Drug & supplement interaction

New Jersey Tea + Penicillamine

Penicillamine brand names: Cuprimine, Depen Titratable.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between New Jersey Tea and Penicillamine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Penicillamine states a food rule worth keeping to.

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Interaction report

New Jersey Tea and Penicillamine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Penicillamine and New Jersey Tea in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for New Jersey Tea at all — not against Penicillamine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

New Jersey Tea safety at a glance

New Jersey Tea overall Not established Little modern safety data exists, so use cautiously and under professional guidance.
Pregnancy Avoid No reliable safety data in pregnancy, so it is best avoided.
Breastfeeding Avoid No reliable safety data while breastfeeding, so it is best avoided.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Penicillamine and New Jersey Tea? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Penicillamine’s Own FDA Label Lists

This is not an interaction — none of it involves New Jersey Tea. These are the most notable effects listed in the ADVERSE REACTIONS section of Penicillamine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Muscle weakness Worth acting on
  • Bleeding in the gut Worth acting on
  • Low blood sugar Worth acting on
  • Blood clots Worth acting on
  • Pancreatitis Worth acting on
  • Wheezing Worth acting on
  • A severe skin reaction Worth acting on
  • A low platelet count Worth acting on
  • Kidney problems Worth acting on
  • Anemia Worth acting on

Showing the 10 most notable of 26 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Penicillamine. Read the label on DailyMed › Where a percentage is shown, it is the share of 917 voluntary FDA FAERS reports for Penicillamine that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. New Jersey Tea’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no New Jersey Tea side to compare — that is a limit of the record, not a statement that New Jersey Tea has no side effects.

How to take them

Some Penicillamine Products Have a Food Rule — New Jersey Tea Should Not Break It

At least one FDA label for a product containing Penicillamine says to take it on an empty stomach. Most supplements — New Jersey Tea included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Penicillamine on its own and move New Jersey Tea to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Penicillamine products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

DOSAGE AND ADMINISTRATION In all patients receiving penicillamine, it is important that CUPRIMINE be given on an empty stomach, at least one hour before meals or two hours after meals, and at least one hour apart from any other drug, food, or milk.

From the Dosage and Administration section of the FDA label we read for Penicillamine — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Penicillamine

This page covers New Jersey Tea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Penicillamine page lists 26 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Siberian Cocklebur (major), Aristolochia (moderate) and Coffee Charcoal (moderate).

By severity: 3 major · 13 moderate · 10 minor.

From our pharmacist’s overview on the Penicillamine page

“People take penicillamine (Cuprimine, Depen) for demanding conditions, Wilson's disease, rheumatoid arthritis, cystinuria, and its 26 supplement interactions are not a list to skim, three of them rated major. Seventeen ingredients can keep an oral dose from being fully absorbed, activated charcoal chief among them, and six more can str…”

Reviewed by 2 · Jul 18, 2026

Open the Penicillamine interaction page

One more smart check

Taking New Jersey Tea as Part of a Dietary Supplement Product? Check It for Interactions

We hold 127 real supplement products containing New Jersey Tea, each one broken down to its full ingredient list — and combination products often carry several ingredients besides New Jersey Tea. Even though New Jersey Tea itself has no known interaction with Penicillamine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where New Jersey Tea and Penicillamine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement New Jersey Tea
Steady interest

#919 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Penicillamine
Steady interest

#2,400 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. New Jersey Tea is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every New Jersey Tea reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The New Jersey Tea and Penicillamine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About New Jersey Tea

What is New Jersey Tea?

  • Sore throat and mouth/gum irritation
  • Caffeine-free herbal tea
  • Cough and respiratory complaints
  • Traditional support for swollen lymph nodes
  • Mild astringent for minor bleeding

New Jersey Tea is a North American shrub whose leaves were historically brewed as a caffeine-free tea and used in folk medicine for sore throats and other complaints. There is very little modern scientific research to confirm any health benefit, so it should be viewed as a traditional remedy rather than a proven treatment. If you want to try it, talk with a pharmacist or doctor first, and avoid it during pregnancy and breastfeeding.

Ceanothus americanus · Rhamnaceae · Leaves and root (and root bark) · Tea (dried leaves), tincture, dried root preparations

An interaction check asks whether these two react with each other — it does not ask whether New Jersey Tea is a good idea for someone in your situation. Here is what our New Jersey Tea record says about it on its own.

New Jersey Tea: dosing

There is no established or standardized dose for New Jersey Tea. It has not been studied enough to know a safe and effective amount.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our New Jersey Tea monograph — the full record covers uses, side effects and every documented interaction.

Read the full New Jersey Tea monograph & all interactions
Medication

About Penicillamine

What Is Penicillamine Used For?

Brand names: Cuprimine, Depen Titratable

Penicillamine is used for three distinct conditions. It treats Wilson's disease — a rare genetic disorder in which the body accumulates dangerous levels of copper — by binding to the excess copper and helping the body remove it. It also treats cystinuria, a condition where the amino acid cystine builds up and forms painful kidney stones, by converting cystine into a more soluble form that the body can excrete more easily.

For patients with severe, active rheumatoid arthritis who have not responded adequately to conventional therapies, penicillamine (available as Aagylur, Cuprimine, Depen, and other products) may be used to help suppress disease activity and reduce joint pain, tenderness, and swelling.

See full Penicillamine drug information
Keep checking

Other Drugs & New Jersey Tea

Browse every other medication we’ve checked against New Jersey Tea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked New Jersey Tea against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full New Jersey Tea list.

See the full New Jersey Tea interactions page
See every supplement checked against Penicillamine, ranked by severity
Evidence & sources

New Jersey Tea References

The 1 sources that drive our New Jersey Tea monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. New Jersey Tea is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking New Jersey Tea and Penicillamine Together: Common Questions

Is it safe to take New Jersey Tea with Penicillamine?
We do not list a known interaction between New Jersey Tea and Penicillamine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take New Jersey Tea and Penicillamine at the same time of day?
At least one FDA label for a product containing Penicillamine says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Penicillamine on its own and move New Jersey Tea to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Penicillamine interact with any supplements?
Yes. Penicillamine has documented interactions with 26 supplements in our database — New Jersey Tea is not one of them. The Penicillamine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

New Jersey Tea monograph Uses, safety profile, and every drug interaction in one place Penicillamine drug information The full plain-English guide to this medication Penicillamine supplement interactions Every supplement checked against Penicillamine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Penicillamine and New Jersey Tea?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.