Drug & supplement interaction

Rusty-leaved Rhododendron + Acalabrutinib

Acalabrutinib brand name: Calquence.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Rusty-leaved Rhododendron and Acalabrutinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Rusty-leaved Rhododendron and Acalabrutinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Acalabrutinib and Rusty-leaved Rhododendron in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Rusty-leaved Rhododendron at all — not against Acalabrutinib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Rusty-leaved Rhododendron safety at a glance

Rusty-leaved Rhodo... overall Use caution Limited safety data and risk of toxic look-alike species mean it should be used cautiously.
Pregnancy Possibly Unsafe When used orally. Rusty-leaved rhododendron might be poisonous; avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally. Rusty-leaved rhododendron might be poisonous; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Acalabrutinib and Rusty-leaved Rhododendron? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Rusty-leaved Rhododendron and Acalabrutinib May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Dizziness / Vomiting / Nausea Additional detail

    Rusty-leaved Rhododendron

    “There is currently no information on the adverse effects of rusty-leaved rhododendron. A related species, Rhododendron ponticum, can cause weakness, dizziness, nausea, vomiting, hypotension, bradycardia, transient A-V dissociation and blurred vision (18,3496).”

    Rusty-leaved Rhododendron · Natural Medicines adverse-effect record, reported in epilepsy.

    5 sources cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    2. 3496. Biberoglu S, Biberoglu K, Komsuoglu B. Mad honey. [Letter to the Editor] JAMA 1988;259:1943.
    3. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    4. 3477. Furbee B, Wermuth M. Life-threatening plant poisoning. Crit Care Clin 1997;13:849-88. PubMed
    5. 100643. Louis A, Petereit F, Lechtenberg M, Deters A, Hensel A. Phytochemical characterization of Rhododendron ferrugineum and in vitro assessment of an aqueous extract on cell toxicity. Planta Med 2010;76(14):1550-7. doi: 10.1055/s-0029-1241016.

    Acalabrutinib

    Listed in the ADVERSE REACTIONS section of the FDA label for Acalabrutinib. Read the label on DailyMed ›

Reported for Rusty-leaved Rhododendron but not commonly for Acalabrutinib: blurred vision, a slow heartbeat, low blood pressure and fainting.

Effects for Acalabrutinib come from the ADVERSE REACTIONS section of its FDA label; effects for Rusty-leaved Rhododendron come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Rusty-leaved Rhododendron in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally. Rusty-leaved rhododendron might be poisonous; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Acalabrutinib

This page covers Rusty-leaved Rhododendron only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Acalabrutinib page lists 144 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 103 moderate · 38 minor.

From our pharmacist’s overview on the Acalabrutinib page

“For anyone taking acalabrutinib (Calquence) for chronic lymphocytic leukemia or lymphoma, the supplement list below deserves genuine scrutiny. Of 144 ingredients on file, nearly all act on CYP3A4, the liver enzyme that clears the drug, or on P-glycoprotein, a transporter that moves it, so they can push its level too high or leave too l…”

Reviewed by 2 · Jul 18, 2026

Open the Acalabrutinib interaction page

How much people look this up

Where Rusty-leaved Rhododendron and Acalabrutinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Rusty-leaved Rhododendron
Steady interest

#839 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Acalabrutinib
Top half

#1,270 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Rusty-leaved Rhododendron reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Rusty-leaved Rhododendron and Acalabrutinib records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Rusty-leaved Rhododendron

What is Rusty-leaved Rhododendron?

  • Joint and muscle pain
  • Gout and rheumatic complaints
  • High blood pressure (folk use)
  • General aches and pains

Rusty-leaved rhododendron is an alpine shrub used in traditional European medicine for pain and rheumatic complaints, but there is very little human research to support these uses. Because rhododendron species can contain toxic compounds and are easily confused with one another, it is best to use this plant only with professional guidance and to avoid it during pregnancy and breastfeeding.

Rhododendron ferrugineum · Ericaceae · Leaves and flowers · Tea, tincture, dried herb, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Rusty-leaved Rhododendron is a good idea for someone in your situation. Here is what our Rusty-leaved Rhododendron record says about it on its own.

Rusty-leaved Rhododendron: dosing

There is no established or standardized safe dose for rusty-leaved rhododendron. Because the plant can contain toxic compounds and because amounts vary from plant to plant, it is not possible to recommend a specific dose.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our Rusty-leaved Rhododendron monograph — the full record covers uses, side effects and every documented interaction.

Read the full Rusty-leaved Rhododendron monograph & all interactions
Medication

About Acalabrutinib

What Is Acalabrutinib Used For?

Brand name: Calquence

Calquence is used to treat adults with mantle cell lymphoma (MCL) — either newly diagnosed (in combination with bendamustine and rituximab, for patients who are not candidates for a stem cell transplant) or previously treated (after at least one prior therapy). It is also used to treat adults with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).

Both the capsule and tablet forms of Calquence are approved for all three of these uses. The specific combination regimen and treatment schedule depend on the condition being treated and what other medicines are used alongside it — your care team will map that out for you.

See full Acalabrutinib drug information
Keep checking

Other Drugs & Rusty-leaved Rhododendron

Browse every other medication we’ve checked against Rusty-leaved Rhododendron — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Rusty-leaved Rhododendron References

The 6 references that drive our Rusty-leaved Rhododendron monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Furbee B, Wermuth M. Life-threatening plant poisoning. Crit Care Clin 1997;13:849-88. PubMed
  5. Biberoglu S, Biberoglu K, Komsuoglu B. Mad honey. [Letter to the Editor] JAMA 1988;259:1943.
  6. Louis A, Petereit F, Lechtenberg M, Deters A, Hensel A. Phytochemical characterization of Rhododendron ferrugineum and in vitro assessment of an aqueous extract on cell toxicity. Planta Med 2010;76(14):1550-7. doi: 10.1055/s-0029-1241016.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Rusty-leaved Rhododendron and Acalabrutinib Together: Common Questions

Is it safe to take Rusty-leaved Rhododendron with Acalabrutinib?
We do not list a known interaction between Rusty-leaved Rhododendron and Acalabrutinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Rusty-leaved Rhododendron and Acalabrutinib have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Acalabrutinib interact with any supplements?
Yes. Acalabrutinib has documented interactions with 144 supplements in our database — Rusty-leaved Rhododendron is not one of them. The Acalabrutinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Acalabrutinib and Rusty-leaved Rhododendron?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.