Herb & supplement monograph

Hedge Mustard Drug Interactions, Uses, Safety & More

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS ·Updated July 2026

What is this page for?

First and foremost: how Hedge Mustard interacts with medications. The heart of this page is the interaction list — every drug Hedge Mustard is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Hedge Mustard is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Reviewed by licensed pharmacists Sourced from Natural Medicines

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Hedge Mustard Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the overall risk of a clinically significant Hedge Mustard drug interaction appears low for most people, though those taking heart medicines deserve extra care. None of the listed interactions are rated major, and every one rests on theoretical reasoning rather than documented reactions in people.

Interactions deserving the most attention

The concern that stands out most involves digoxin. Hedge mustard's flowering parts contain compounds that act on the heart the same way digoxin does, so combining them could theoretically add up to too much effect. The same worry extends to medicines that lower potassium, such as potassium-depleting diuretics and overused stimulant laxatives, because low potassium makes these heart-active compounds more toxic. Certain antibiotics and quinine could also, in theory, raise levels of these compounds in the body.

What the rest of the list means

Although the list of interacting medications is long, nearly all of it traces back to this single theoretical concern about hedge mustard's heart-active compounds. None of these effects has been confirmed in human studies, so a medication appearing on the list does not mean the combination has actually caused harm.

Check your medications against Hedge Mustard

Based on HelloPharmacist’s Hedge Mustard interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Hedge Mustard

133 medications have a known interaction with Hedge Mustard, graded by severity. Select any drug for the full evidence-based detail.

Don’t want to scroll the list? Just ask.

Tell us the medications you take and we’ll check each one against Hedge Mustard using our pharmacist-reviewed interaction data.

AI summaries are generated from our Hedge Mustard interaction data for education only — always confirm with your pharmacist. How we use AI

2,830 drugs

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
Each drug listed above links to the full report for that exact Hedge Mustard combination — clinical detail, likelihood, evidence level, and citations.
Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

The big picture

The kinds of drugs Hedge Mustard affects

Every type of medication (drug category) Hedge Mustard is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 6 drug categories Hedge Mustard interacts with

Digoxin (lanoxin)Diuretic DrugsMacrolide AntibioticsQuinineStimulant LaxativesTetracycline Antibiotics

Digoxin (Lanoxin)

Theoretically, taking hedge mustard with digoxin might increase the risk of cardiac glycoside toxicity.

The flowering above ground parts of hedge mustard contain cardioactive glycosides. Theoretically, taking hedge mustard with digoxin might increase the risk of cardiac glycoside toxicity.