Drug & supplement interaction

Mouse-ear Hawkweed + Idelalisib

Idelalisib brand name: Zydelig.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Mouse-ear Hawkweed and Idelalisib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Mouse-ear Hawkweed and Idelalisib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Idelalisib and Mouse-ear Hawkweed in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Mouse-ear Hawkweed at all — not against Idelalisib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Mouse-ear Hawkweed safety at a glance

Mouse-ear Hawkweed overall Use caution Traditionally used but lacking modern human safety and effectiveness data, so use cautiously.
Pregnancy Avoid Not enough safety information; best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Idelalisib and Mouse-ear Hawkweed? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Idelalisib’s Own FDA Label Lists

This is not an interaction — none of it involves Mouse-ear Hawkweed. These are the most notable effects listed in the ADVERSE REACTIONS section of Idelalisib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 8 of them are worth acting on rather than waiting out — marked below.

  • Dehydration Worth acting on mentioned in 3.5% of FDA reports for Idelalisib
  • A severe skin reaction Worth acting on
  • A low platelet count Worth acting on
  • Anemia Worth acting on
  • A low white blood cell count Worth acting on
  • A higher chance of infection Worth acting on mentioned in 6.2% of FDA reports for Idelalisib
  • Liver problems Worth acting on
  • An allergic reaction Worth acting on
  • Heartburn
  • Chills

Showing the 10 most notable of 22 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Idelalisib. Read the label on DailyMed › Where a percentage is shown, it is the share of 7,040 voluntary FDA FAERS reports for Idelalisib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Mouse-ear Hawkweed’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Mouse-ear Hawkweed side to compare — that is a limit of the record, not a statement that Mouse-ear Hawkweed has no side effects.

Everything else you take

See Every Supplement That Interacts With Idelalisib

This page covers Mouse-ear Hawkweed only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Idelalisib page lists 143 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 100 moderate · 40 minor.

From our pharmacist’s overview on the Idelalisib page

“Idelalisib (Zydelig) treats certain blood cancers, work that leaves little room for error, so start with the three major-rated entries on this page. Grapefruit raises idelalisib levels and the risk of side effects with them, St.”

Reviewed by 2 · Jul 18, 2026

Open the Idelalisib interaction page

How much people look this up

Where Mouse-ear Hawkweed and Idelalisib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Mouse-ear Hawkweed
Steady interest

#1,278 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Idelalisib
Steady interest

#2,226 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Mouse-ear Hawkweed is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Mouse-ear Hawkweed reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Mouse-ear Hawkweed and Idelalisib records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Mouse-ear Hawkweed

What is Mouse-ear Hawkweed?

Mouse-ear Hawkweed
  • Urinary tract and kidney support
  • Mild diuretic (increasing urine flow)
  • Digestive complaints
  • Coughs and respiratory irritation
  • Wound and skin care (astringent)

Mouse-ear hawkweed is a traditional European herb used mainly for urinary, digestive, and respiratory complaints, but modern human studies are very limited. Because good safety and effectiveness data are lacking, it is best used cautiously and avoided in pregnancy and breastfeeding. Talk with your pharmacist or doctor before trying it, especially if you have a health condition or take medications.

Pilosella officinarum · Asteraceae · Aerial parts (leaves, flowers, and stems), usually the whole flowering herb · Tea (infusion), liquid extract or tincture, dried herb, capsules

An interaction check asks whether these two react with each other — it does not ask whether Mouse-ear Hawkweed is a good idea for someone in your situation. Here is what our Mouse-ear Hawkweed record says about it on its own.

Mouse-ear Hawkweed: dosing

There is no established standard dose for mouse-ear hawkweed. Traditional use has involved teas made from the dried herb and liquid extracts or tinctures, but reliable, science-based dosing is not available.If you choose to use a product, follow the directions on the label and do not exceed the suggested amount.

From our Mouse-ear Hawkweed monograph — the full record covers uses, side effects and every documented interaction.

Read the full Mouse-ear Hawkweed monograph & all interactions
Medication

About Idelalisib

What Is Idelalisib Used For?

Brand name: Zydelig

Zydelig (idelalisib) is approved to treat relapsed chronic lymphocytic leukemia (CLL) — a cancer of the blood and bone marrow — when used together with rituximab. It is specifically for patients who have already received treatment and for whom rituximab alone would be appropriate due to other health conditions.

Zydelig is not approved or recommended as a first-line (initial) treatment for CLL or any other cancer, including small lymphocytic lymphoma (SLL) or follicular lymphoma (FL). It is also not approved in combination with bendamustine and rituximab, or with rituximab alone, for FL, SLL, or other slow-growing non-Hodgkin lymphomas.

Most-Reported Side Effects for Idelalisib

From FAERS, the FDA’s public side-effect reporting system (7,040 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Disease progression 1,225 reports
Diarrhea 771 reports
Pneumonia 437 reports
Fever 375 reports
Fatigue 301 reports
See full Idelalisib drug information
Keep checking

Other Drugs & Mouse-ear Hawkweed

Browse every other medication we’ve checked against Mouse-ear Hawkweed — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Mouse-ear Hawkweed References

The 3 sources that drive our Mouse-ear Hawkweed monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Mouse-ear Hawkweed is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Hawkweed (Hieracium) information — MedlinePlus Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source
  3. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Mouse-ear Hawkweed and Idelalisib Together: Common Questions

Is it safe to take Mouse-ear Hawkweed with Idelalisib?
We do not list a known interaction between Mouse-ear Hawkweed and Idelalisib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Idelalisib interact with any supplements?
Yes. Idelalisib has documented interactions with 143 supplements in our database — Mouse-ear Hawkweed is not one of them. The Idelalisib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Idelalisib and Mouse-ear Hawkweed?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.