Herb & supplement monograph

Pheasant's Eye Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS ·Updated July 2026

What is this page for?

First and foremost: how Pheasant's Eye interacts with medications. The heart of this page is the interaction list — every drug Pheasant's Eye is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Pheasant's Eye is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Reviewed by licensed pharmacists Sourced from Natural Medicines

On this page

Pheasant's Eye Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the risk of a clinically significant Pheasant's Eye drug interaction is real and moderate for most people, and combining it with digoxin is considered unsafe. Nearly all listed interactions are rated moderate, and the single major one involves digoxin, where use together is contraindicated.

Interactions deserving the most attention

The clearest concern is digoxin. Pheasant's Eye naturally contains cardiac glycosides, the same type of compound as digoxin, so taking them together could push levels into the toxic range and affect heart rhythm. Also worth noting are potassium-depleting diuretics and long-term corticosteroids, because losing potassium can make these plant glycosides more toxic to the heart; stimulant laxatives raise a similar concern. These heart-related effects are why this supplement deserves extra care.

What the rest of the list means

The long list of moderate interactions mostly reflects one shared theme rather than many separate proven problems: medicines that lower potassium, or that could increase absorption or slow clearance of the plant's glycosides, might in theory add to its effects on the heart. Most of these concerns come from theory and indirect evidence, not from studies showing harm in people taking the combinations.

Check your medications against Pheasant's Eye

Based on HelloPharmacist’s Pheasant's Eye interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Pheasant's Eye

156 medications have a known interaction with Pheasant's Eye, graded by severity. Select any drug for the full evidence-based detail.

1 major interaction. These combinations can be clinically significant — best avoided, or used only with close professional supervision. Always check with your pharmacist before combining them with Pheasant's Eye.

Don’t want to scroll the list? Just ask.

Tell us the medications you take and we’ll check each one against Pheasant's Eye using our pharmacist-reviewed interaction data.

AI summaries are generated from our Pheasant's Eye interaction data for education only — always confirm with your pharmacist. How we use AI

2,830 drugs

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
Each drug listed above links to the full report for that exact Pheasant's Eye combination — clinical detail, likelihood, evidence level, and citations.
Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

The big picture

The kinds of drugs Pheasant's Eye affects

Every type of medication (drug category) Pheasant's Eye is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 7 drug categories Pheasant's Eye interacts with

Digoxin (lanoxin)CorticosteroidsDiuretic DrugsMacrolide AntibioticsQuinineStimulant LaxativesTetracycline Antibiotics

Digoxin (Lanoxin)

Theoretically, taking pheasant's eye with digoxin might increase the risk of cardiac glycoside toxicity.
Pheasant's eye contains cardiac glycosides. Concomitant use of digoxin with pheasant's eye is contraindicated due to an increased risk of cardiac glycoside toxicity.

Likelihood Probable Evidence D

Corticosteroids

Theoretically, using pheasant's eye with prolonged corticosteroid therapy can cause cardiac glycoside toxicity.
Pheasant's eye contains cardiac glycosides. Concomitant use of corticosteroids with pheasant's eye can increase the therapeutic and adverse effects of long-term corticosteroid use due to potassium depletion and electrolyte imbalance.