Drug & supplement interaction

Oriental Arborvitae + Tofacitinib

Tofacitinib brand names: Xeljanz, Xeljanz XR.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Oriental Arborvitae and Tofacitinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Oriental Arborvitae and Tofacitinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tofacitinib and Oriental Arborvitae in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Oriental Arborvitae at all — not against Tofacitinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Oriental Arborvitae safety at a glance

Oriental Arborvita... overall Use caution Some plant parts and oils can be toxic, and human safety data are limited.
Pregnancy Possibly Unsafe When the leafy twig is used orally during pregnancy. Oriental arborvitae contains thujone. Thujone might stimulate uterine activity; avoid using. There is insuf... Read the full pregnancy detail
Breastfeeding Avoid No reliable safety information, so it is best avoided while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tofacitinib and Oriental Arborvitae? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Oriental Arborvitae Itself Has Been Linked To

This is not an interaction — nothing below involves Tofacitinib. It is the side-effect record for Oriental Arborvitae on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Oriental Arborvitae, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • Hallucinations / Kidney problems Worth acting on Additional detail

    “Orally, taking oriental arborvitae long-term or at high doses might cause adverse effects due to the thujone constituent. Thujone-containing herbs can cause restlessness, vomiting, dizziness, tremors, kidney damage, hallucinations, and convulsions when used long-term or at high doses. Thujone intoxication can cause psychoactivity similar to tetrahydrocannibinol, the active constituent in marijuana. (12).”

    Oriental Arborvitae · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  • Seizures Worth acting on Additional detail

    “Orally, thujone-containing herbs such as oriental arborvitae may cause dizziness and convulsions when used long-term or at high doses (12).”

    Oriental Arborvitae · Natural Medicines adverse-effect record, reported in vertigo.

    1 source cited
    1. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  • Anxiety or restlessness Additional detail

    Recorded for Oriental Arborvitae in the same Natural Medicines adverse-effect record shown under Hallucinations / Kidney problems above.

  • Dizziness Additional detail

    Recorded for Oriental Arborvitae in the same Natural Medicines adverse-effect record shown under Hallucinations / Kidney problems above.

  • Vomiting Additional detail

    “Orally, thujone-containing herbs such as oriental arborvitae may cause vomiting when used long-term or at high doses (12).”

    Oriental Arborvitae · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

Everything above comes from the Natural Medicines adverse-effect record for Oriental Arborvitae — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Tofacitinib’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Tofacitinib column appears here.

Special populations

Oriental Arborvitae in Pregnancy & Breastfeeding

Pregnancy Possibly Unsafe

When the leafy twig is used orally during pregnancy. Oriental arborvitae contains thujone. Thujone might stimulate uterine activity; avoid using. There is insufficient reliable information available about the safety of oriental arborvitae when used topically during pregnancy; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Tofacitinib

This page covers Oriental Arborvitae only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tofacitinib page lists 184 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Active Hexose Correlated Compound (ahcc) (moderate).

By severity: 3 major · 143 moderate · 38 minor.

From our pharmacist’s overview on the Tofacitinib page

“Supplements deserve genuine care alongside tofacitinib (Xeljanz, Xeljanz XR), a medicine that deliberately dials down the immune system to control conditions like rheumatoid arthritis and ulcerative colitis. Most of the interactions on this page run through the liver enzymes that clear the drug, meaning an herb can push its blood level…”

Reviewed by 2 · Jul 18, 2026

Open the Tofacitinib interaction page

One more smart check

Taking Oriental Arborvitae as Part of a Dietary Supplement Product? Check It for Interactions

We hold 76 real supplement products containing Oriental Arborvitae, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Oriental Arborvitae. Even though Oriental Arborvitae itself has no known interaction with Tofacitinib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Oriental Arborvitae and Tofacitinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Oriental Arborvitae
Steady interest

#1,081 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tofacitinib
Top half

#1,406 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Oriental Arborvitae reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Oriental Arborvitae and Tofacitinib records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Oriental Arborvitae

What is Oriental Arborvitae?

Oriental Arborvitae
  • Insomnia and restlessness
  • Constipation (seeds)
  • Hair loss and scalp health (topical)
  • Bleeding and heavy menstruation (traditional)
  • Cough and respiratory complaints

Oriental Arborvitae is an evergreen conifer used in Traditional Chinese Medicine, where the seeds (Bai Zi Ren) are taken to calm the mind and ease constipation, and the leaves (Ce Bai Ye) are used for bleeding and hair loss. Solid human evidence for these uses is limited, and parts of the plant can be toxic if misused. Talk with a pharmacist or doctor before trying it, and avoid it in pregnancy.

Platycladus orientalis · Cupressaceae · Seeds (Bai Zi Ren) and leaves/twigs (Ce Bai Ye) · Dried seeds, dried leaf, decoctions (teas), powders, capsules, and topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Oriental Arborvitae is a good idea for someone in your situation. Here is what our Oriental Arborvitae record says about it on its own.

Oriental Arborvitae: dosing

There is no well-established standardized dose for Oriental Arborvitae as a supplement. In Traditional Chinese Medicine, the seeds and leaves are used in specific amounts within formulas prepared by a trained practitioner, and the right amount depends on the part used and the preparation.If you choose to use a commercial product, follow the directions on the label and do not exceed them. Never ingest the concentrated essential oil unless directed by a qualified professional.

From our Oriental Arborvitae monograph — the full record covers uses, side effects and every documented interaction.

Read the full Oriental Arborvitae monograph & all interactions
Medication

About Tofacitinib

What Is Tofacitinib Used For?

Brand names: Xeljanz, Xeljanz XR

  • Tofacitinib is used alone or with other medications to treat rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function) in adults who are unable to take or did not respond to one or more tumor necrosis factor (TNF) inhibitor medication(s). It is also used to treat psoriatic arthritis (a condition that causes joint pain and swelling and scales on the skin) in adults who are unable to take or did not respond to or tolerate one or more TNF inhibitor medication(s). Tofacitinib is used to treat ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum) in adults who are unable to take or who did not respond to one or more TNF inhibitor medication(s). It is also used to treat polyarticular juvenile idiopathic arthritis (PJIA; a type of childhood arthritis that affects five or more joints during the first six months of the condition, causing pain, swelling, and loss of function) in children 2 years and older who are unable to take or who did not respond to one or more TNF inhibitor medication(s). Tofacitinib is in a class of medications called Janus kinase (JAK) inhibitors. It works by decreasing the activity of the immune system.

See full Tofacitinib drug information
Keep checking

Other Drugs & Oriental Arborvitae

Browse every other medication we’ve checked against Oriental Arborvitae — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Oriental Arborvitae against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Oriental Arborvitae list.

See the full Oriental Arborvitae interactions page
See every supplement checked against Tofacitinib, ranked by severity
Evidence & sources

Oriental Arborvitae References

The 2 references that drive our Oriental Arborvitae monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Oriental Arborvitae and Tofacitinib Together: Common Questions

Is it safe to take Oriental Arborvitae with Tofacitinib?
We do not list a known interaction between Oriental Arborvitae and Tofacitinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Tofacitinib interact with any supplements?
Yes. Tofacitinib has documented interactions with 184 supplements in our database — Oriental Arborvitae is not one of them. The Tofacitinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Oriental Arborvitae monograph Uses, safety profile, and every drug interaction in one place Tofacitinib drug information The full plain-English guide to this medication Tofacitinib supplement interactions Every supplement checked against Tofacitinib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Tofacitinib and Oriental Arborvitae?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.