Drug & supplement interaction

Mountain Ash + Foscarnet

Foscarnet brand name: Foscavir.

Moderate Interaction
The bottom line Moderate

Mountain Ash has a moderate interaction with Foscarnet. Taking large amounts of fresh mountain ash berries may cause kidney damage due to its parasorbic acid constituent.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
Know someone taking this? Share
Interaction report

Mountain Ash and Foscarnet

Here is the interaction we found between these two, with the evidence behind it.

Moderate

NEPHROTOXIC DRUGS

Why this applies to Foscarnet

Foscarnet falls under NEPHROTOXIC DRUGS — the group Mountain Ash interacts with.

Taking large amounts of fresh mountain ash berries may cause kidney damage due to its parasorbic acid constituent. Theoretically, taking mountain ash berries with nephrotoxic drugs might increase the risk for kidney damage. Until more is known, advise patients to avoid taking mountain ash berries if they are taking other potentially nephrotoxic drugs.
Some potentially nephrotoxic drugs include cyclosporine (Neoral, Sandimmune); aminoglycosides including amikacin (Amikin), gentamicin (Garamycin, Gentak, others), and tobramycin (Nebcin, others); nonsteroidal anti-inflammatory drugs (NSAIDs) including ibuprofen (Advil, Motrin, Nuprin, others), indomethacin (Indocin), naproxen (Aleve, Anaprox, Naprelan, Naprosyn), piroxicam (Feldene); and numerous others.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the thing to know about foscarnet: it's already one of the harder antivirals on the kidneys. Kidney injury is one of its most common and serious side effects, which is why your team watches your bloodwork and keeps you well hydrated while you're on it. So anything else that could stress the kidneys deserves a second look.

Fresh mountain ash berries contain a compound called parasorbic acid that, in large amounts, may be tough on the kidneys. Stacking that on top of foscarnet could, in theory, add to that risk. I'll be honest: this concern is theoretical, based on how the berry behaves rather than real human studies, and cooked culinary amounts (jams, syrups) are far less concerning than concentrated berry supplements. Still, while you're on foscarnet, the safest move is to skip mountain ash supplements and check with your doctor or pharmacist first.

References
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Mountain Ash Also Interacts With Other Medications

Mountain Ash has 354 moderate known drug interactions in our database — the Foscarnet one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Mountain Ash

Covers the 2,830 medications we’ve checked against Mountain Ash. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Foscarnet

This page covers Mountain Ash only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Foscarnet page lists 12 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Asarabacca (major), Siberian Cocklebur (major), Aristolochia (moderate), Biofeedback (moderate) and Dendrobium (moderate).

By severity: 2 major · 9 moderate · 1 minor.

Open the Foscarnet interaction page

One more smart check

Taking Mountain Ash as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Mountain Ash, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Mountain Ash. Your product may carry other ingredients that interact with Foscarnet too, on top of Mountain Ash — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Mountain Ash and Foscarnet Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Mountain Ash
Top half

#667 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Foscarnet
Top half

#1,201 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Mountain Ash

What is Mountain Ash?

Mountain Ash
  • Sore throat and hoarseness
  • Digestive upset and constipation
  • Cough and chest congestion
  • Mild urinary complaints
  • Source of vitamin C in folk medicine

Mountain ash (rowan) is a northern-hemisphere tree whose bright red berries are traditionally cooked into jams, syrups, and teas. There is very little reliable human research to support any medical use, and raw berries contain compounds that can cause stomach upset, so cooking is important. If you want to try it, talk with your pharmacist or doctor first.

Read the full Mountain Ash monograph & all interactions
Medication

About Foscarnet Injection

What Is Foscarnet Injection Used For?

Brand name: Foscavir

Foscavir (foscarnet sodium injection) is approved to treat CMV retinitis — a viral eye infection — in patients with AIDS. It can also be used in combination with ganciclovir for CMV retinitis that has come back after treatment with either drug alone.

Foscavir is also approved to treat acyclovir-resistant mucocutaneous HSV infections — herpes sores on the skin or mucous membranes that no longer respond to acyclovir — in immunocompromised patients. It is approved only for immunocompromised individuals and has not been proven safe or effective for other CMV or HSV infections, or for people with healthy immune systems.

See full Foscarnet Injection drug information
Keep checking

Other Drugs & Mountain Ash

Browse every other medication we’ve checked against Mountain Ash — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
354Moderate
0Minor
2,475No known interaction
Moderate

354 interactions

Showing 60 of 354 moderate interactions — see all 354 on the Mountain Ash page.

No interaction 2,475 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Pharmacist Counseling Corner

Taking Mountain Ash and Foscarnet Together: Common Questions

Can you take Mountain Ash with Foscarnet?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Mountain Ash and Foscarnet interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Foscarnet and Mountain Ash?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.