Pharmacol Exp Ther 1954;111:147-51. DOI
  6. Vogelsang A. Ornithogalum umbellatum in the treatment of congestive heart failure: progress report. J Am Geriatr Soc 1961;9:1096-9.
  7. Vogelsang A. Clinical trial of Ornithogalum umbellatum on the human heart; preliminary report. Can Med Assoc J 1955;73:295-6.
  8. Smith JA, Paterson GR. Rhodexin A and rhodexoside in Ornithogalum umbellatum. J Pharm Pharmacol 1967;19:221-5.

See these in context on the Star Of Bethlehem monograph →

American Adder's Tongue 2 references
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source

See these in context on the American Adder's Tongue monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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