Drug & supplement interaction

Salatrim + Ixazomib Citrate

Ixazomib Citrate brand name: Ninlaro.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Salatrim and Ixazomib Citrate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Ixazomib Citrate states a food rule worth keeping to.

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Interaction report

Salatrim and Ixazomib Citrate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ixazomib Citrate and Salatrim in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Salatrim at all — not against Ixazomib Citrate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Salatrim safety at a glance

Salatrim overall Use caution Generally used in foods in limited amounts, but larger intakes can cause digestive upset.
Pregnancy Use caution There is little specific safety data in pregnancy, so it is best to be cautious.
Breastfeeding Use caution There is little specific safety data while breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ixazomib Citrate and Salatrim? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Ixazomib Citrate’s Own FDA Label Lists

This is not an interaction — none of it involves Salatrim. These are the most notable effects listed in the ADVERSE REACTIONS section of Ixazomib Citrate’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 3 of them are worth acting on rather than waiting out — marked below.

  • A low platelet count Worth acting on
  • A low white blood cell count Worth acting on
  • Liver problems Worth acting on
  • Numbness or tingling
  • Constipation
  • Swelling
  • Diarrhea
  • A skin rash
  • Vomiting
  • Nausea

From the ADVERSE REACTIONS section of the FDA label for Ixazomib Citrate. Read the label on DailyMed › Salatrim’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Salatrim side to compare — that is a limit of the record, not a statement that Salatrim has no side effects.

How to take them

Some Ixazomib Citrate Products Have a Food Rule — Salatrim Should Not Break It

At least one FDA label for a product containing Ixazomib Citrate says to take it on an empty stomach. Most supplements — Salatrim included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Ixazomib Citrate on its own and move Salatrim to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Ixazomib Citrate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

( 2.1 ) Dose should be taken at least one hour before or at least two hours after food.

From the Dosage and Administration section of the FDA label we read for Ixazomib Citrate — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Ixazomib Citrate

This page covers Salatrim only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ixazomib Citrate page lists 168 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 124 moderate · 38 minor.

From our pharmacist’s overview on the Ixazomib Citrate page

“Anyone taking ixazomib citrate (Ninlaro) for multiple myeloma should give this list real weight, because a supplement that shifts this chemotherapy's blood level can shift how well it works against the cancer. Of the 168 ingredients on file, 121 act on CYP3A4, the enzyme that clears ixazomib.”

Reviewed by 2 · Jul 18, 2026

Open the Ixazomib Citrate interaction page

How much people look this up

Where Salatrim and Ixazomib Citrate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Salatrim
Steady interest

#775 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ixazomib Citrate
Top half

#1,026 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Salatrim is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Salatrim reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Salatrim and Ixazomib Citrate records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Salatrim

What is Salatrim?

  • Reduced-calorie fat replacement in foods
  • Lower-calorie baked goods and confections
  • Reducing dietary fat calories
  • Food texture and mouthfeel similar to regular fat

Salatrim is a man-made, reduced-calorie fat used as an ingredient in processed foods, not a traditional herb or supplement you would take on its own. It is designed to provide fewer calories than ordinary fat, but eating large amounts may cause stomach and bowel discomfort. If you have questions about products containing it, check the food label and ask your pharmacist or doctor.

Not applicable (manufactured fat ingredient) · Reduced-fat or reduced-calorie processed foods such as baked goods, chocolate, confections, and dairy-type products

An interaction check asks whether these two react with each other — it does not ask whether Salatrim is a good idea for someone in your situation. Here is what our Salatrim record says about it on its own.

Salatrim: dosing

There is no established supplement dose for Salatrim, because it is a food ingredient rather than a pill or capsule you would take by itself. The amount you get depends on the food product and how much of it you eat.If you choose foods made with Salatrim, follow the serving sizes listed on the food label and avoid eating very large amounts at once to lower the chance of digestive upset.

From our Salatrim monograph — the full record covers uses, side effects and every documented interaction.

Read the full Salatrim monograph & all interactions
Medication

About Ixazomib

What Is Ixazomib Used For?

Brand name: Ninlaro

Ninlaro (ixazomib) is used to treat multiple myeloma — a cancer of plasma cells in the bone marrow. It is always used together with two other medicines, lenalidomide and dexamethasone, and is approved for adults who have already tried at least one other treatment.

Ninlaro is not recommended as maintenance therapy or for newly diagnosed multiple myeloma in combination with lenalidomide and dexamethasone outside of controlled clinical trials.

See full Ixazomib drug information
Keep checking

Other Drugs & Salatrim

Browse every other medication we’ve checked against Salatrim — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Salatrim References

The 2 sources that drive our Salatrim monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Salatrim is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Food Additives & Ingredients — U.S. Food and Drug Administration Source
  2. Fat Replacers — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Salatrim and Ixazomib Citrate Together: Common Questions

Is it safe to take Salatrim with Ixazomib Citrate?
We do not list a known interaction between Salatrim and Ixazomib Citrate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Salatrim and Ixazomib Citrate at the same time of day?
At least one FDA label for a product containing Ixazomib Citrate says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Ixazomib Citrate on its own and move Salatrim to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Ixazomib Citrate interact with any supplements?
Yes. Ixazomib Citrate has documented interactions with 168 supplements in our database — Salatrim is not one of them. The Ixazomib Citrate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Ixazomib Citrate and Salatrim?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.