Riboflavin + Aluminum Acetate
Aluminum Acetate brand name: Burow's Solution.
We found no known interaction between Riboflavin and Aluminum Acetate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Riboflavin and Aluminum Acetate
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Aluminum Acetate and Riboflavin in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Riboflavin safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Aluminum Acetate
Interactions in our licensed database are recorded against drug classes, not just single drug names. Aluminum Acetate is filed under a single classification — topical drugs. Riboflavin has documented interactions with 1 drug class — the most serious being tetracycline antibiotics (moderate) — and none of Aluminum Acetate’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Riboflavin Does Interact With Other Medications
Riboflavin has 20 moderate known drug interactions in our database — Aluminum Acetate isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Riboflavin
We haven’t checked that one against Riboflavin yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Riboflavin. Pick one to open its full report.
Riboflavin in Pregnancy & Breastfeeding
When used orally and appropriately in dietary amounts. A tolerable upper intake level (UL) has not been established.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Aluminum Acetate
This page covers Riboflavin only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Aluminum Acetate page lists 3 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).
By severity: 2 moderate · 1 minor.
From our pharmacist’s overview on the Aluminum Acetate page
“Aluminum acetate (Burow's Solution) is the soak or compress people reach for with weepy rashes, athlete's foot, or swimmer's ear, and its three supplement interactions on file all come down to what else touches that same patch of skin. None is rated major, and this is a list most people can handle with a little attention rather than al…”
Reviewed by 2 · Jul 18, 2026
Taking Riboflavin as Part of a Dietary Supplement Product? Check It for Interactions
We hold 18,014 real supplement products containing Riboflavin, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Riboflavin. Even though Riboflavin itself has no known interaction with Aluminum Acetate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Riboflavin and Aluminum Acetate Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#12 of 1,452 supplements looked up here in the last 7 days
#2,156 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Riboflavin reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Riboflavin and Aluminum Acetate records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Riboflavin
What is Riboflavin?
- Riboflavin deficiency
- Migraine prevention
- General energy and metabolism support
- Healthy skin and eyes
Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally very safe at typical doses, and the strongest evidence supports its use for treating deficiency, with some supportive (but not definitive) evidence for preventing migraines.
Vitamin (water-soluble B vitamin) · Tablets, capsules, softgels, multivitamins, B-complex products, fortified foods
An interaction check asks whether these two react with each other — it does not ask whether Riboflavin is a good idea for someone in your situation. Here is what our Riboflavin record says about it on its own.
Riboflavin: dosing
There is a recommended daily intake for riboflavin as a nutrient, and most people meet it through a normal diet. Do not assume that more is better.
From our Riboflavin monograph — the full record covers uses, side effects and every documented interaction.
About Aluminum Acetate
What Is Aluminum Acetate Used For?
Brand name: Burow's Solution
Aluminum acetate is applied to the skin to temporarily ease the itch, irritation, and discomfort of a range of common skin conditions. Most products — including Tricalm Hydrogel, TriCalm, and Dermeleve cream — are used for poison ivy, poison oak, poison sumac, insect bites, athlete's foot, and rashes caused by soaps, detergents, cosmetics, or jewelry.
Dermeleve cream also lists minor burns among its uses. Dermeleve Anti Itch Scalp Serum is specifically formulated for scalp itch and rashes from soaps, detergents, or cosmetics applied to the scalp. The ZO Skin Health powder products target rashes from soaps, detergents, cosmetics, or jewelry.
Most-Reported Side Effects for Aluminum Acetate
From FAERS, the FDA’s public side-effect reporting system (40 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Riboflavin
Browse every other medication we’ve checked against Riboflavin — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
20 interactions
- Doxycycline ›
- Minocycline ›
- Tetracycline ›
- Doxycycline Hyclate ›
- Minocycline Hydrochloride ›
- Retapamulin ›
- Chlortetracycline ›
- Demeclocycline ›
- Doripenem ›
- Doxycycline Monohydrate ›
- Doxycyline ›
- Eravacycline ›
- Omadacycline (iv) ›
- Omadacycline (oral) ›
- Oxytetracycline ›
- Tigecycline ›
- Amphotericin, Tetracycline ›
- Bismuth Subsalicylate, Metronidazole, Tetracycline ›
- Metronidazole, Tetracyline, Bismuth Subcitrate Potassium ›
- Oxytetracycline, Phenazopyridine, Sulfamethizole ›
No interaction 2,809 drugs checked — show the list
We also checked Riboflavin against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
- Bisoprolol ›
Showing the 60 most looked-up of 2,809 medications checked with no known interaction — see the full Riboflavin list.
Riboflavin References
The 5 references that drive our Riboflavin monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology 1998;50:466-70. PubMed
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Leeson LJ, Weidenheimer JF. Stability of tetracycline and riboflavin. J Pharm Sci. 1969;58(3):355-7. PubMed
- MacLennan, S. C., Wade, F. M., Forrest, K. M., Ratanayake, P. D., Fagan, E., and Antony, J. High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial. J Child Neurol. 2008;23(11):1300-1304.
- Dietary reference intakes (DRIs): estimated average requirements. Food and Nutrition Board, Institute of Medicine, National Academics. https://www.nal.usda.gov/sites/default/files/fnic_uploads//recommended_intakes_individuals.pdf Accessed July 24, 2017.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Riboflavin and Aluminum Acetate Together: Common Questions
Is it safe to take Riboflavin with Aluminum Acetate?
How was the Riboflavin and Aluminum Acetate combination checked?
Does Riboflavin interact with any other medications?
Does Aluminum Acetate interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.