Drug & supplement interaction

Pellitory + Atazanavir

Atazanavir brand name: Reyataz.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Pellitory and Atazanavir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Atazanavir states a food rule worth keeping to.

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Interaction report

Pellitory and Atazanavir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Atazanavir and Pellitory in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Pellitory at all — not against Atazanavir, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Pellitory safety at a glance

Pellitory overall Use caution Limited safety data exist, and it may cause mouth irritation or allergic reactions.
Pregnancy Avoid Not enough safety information is available, so it is best avoided.
Breastfeeding Avoid There is no reliable safety data during breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Atazanavir and Pellitory? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Atazanavir’s Own FDA Label Lists

This is not an interaction — none of it involves Pellitory. These are the most notable effects listed in the ADVERSE REACTIONS section of Atazanavir’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 4 of them are worth acting on rather than waiting out — marked below.

  • Low mood Worth acting on mentioned in 13.3% of FDA reports for Atazanavir
  • Kidney stones Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Kidney problems Worth acting on
  • Muscle pain
  • Trouble sleeping
  • Fever
  • Stomach pain
  • Dizziness
  • Diarrhea

Showing the 10 most notable of 14 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Atazanavir. Read the label on DailyMed › Where a percentage is shown, it is the share of 14,470 voluntary FDA FAERS reports for Atazanavir that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Pellitory’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Pellitory side to compare — that is a limit of the record, not a statement that Pellitory has no side effects.

How to take them

Some Atazanavir Products Have a Food Rule — Pellitory Should Not Break It

At least one FDA label for a product containing Atazanavir says to take it with food. If you take Pellitory on an empty stomach out of habit, keep them separate — and take Atazanavir with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Atazanavir products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

b For adult patients who cannot swallow the capsules, REYATAZ oral powder is taken once daily with food at the same recommended adult dosage as the capsules along with ritonavir.

From the Dosage and Administration section of the FDA label we read for Atazanavir — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Atazanavir

This page covers Pellitory only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Atazanavir page lists 152 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 107 moderate · 42 minor.

From our pharmacist’s overview on the Atazanavir page

“Atazanavir (Reyataz) treats HIV, and keeping its blood level steady is what stands between viral control and drug resistance, so I read this list with genuine care. Of the 152 supplement and herbal ingredients on file, three carry a major rating: St.”

Reviewed by 2 · Jul 18, 2026

Open the Atazanavir interaction page

One more smart check

Taking Pellitory as Part of a Dietary Supplement Product? Check It for Interactions

We hold 36 real supplement products containing Pellitory, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Pellitory. Even though Pellitory itself has no known interaction with Atazanavir, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Pellitory and Atazanavir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Pellitory
Top half

#587 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Atazanavir
Top half

#1,291 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Pellitory reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Pellitory and Atazanavir records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Pellitory

What is Pellitory?

  • Toothache and oral discomfort
  • Increasing saliva flow
  • Sluggish digestion
  • Traditional tonic in some folk medicine systems

Pellitory (often Anacyclus pyrethrum, the root traditionally called 'pellitory of Spain') is an herb chiefly known in folk and traditional medicine for numbing toothache and stimulating saliva. Human evidence for its benefits is very limited, so it should be viewed as a traditional remedy rather than a proven treatment. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Anacyclus pyrethrum · Asteraceae · Root · Powder, root extract, tinctures, tooth powders and mouthwashes

An interaction check asks whether these two react with each other — it does not ask whether Pellitory is a good idea for someone in your situation. Here is what our Pellitory record says about it on its own.

Pellitory: dosing

There is no well-established, standardized dose for pellitory, and product strengths vary widely.

From our Pellitory monograph — the full record covers uses, side effects and every documented interaction.

Read the full Pellitory monograph & all interactions
Medication

About Atazanavir

What Is Atazanavir Used For?

Brand name: Reyataz

Atazanavir capsules are used together with other antiretroviral medicines to treat HIV-1 infection in adults and in children 6 years and older who weigh at least 15 kg (about 33 lbs).

Reyataz — available as capsules and as an oral powder — is also approved for HIV-1 treatment in adults and in children as young as 3 months who weigh at least 5 kg (about 11 lbs). Reyataz oral powder must always be taken with ritonavir and food, and is not for use in children weighing less than 5 kg.

Most-Reported Side Effects for Atazanavir

From FAERS, the FDA’s public side-effect reporting system (14,470 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Depression 1,318 reports
Foetal exposure during pregnancy 1,048 reports
Anxiety 878 reports
Emotional distress 660 reports
Anhedonia 601 reports
See full Atazanavir drug information
Keep checking

Other Drugs & Pellitory

Browse every other medication we’ve checked against Pellitory — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Pellitory against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Pellitory list.

See the full Pellitory interactions page
See every supplement checked against Atazanavir, ranked by severity
Evidence & sources

Pellitory References

The 1 references that drive our Pellitory monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Pellitory and Atazanavir Together: Common Questions

Is it safe to take Pellitory with Atazanavir?
We do not list a known interaction between Pellitory and Atazanavir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Pellitory and Atazanavir at the same time of day?
At least one FDA label for a product containing Atazanavir says to take it with food. If you take Pellitory on an empty stomach out of habit, keep them separate and take Atazanavir with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Atazanavir products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Atazanavir interact with any supplements?
Yes. Atazanavir has documented interactions with 152 supplements in our database — Pellitory is not one of them. The Atazanavir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Pellitory monograph Uses, safety profile, and every drug interaction in one place Atazanavir drug information The full plain-English guide to this medication Atazanavir supplement interactions Every supplement checked against Atazanavir, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Atazanavir and Pellitory?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.