Drug & supplement interaction

Pheasant's Eye + Clopidogrel

Clopidogrel brand name: Plavix.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Pheasant's Eye and Clopidogrel in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Pheasant's Eye and Clopidogrel

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Clopidogrel and Pheasant's Eye in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Pheasant's Eye safety at a glance

Pheasant's Eye overall Avoid The plant is poisonous and contains potent heart-affecting compounds with a very narrow safety margin.
Pregnancy Likely Unsafe When used orally for self-medication. Read the full pregnancy detail
Breastfeeding Likely Unsafe When used orally for self-medication. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Clopidogrel and Pheasant's Eye? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Clopidogrel

Interactions in our licensed database are recorded against drug classes, not just single drug names. Clopidogrel is filed under 7 classifications — including cytochrome p450 2c9 (cyp2c9) substrates, anticoagulant/antiplatelet drugs, cytochrome p450 1a2 (cyp1a2) substrates. Pheasant's Eye has documented interactions with 7 drug classes — the most serious being digoxin (lanoxin) (major), corticosteroids (moderate) and diuretic drugs (moderate) — and none of Clopidogrel’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Pheasant's Eye Does Interact With Other Medications

Pheasant's Eye has 1 major, 155 moderate known drug interactions in our database — Clopidogrel isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Pheasant's Eye

Covers the 2,830 medications we’ve checked against Pheasant's Eye. Pick one to open its full report.

What to actually watch for

What Pheasant's Eye Itself Has Been Linked To

This is not an interaction — nothing below involves Clopidogrel. It is the side-effect record for Pheasant's Eye on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Pheasant's Eye, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • An irregular heartbeat Worth acting on Additional detail

    “Orally, pheasant's eye might be unsafe due to its cardiac glycoside constituents.

    Serious Adverse Effects (Rare):

    Orally: Theoretically, digitalis-like effects including cardiac arrhythmia, diarrhea, nausea, and vomiting.”

    Pheasant's Eye · Natural Medicines adverse-effect record, reported in arrhythmia.

  • Diarrhea / Vomiting / Nausea Additional detail

    “Orally, adverse effects may include diarrhea, nausea, and vomiting (2). Pheasant's eye contains cardiac glycosides and can cause serious adverse effects when used orally without appropriate medical supervision (18,512,104545).”

    Pheasant's Eye · Natural Medicines adverse-effect record, reported in diarrhea.

    4 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    3. 512. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
    4. 104545. Shang X, Miao X, Yang F, et al. The genus Adonis as an important cardiac folk medicine: A review of the ethnobotany, phytochemistry and pharmacology. Front Pharmacol. 2019;10:25. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Pheasant's Eye — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Clopidogrel’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Clopidogrel column appears here.

Special populations

Pheasant's Eye in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

When used orally for self-medication.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Pheasant's Eye or Clopidogrel

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Pheasant's Eye or Clopidogrel, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Clopidogrel

This page covers Pheasant's Eye only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Clopidogrel page lists 309 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Danshen (major), Grapefruit (major), Piracetam (major) and St. John's Wort (major).

By severity: 5 major · 258 moderate · 46 minor.

From our pharmacist’s overview on the Clopidogrel page

“Clopidogrel (Plavix) keeps platelets from sticking together after a stent, heart attack, or stroke, which makes this a list to take carefully. Of the 309 supplements and herbs on file, 202 carry blood-thinning or antiplatelet activity of their own and can stack bleeding risk on top of the drug's, while most of the rest change how the l…”

Reviewed by 2 · Jul 18, 2026

Open the Clopidogrel interaction page

How much people look this up

Where Pheasant's Eye and Clopidogrel Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Pheasant's Eye
Steady interest

#1,098 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Clopidogrel
Top 1%

#14 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pheasant's Eye reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Pheasant's Eye and Clopidogrel records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Pheasant's Eye

What is Pheasant's Eye?

  • Heart failure symptoms
  • Irregular or weak heartbeat
  • Fluid retention (as a diuretic)
  • Nervous heart complaints
  • Mild anxiety with heart palpitations

Pheasant's Eye (Adonis vernalis) is a toxic plant that contains heart-acting compounds similar to those in foxglove. It has been used in traditional and old European medicine for heart problems, but it is poisonous and has a very narrow margin of safety. You should not use it on your own — it should only ever be considered under direct medical supervision, if at all.

Adonis vernalis · Ranunculaceae · Dried above-ground parts (herb), including flowers, stems, and leaves · Tincture, dried herb extract, and standardized preparations (historically); rarely available as a non-prescription supplement

An interaction check asks whether these two react with each other — it does not ask whether Pheasant's Eye is a good idea for someone in your situation. Here is what our Pheasant's Eye record says about it on its own.

Pheasant's Eye: dosing

There is no safe, established over-the-counter dose for Pheasant's Eye, and we will not suggest one. Because the plant is toxic and the gap between an active dose and a poisonous dose is very small, dosing was historically left to trained practitioners using standardized, carefully measured preparations.We do not recommend using this plant on your own. If a product containing it is ever offered to you, do not take it without first speaking to a doctor or pharmacist. Always follow professional medical guidance rather than a product label alone.

From our Pheasant's Eye monograph — the full record covers uses, side effects and every documented interaction.

Read the full Pheasant's Eye monograph & all interactions
Medication

About Clopidogrel

What Is Clopidogrel Used For?

Brand name: Plavix

Clopidogrel tablets are used to reduce the risk of heart attack and stroke in people with acute coronary syndrome (ACS) — including unstable angina and non-ST-elevation or ST-elevation heart attacks — and in people with a history of recent heart attack, recent stroke, or established peripheral arterial disease. For ACS, it is typically given alongside aspirin.

It works by preventing platelets (blood cells that trigger clotting) from clumping together, which helps keep arteries open and lowers the chance of a dangerous clot forming.

Most-Reported Side Effects for Clopidogrel

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 10,950 reports
Myocardial infarction 10,227 reports
Fatigue 9,428 reports
Gastrointestinal haemorrhage 8,776 reports
Nausea 8,686 reports
See full Clopidogrel drug information
Keep checking

Other Drugs & Pheasant's Eye

Browse every other medication we’ve checked against Pheasant's Eye — both the ones with a known interaction and the ones without. Select any drug for the full detail.

1Major
155Moderate
0Minor
2,673No known interaction
Major

1 interaction

Moderate

155 interactions

Showing 60 of 155 moderate interactions — see all 155 on the Pheasant's Eye page.

No interaction 2,673 drugs checked — show the list
Evidence & sources

Pheasant's Eye References

The 7 references that drive our Pheasant's Eye monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  4. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  5. Burnham TH, ed. Drug Facts and Comparisons, Updated Monthly. Facts and Comparisons, St. Louis, MO.
  6. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  7. Shang X, Miao X, Yang F, et al. The genus Adonis as an important cardiac folk medicine: A review of the ethnobotany, phytochemistry and pharmacology. Front Pharmacol. 2019;10:25. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Pheasant's Eye and Clopidogrel Together: Common Questions

Is it safe to take Pheasant's Eye with Clopidogrel?
We do not list a known interaction between Pheasant's Eye and Clopidogrel. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Pheasant's Eye and Clopidogrel combination checked?
Interactions in our licensed database are recorded against drug classes. Clopidogrel is filed under 7 classifications, and Pheasant's Eye has documented interactions with 7 drug classes — none of Clopidogrel's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Pheasant's Eye interact with any other medications?
Yes. Pheasant's Eye has 156 documented drug interactions in our database — Clopidogrel is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Clopidogrel interact with any supplements?
Yes. Clopidogrel has documented interactions with 309 supplements in our database — Pheasant's Eye is not one of them. The Clopidogrel interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Clopidogrel and Pheasant's Eye?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.