Drug & supplement interaction

S-23 + Mitomycin

Mitomycin brand names: Mutamycin, Mitosol, Jelmyto.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between S-23 and Mitomycin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

S-23 and Mitomycin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mitomycin and S-23 in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for S-23 at all — not against Mitomycin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

S-23 safety at a glance

S-23 overall Avoid S-23 is an unapproved experimental drug with no human safety data and known hormonal risks.
Pregnancy Possibly Unsafe When used orally or parenterally. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing selective androge... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing selective androge... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mitomycin and S-23? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Mitomycin’s Own FDA Label Lists

This is not an interaction — none of it involves S-23. These are the most notable effects listed in the ADVERSE REACTIONS section of Mitomycin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A stroke or mini-stroke Worth acting on
  • Pain or burning when passing urine Worth acting on
  • High potassium Worth acting on
  • A low platelet count Worth acting on
  • Kidney problems Worth acting on
  • Anemia Worth acting on
  • Raised blood pressure Worth acting on
  • A low white blood cell count Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on

Showing the 10 most notable of 23 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Mitomycin. Read the label on DailyMed › S-23’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no S-23 side to compare — that is a limit of the record, not a statement that S-23 has no side effects.

Special populations

S-23 in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing selective androgen receptor modulators (SARMs) are dangerous. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Mitomycin

This page covers S-23 only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mitomycin page lists 26 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Acerola (moderate), Alpha-lipoic Acid (moderate), Coffee Charcoal (moderate) and Dimethylsulfoxide (dmso) (moderate).

By severity: 1 major · 15 moderate · 10 minor.

From our pharmacist’s overview on the Mitomycin page

“Activated charcoal is the entry to know first with mitomycin (Mutamycin, Mitosol, Jelmyto), a chemotherapy drug, because charcoal binds medications and can cut the amount the body receives, and it carries this list's only major rating. A weakened dose of a cancer treatment is a real loss, so I would treat these 26 interactions with gen…”

Reviewed by 2 · Jul 18, 2026

Open the Mitomycin interaction page

One more smart check

Taking S-23 as Part of a Dietary Supplement Product? Check It for Interactions

We hold 5 real supplement products containing S-23, each one broken down to its full ingredient list — and combination products often carry several ingredients besides S-23. Even though S-23 itself has no known interaction with Mitomycin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where S-23 and Mitomycin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement S-23
Steady interest

#1,040 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mitomycin
Top 25%

#385 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every S-23 reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The S-23 and Mitomycin records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About S-23

What is S-23?

  • Muscle building
  • Fat loss
  • Athletic performance enhancement
  • Body recomposition
  • Investigational male contraceptive (research only)

S-23 is an experimental, non-prescription synthetic drug called a selective androgen receptor modulator (SARM), not a dietary supplement, herb, or natural product. It has never been approved for human use, has not been proven safe in people, and is banned in sports; we do not recommend using it.

Not applicable; S-23 is a synthetic chemical compound · Liquid solutions, capsules, and powders sold as 'research chemicals'

An interaction check asks whether these two react with each other — it does not ask whether S-23 is a good idea for someone in your situation. Here is what our S-23 record says about it on its own.

S-23: dosing

There is no established or safe dose of S-23 for humans. It has never gone through the clinical testing that would set a safe and effective dose, so any amounts shared online are unverified and potentially dangerous.We do not provide dosing guidance for S-23 because doing so could imply it is safe to use, which it is not.

From our S-23 monograph — the full record covers uses, side effects and every documented interaction.

Read the full S-23 monograph & all interactions
Medication

About Mitomycin

What Is Mitomycin Used For?

Brand names: Mutamycin, Mitosol, Jelmyto

Mitomycin (and its brand Mutamycin) is used intravenously in combination with other chemotherapy drugs to treat disseminated adenocarcinoma (a type of cancer that has spread) of the stomach or pancreas, when other treatments have not worked. It is not intended to replace surgery or radiation therapy.

Mitomycin is also the active ingredient in other products for different uses: Jelmyto treats low-grade upper tract urothelial cancer (cancer of the upper urinary tract); Zusduri treats recurrent low-grade intermediate-risk non-muscle invasive bladder cancer; and Mitosol is used as a surgical aid during certain glaucoma eye surgery. These are separate products with distinct indications and are not interchangeable with the intravenous injection form.

See full Mitomycin drug information
Keep checking

Other Drugs & S-23

Browse every other medication we’ve checked against S-23 — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked S-23 against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full S-23 list.

See the full S-23 interactions page
See every supplement checked against Mitomycin, ranked by severity
Evidence & sources

S-23 References

The 1 references that drive our S-23 monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking S-23 and Mitomycin Together: Common Questions

Is it safe to take S-23 with Mitomycin?
We do not list a known interaction between S-23 and Mitomycin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Mitomycin interact with any supplements?
Yes. Mitomycin has documented interactions with 26 supplements in our database — S-23 is not one of them. The Mitomycin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

S-23 monograph Uses, safety profile, and every drug interaction in one place Mitomycin drug information The full plain-English guide to this medication Mitomycin supplement interactions Every supplement checked against Mitomycin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Mitomycin and S-23?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.