Drug & supplement interaction

Rose Geranium Oil + Tafenoquine

Tafenoquine brand names: Krintafel, Arakoda.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Rose Geranium Oil and Tafenoquine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Tafenoquine states a food rule worth keeping to.

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Interaction report

Rose Geranium Oil and Tafenoquine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tafenoquine and Rose Geranium Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Rose Geranium Oil at all — not against Tafenoquine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Rose Geranium Oil safety at a glance

Rose Geranium Oil overall Use caution Generally considered safe for diluted topical or aromatherapy use, but it can irritate skin and should not be swallowed.
Pregnancy Avoid Safety is not well studied, so it is best to avoid medicinal use during pregnancy.
Breastfeeding Avoid There is not enough reliable information, so avoid medicinal use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tafenoquine and Rose Geranium Oil? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Rose Geranium Oil Itself Has Been Linked To

This is not an interaction — nothing below involves Tafenoquine. It is the side-effect record for Rose Geranium Oil on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Rose Geranium Oil, this list is the first place to look.

  • A skin rash Additional detail

    “Topically, rose geranium oil has been associated with reports of dermatitis in hypersensitive individuals and burning sensations when applied to the face.”

    Rose Geranium Oil · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 16653. Greenway FL, Frome BM, Engels TM. Temporary relief of postherpetic neuralgia pain with topical geranium oil. Am J Med 2003;115:586-7. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Rose Geranium Oil — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Tafenoquine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Tafenoquine column appears here.

How to take them

Some Tafenoquine Products Have a Food Rule — Rose Geranium Oil Should Not Break It

At least one FDA label for a product containing Tafenoquine says to take it with food. If you take Rose Geranium Oil on an empty stomach out of habit, keep them separate — and take Tafenoquine with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Tafenoquine products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

( 2.1 ) Regimen Name Timing Dosage Loading regimen For each of the 3 days before travel to a malarious area 200 mg (2 of the 100 mg tablets) once daily for 3 days Maintenance regimen While in the malarious area 200 mg (2 of the 100 mg tablets) once weekly – start 7 days after the last loading regimen dose Terminal prophylaxis regimen In the week following exit from the malarious area 200 mg (2 of

From the Dosage and Administration section of the FDA label we read for Tafenoquine — where that label names a specific product, the instruction is that product's. See the Tafenoquine drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Tafenoquine

This page covers Rose Geranium Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tafenoquine page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Tafenoquine page

“Tafenoquine (Krintafel, Arakoda) protects against malaria, including the relapsing kind that hides in the liver, and every supplement known to interact with it threatens the same thing, how much of the pill actually reaches your blood. That deserves genuine care, since a partly absorbed antimalarial can let parasites survive and resurf…”

Reviewed by 2 · Jul 18, 2026

Open the Tafenoquine interaction page

One more smart check

Taking Rose Geranium Oil as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Rose Geranium Oil, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Rose Geranium Oil. Even though Rose Geranium Oil itself has no known interaction with Tafenoquine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Rose Geranium Oil and Tafenoquine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Rose Geranium Oil
Steady interest

#1,166 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tafenoquine
Steady interest

#2,703 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Rose Geranium Oil reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Rose Geranium Oil and Tafenoquine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Rose Geranium Oil

What is Rose Geranium Oil?

  • Skin care and complexion
  • Aromatherapy for stress and mood
  • Insect and tick repellent
  • Minor wound and skin soothing
  • Fragrance

Rose geranium oil is an essential oil distilled from the leaves of Pelargonium graveolens, used mainly in aromatherapy, skincare, and as a natural fragrance. High-quality human evidence for medical benefits is limited, and like all essential oils it must be diluted before skin use and never swallowed. Talk to a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have sensitive skin.

Pelargonium graveolens · Geraniaceae · Leaves and stems (steam-distilled essential oil) · Essential oil, diluted topical blends, aromatherapy products, soaps and skincare items

An interaction check asks whether these two react with each other — it does not ask whether Rose Geranium Oil is a good idea for someone in your situation. Here is what our Rose Geranium Oil record says about it on its own.

Rose Geranium Oil: dosing

There is no established standardized medical dose for rose geranium oil. It is used mainly topically (in diluted form) or by inhaling its scent, not by mouth.For skin use, essential oils are typically mixed at a low concentration in a carrier oil, but you should follow the specific instructions on your product label.

From our Rose Geranium Oil monograph — the full record covers uses, side effects and every documented interaction.

Read the full Rose Geranium Oil monograph & all interactions
Medication

About Tafenoquine

What Is Tafenoquine Used For?

Brand names: Krintafel, Arakoda

Tafenoquine is used for two distinct purposes depending on the product. Arakoda and Kodatef are used for malaria prophylaxis — that is, preventing malaria in adults 18 and older who are traveling to or living in areas where malaria is present.

Krintafel is used for the radical cure of Plasmodium vivax malaria — meaning it prevents the malaria parasite from coming back (relapsing) in patients 16 and older who are already being treated with chloroquine for an active P. vivax infection. Krintafel is not used to treat an active malaria attack on its own, and it should only be used alongside chloroquine, not other antimalarials.

Most-Reported Side Effects for Tafenoquine

From FAERS, the FDA’s public side-effect reporting system (70 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Depression 20 reports
Anxiety 18 reports
Post-traumatic stress disorder 15 reports
Anger 14 reports
Nausea 14 reports
See full Tafenoquine drug information
Keep checking

Other Drugs & Rose Geranium Oil

Browse every other medication we’ve checked against Rose Geranium Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Rose Geranium Oil References

The 1 references that drive our Rose Geranium Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Greenway FL, Frome BM, Engels TM. Temporary relief of postherpetic neuralgia pain with topical geranium oil. Am J Med 2003;115:586-7. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Rose Geranium Oil and Tafenoquine Together: Common Questions

Is it safe to take Rose Geranium Oil with Tafenoquine?
We do not list a known interaction between Rose Geranium Oil and Tafenoquine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Rose Geranium Oil and Tafenoquine at the same time of day?
At least one FDA label for a product containing Tafenoquine says to take it with food. If you take Rose Geranium Oil on an empty stomach out of habit, keep them separate and take Tafenoquine with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Tafenoquine products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Tafenoquine interact with any supplements?
Yes. Tafenoquine has documented interactions with 17 supplements in our database — Rose Geranium Oil is not one of them. The Tafenoquine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Tafenoquine and Rose Geranium Oil?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.