Drug & supplement interaction

Prenatal Vitamins + Daprodustat

Daprodustat brand name: Jesduvroq.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Prenatal Vitamins and Daprodustat in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Prenatal Vitamins and Daprodustat

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Daprodustat and Prenatal Vitamins in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Prenatal Vitamins at all — not against Daprodustat, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Prenatal Vitamins safety at a glance

Prenatal Vitamins overall Generally safe Generally safe when taken as directed, though they can cause mild stomach upset or constipation.
Pregnancy Likely Safe When used orally. Prenatal vitamins contain many different minerals, vitamins, and sometimes other dietary supplement ingredients. Each individual ingredient ha... Read the full pregnancy detail
Breastfeeding Possibly Safe When used orally. Prenatal vitamins usually do not contain ingredients in amounts that exceed the tolerable upper intake level (UL). The UL is the highest level... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Daprodustat and Prenatal Vitamins? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Daprodustat’s Own FDA Label Lists

This is not an interaction — none of it involves Prenatal Vitamins. These are the most notable effects listed in the ADVERSE REACTIONS section of Daprodustat’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 8 of them are worth acting on rather than waiting out — marked below.

  • Heart failure Worth acting on mentioned in 4.9% of FDA reports for Daprodustat
  • A heart attack Worth acting on
  • Blood clots Worth acting on
  • Kidney problems Worth acting on mentioned in 4.9% of FDA reports for Daprodustat
  • Anemia Worth acting on mentioned in 5.1% of FDA reports for Daprodustat
  • Raised blood pressure Worth acting on
  • Hives Worth acting on
  • An allergic reaction Worth acting on
  • Stomach upset
  • Stomach pain

Showing the 10 most notable of 12 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Daprodustat. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,756 voluntary FDA FAERS reports for Daprodustat that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Prenatal Vitamins’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Prenatal Vitamins side to compare — that is a limit of the record, not a statement that Prenatal Vitamins has no side effects.

Special populations

Prenatal Vitamins in Pregnancy & Breastfeeding

Pregnancy Likely Safe

When used orally. Prenatal vitamins contain many different minerals, vitamins, and sometimes other dietary supplement ingredients. Each individual ingredient has a unique safety profile. Clinical studies evaluating prenatal vitamins show that prenatal vitamins are safe when used appropriately during pregnancy.

Lactation Possibly Safe

When used orally. Prenatal vitamins usually do not contain ingredients in amounts that exceed the tolerable upper intake level (UL). The UL is the highest level of nutrient intake that is unlikely to have a risk of adverse effects for most people, as determined by the Food and Nutrition Board and the National Academies of Science. Therefore, prenatal vitamins have apparent safety during lactation. However, high quality research assessing the safety of prenatal vitamins during lactation is lacking.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Daprodustat Is Prescribed For, and What Prenatal Vitamins Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Daprodustat is a prescription medicine with approved uses on its FDA label. Prenatal Vitamins is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Daprodustat is prescribed for: Jesduvroq (daprodustat) is approved to treat anemia due to chronic kidney disease (CKD) in adults who have been on dialysis for at least four months. It works by stimulating the body's own red blood cell production to reduce the need for blood transfusions. Important limits: Jesduvroq is not a substitute for emergency blood transfusions, and it is not approved for people with CKD who are not on dialysis. It has also not been shown to improve quality of life, fatigue, or overall well-being.

Prenatal Vitamins has been studied for:

  • Anemia Natural Medicines rates the evidence for Prenatal Vitamins: Possibly Effective Read what the research shows

    Prenatal Vitamins for anemia

    There is a higher requirement of dietary iron during pregnancy. The recommended dietary allowance (RDA) of iron during pregnancy is 27 mg daily. This daily requirement was calculated by accounting for the increased hemoglobin mass during pregnancy, increased iron requirement for deposition into the placenta and fetus, and other factors.

    2 sources cited
    1. 94811. Riley LE, Stark AR, Kilpatrick SJ, et al. Guidelines for Perinatal Care. 7th ed. Washington, DC: The American Academy of Pediatrics and the American College of Obstetricians and Gynecologists; 2012.
    2. 94595. Bentley S, Hermes A, Phillips D, Daoud YA, Hanna S. Comparative effectiveness of a prenatal medical food to prenatal vitamins on hemoglobin levels and adverse outcomes: a retrospective analysis. Clin Ther. 2011;33(2):204-10. PubMed

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Daprodustat on your own; if you are taking Prenatal Vitamins for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Prenatal Vitamins or Daprodustat

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Prenatal Vitamins or Daprodustat, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Daprodustat

This page covers Prenatal Vitamins only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Daprodustat page lists 28 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), African Wild Potato (moderate), Breadfruit (moderate), Cannabidiol (cbd) (moderate) and Coffee Charcoal (moderate).

By severity: 1 major · 16 moderate · 11 minor.

From our pharmacist’s overview on the Daprodustat page

“People taking daprodustat (Jesduvroq) for anemia from chronic kidney disease are often the same people using fiber for constipation or CBD for sleep, and this interaction list deserves genuine care. Of the 28 supplement ingredients on file, eleven may block CYP2C8, the enzyme that clears daprodustat, which could raise its levels beyond…”

Reviewed by 2 · Jul 18, 2026

Open the Daprodustat interaction page

How much people look this up

Where Prenatal Vitamins and Daprodustat Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Prenatal Vitamins
Steady interest

#1,189 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Daprodustat
Steady interest

#2,348 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Prenatal Vitamins reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Prenatal Vitamins and Daprodustat records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Prenatal Vitamins

What is Prenatal Vitamins?

  • Nutritional support before and during pregnancy
  • Preventing neural tube defects (folic acid)
  • Supporting healthy fetal development
  • Preventing iron-deficiency anemia in pregnancy
  • Support during breastfeeding

Prenatal vitamins are multivitamin-mineral supplements designed to fill nutritional gaps before and during pregnancy and while breastfeeding, with folic acid and iron being especially important. They are widely recommended by doctors, but they do not replace a healthy diet, and you should choose a product and dose with guidance from your pharmacist or doctor.

Tablets, capsules, soft gels, chewables, gummies, liquids

An interaction check asks whether these two react with each other — it does not ask whether Prenatal Vitamins is a good idea for someone in your situation. Here is what our Prenatal Vitamins record says about it on its own.

Prenatal Vitamins: dosing

There is no single "correct" prenatal vitamin, since products differ in their ingredients and amounts. Most are taken once daily, but some require more than one tablet or a separate DHA softgel.

From our Prenatal Vitamins monograph — the full record covers uses, side effects and every documented interaction.

Read the full Prenatal Vitamins monograph & all interactions
Medication

About Daprodustat

What Is Daprodustat Used For?

Brand name: Jesduvroq

Jesduvroq (daprodustat) is approved to treat anemia due to chronic kidney disease (CKD) in adults who have been on dialysis for at least four months. It works by stimulating the body's own red blood cell production to reduce the need for blood transfusions.

Important limits: Jesduvroq is not a substitute for emergency blood transfusions, and it is not approved for people with CKD who are not on dialysis. It has also not been shown to improve quality of life, fatigue, or overall well-being.

Most-Reported Side Effects for Daprodustat

From FAERS, the FDA’s public side-effect reporting system (1,878 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hospitalisation 276 reports
Haemoglobin decreased 94 reports
Renal impairment 91 reports
Cardiac failure 86 reports
Haemoglobin increased 77 reports
See full Daprodustat drug information
Keep checking

Other Drugs & Prenatal Vitamins

Browse every other medication we’ve checked against Prenatal Vitamins — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Prenatal Vitamins against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Prenatal Vitamins list.

See the full Prenatal Vitamins interactions page
See every supplement checked against Daprodustat, ranked by severity
Evidence & sources

Prenatal Vitamins References

The 18 references that drive our Prenatal Vitamins monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Dietary reference intakes (DRIs): estimated average requirements. Food and Nutrition Board, Institute of Medicine, National Academics. https://www.nal.usda.gov/sites/default/files/fnic_uploads//recommended_intakes_individuals.pdf Accessed July 24, 2017.
  2. Bentley S, Hermes A, Phillips D, Daoud YA, Hanna S. Comparative effectiveness of a prenatal medical food to prenatal vitamins on hemoglobin levels and adverse outcomes: a retrospective analysis. Clin Ther. 2011;33(2):204-10. PubMed
  3. Braun JM, Froehlich T, Kalkbrenner A. Brief report: are autistic-behaviors in children related to prenatal vitamin use and maternal whole blood folate concentrations? J Autism Dev Disord. 2014;44(10):2602-7. PubMed
  4. Dougan MM, Willett WC, Michels KB. Prenatal vitamin intake during pregnancy and offspring obesity. Int J Obes. 2015;39(1):69-74. PubMed
  5. Sauder KA, Starling AP, Shapiro AL, et al. Exploring the association between maternal prenatal multivitamin use and early infant growth: The Healthy Start Study. Pediatr Obes. 2016;11(5):434-41. PubMed
  6. Riley LE, Stark AR, Kilpatrick SJ, et al. Guidelines for Perinatal Care. 7th ed. Washington, DC: The American Academy of Pediatrics and the American College of Obstetricians and Gynecologists; 2012.
  7. Czeizel AE, Dudás I. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med. 1992;327(26):1832-5. PubMed
  8. Czeizel AE. Prevention of congenital abnormalities by periconceptional multivitamin supplementation. BMJ. 1993;306(6893):1645-8. PubMed
  9. Scholl TO, Hediger ML, Bendich A, et al. Use of multivitamin/mineral prenatal supplements: influence on the outcome of pregnancy. Am J Epidemiol. 1997;146(2):134-41. PubMed
  10. Goh YI, Bollano E, Einarson TR, Koren G. Prenatal multivitamin supplementation and rates of pediatric cancers: a meta-analysis. Clin Pharmacol Ther. 2007 May;81(5):685-91. PubMed
  11. Goh YI, Bollano E, Einarson TR, Koren G. Prenatal multivitamin supplementation and rates of congenital anomalies: a meta-analysis. J Obstet Gynaecol Can. 2006 Aug;28(8):680-9. Review. PubMed
  12. Balogun OO, da Silva Lopes K, Ota E, et al. Vitamin supplementation for preventing miscarriage. Cochrane Database Syst Rev. 2016 May 6;(5):CD004073. PubMed
  13. Dean SV, Lassi ZS, Imam AM, Bhutta ZA. Preconception care: nutritional risks and interventions. Reprod Health. 2014;11 Suppl 3:S3. PubMed
  14. Virk J, Liew Z, Olsen J, Nohr EA, Catov JM, Ritz B. Pre-conceptual and prenatal supplementary folic acid and multivitamin intake, behavioral problems, and hyperkinetic disorders: A study based on the Danish National Birth Cohort (DNBC). Nutr Neurosci. 201 PubMed
  15. Wolf HT, Hegaard HK, Huusom LD, Pinborg AB. Multivitamin use and adverse birth outcomes in high-income countries: a systematic review and meta-analysis. Am J Obstet Gynecol. 2017;217(4):404.e1-404.e30. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Prenatal Vitamins and Daprodustat Together: Common Questions

Is it safe to take Prenatal Vitamins with Daprodustat?
We do not list a known interaction between Prenatal Vitamins and Daprodustat. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Prenatal Vitamins and Daprodustat used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Prenatal Vitamins in each. That is a conversation for your prescriber, especially if Daprodustat is being adjusted to a target.
Does Daprodustat interact with any supplements?
Yes. Daprodustat has documented interactions with 28 supplements in our database — Prenatal Vitamins is not one of them. The Daprodustat interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Prenatal Vitamins monograph Uses, safety profile, and every drug interaction in one place Daprodustat drug information The full plain-English guide to this medication Daprodustat supplement interactions Every supplement checked against Daprodustat, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 18 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Daprodustat and Prenatal Vitamins?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.