Ixazomib

Generic name: Pronounced as (ix az' oh mib)
Brand names
  • Ninlaro®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 02/15/2016

Ixazomib is used in combination with lenalidomide (Revlimid) and dexamethasone to treat multiple myeloma (cancer of the plasma cells in the bone marrow) that has worsened after treatment with other chemotherapy medications. Ixazomib is in a class of medications called proteasome inhibitors. It works by helping to kill cancer cells.

Ixazomib comes as a capsule to take by mouth. It is usually taken with water on an empty stomach, at least 1 hour before or 2 hours after eating. It is taken on days 1,8, and 15 of a 28 day treatment cycle. Take ixazomib at around the same time on every day that you take it. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ixazomib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Do not take ixazomib and dexamethasone at the same time because you should take dexamethasone with food.

Swallow the capsules whole; do not split, chew, or crush them.

Be careful when handling ixazomib capsules. Do not allow your skin, eyes, mouth, or nose to come into contact with broken or crushed ixazomib capsules. If such contact occurs, wash your skin well with soap and water or rinse your eyes well with plain water.

If you vomit after taking ixazomib, do not repeat the dose. Take your next dose of ixazomib on the next scheduled day that you are supposed to take it.

Your doctor may need to temporarily or permanently stop your treatment or decrease your dose of ixazomib, or of the other medications that you are taking, depending on the side effects that you experience. Be sure to talk to your doctor about how you are feeling during your treatment. Do not stop taking ixazomib without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking ixazomib,

  • tell your doctor and pharmacist if you are allergic to ixazomib, any other medications, or any of the ingredients in ixazomib capsules. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements you are taking or plan to take. Be sure to mention any of the following: carbamazepine (Epitol, Equetro, Carbatrol, Tegretol, Teril), efavirenz (Sustiva, in Atripla), nevirapine (Viramune), phenobarbital, pioglitazone (Actos, in Actoplus, Duetact, Oseni), phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), and rifampin (Rifadin, Rimactane, in Rifamate, Rifater). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor what herbal products you are taking, especially St. John's wort.

  • tell your doctor if you have or have ever had liver or kidney disease.

  • tell your doctor if you are pregnant or plan to become pregnant, or plan to father a child. You should not become pregnant while you are taking ixazomib. Use effective birth control during your treatment with ixazomib and for 90 days after your final dose. If you are a male and your partner can become pregnant, you should use effective birth control during your treatment and for 90 days after your final dose. Talk to your doctor about birth control methods that will work for you. If you or your partner become pregnant while taking ixazomib, call your doctor immediately. Ixazomib can harm the fetus.

  • tell your doctor if you are breastfeeding. You should not breastfeed while you are taking ixazomib.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is within 72 hours (3 days) of your next scheduled dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Ixazomib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • diarrhea

    • constipation

    • nausea

    • new or worsening rash

    • back pain

    • unusual swelling of your arms or legs

    • weight gain due to swelling

    • blurred vision

    • dry eyes

    • pink eye

  • Some side effects can be serious. If you experience any of these symptoms call your doctor immediately:

    • nausea

    • extreme tiredness

    • loss of appetite

    • flu-like symptoms

    • unusual bleeding or bruising

    • yellowing of your skin or eyes

    • pain in the upper right part of your stomach

    • burning, tingling, numbness, pain, or weakness in arms or legs

    • bloody or black, tarry stool

  • Ixazomib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Leave the medication in the original packaging until right before you take it.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to ixazomib.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Delavirdine Delavirdine The metabolism of Ixazomib can be decreased when combined with Delavirdine.
Cilostazol Cilostazol Cilostazol may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Ixazomib can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Conjugated estrogens may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Fenofibrate Fenofibrate The metabolism of Ixazomib can be decreased when combined with Fenofibrate.
Guanfacine Guanfacine Guanfacine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Magnesium Hydroxide Magnesium Hydroxide Magnesium hydroxide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Methylergonovine Methylergonovine The metabolism of Ixazomib can be decreased when combined with Methylergometrine.
Mycophenolate Mycophenolate Mycophenolic acid may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Olsalazine Olsalazine Olsalazine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Potassium Potassium Potassium cation may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Prednisone Prednisone Prednisone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ranitidine Ranitidine Ranitidine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Reserpine Reserpine Reserpine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Rizatriptan Rizatriptan Rizatriptan may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Sumatriptan Sumatriptan Sumatriptan may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Tacrolimus Tacrolimus The metabolism of Ixazomib can be decreased when combined with Tacrolimus.
Triamcinolone Triamcinolone The metabolism of Ixazomib can be increased when combined with Triamcinolone.
Ampicillin Injection Ampicillin Injection Ampicillin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Doxycycline Injection Doxycycline Injection The metabolism of Ixazomib can be decreased when combined with Doxycycline.
Fluconazole Injection Fluconazole Injection The metabolism of Ixazomib can be decreased when combined with Fluconazole.
Foscarnet Injection Foscarnet Injection Foscarnet may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Hydromorphone Injection Hydromorphone Injection Hydromorphone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Levofloxacin Injection Levofloxacin Injection Levofloxacin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Meperidine Injection Meperidine Injection The metabolism of Ixazomib can be increased when combined with Meperidine.
Methylprednisolone Injection Methylprednisolone Injection The metabolism of Ixazomib can be increased when combined with Methylprednisolone.
Metoclopramide Injection Metoclopramide Injection Metoclopramide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Metronidazole Injection Metronidazole Injection The metabolism of Ixazomib can be decreased when combined with Metronidazole.
Pamidronate Injection Pamidronate Injection Pamidronic acid may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Vancomycin Injection Vancomycin Injection Ixazomib may decrease the excretion rate of Vancomycin which could result in a higher serum level.
Altretamine Altretamine Amphetamine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cefuroxime Cefuroxime Cefuroxime may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cyclosporine Cyclosporine The metabolism of Ixazomib can be decreased when combined with Cyclosporine.
Torsemide Torsemide Torasemide may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Meloxicam Meloxicam Meloxicam may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Orlistat Orlistat The metabolism of Ixazomib can be increased when combined with Orlistat.
Oxcarbazepine Oxcarbazepine The metabolism of Ixazomib can be increased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Temozolomide Temozolomide Temozolomide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Zaleplon Zaleplon Zaleplon may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Anakinra Anakinra The metabolism of Ixazomib can be increased when combined with Anakinra.
Etanercept Injection Etanercept Injection The metabolism of Ixazomib can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Ixazomib can be increased when combined with Modafinil.
Perindopril Perindopril Perindopril may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Tenofovir Tenofovir The metabolism of Ixazomib can be decreased when combined with Tenofovir.
Choline Magnesium Trisalicylate Choline Magnesium Trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Epinephrine Injection Epinephrine Injection The metabolism of Ixazomib can be decreased when combined with Epinephrine.
Eplerenone Eplerenone Eplerenone may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Zonisamide Zonisamide Zonisamide may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Adalimumab Injection Adalimumab Injection The metabolism of Ixazomib can be increased when combined with Adalimumab.
Atomoxetine Atomoxetine Atomoxetine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Atazanavir Atazanavir The metabolism of Ixazomib can be decreased when combined with Atazanavir.
Almotriptan Almotriptan Almotriptan may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Mefloquine Mefloquine The metabolism of Ixazomib can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Ixazomib can be decreased when combined with Rosuvastatin.
Aprepitant Aprepitant The metabolism of Ixazomib can be decreased when combined with Aprepitant.
Emtricitabine Emtricitabine Emtricitabine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Memantine Memantine Memantine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Tadalafil Tadalafil Tadalafil may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Progesterone Progesterone The metabolism of Ixazomib can be increased when combined with Progesterone.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Ixazomib.
Infliximab Injection Infliximab Injection The metabolism of Ixazomib can be increased when combined with Infliximab.
Rifaximin Rifaximin The metabolism of Ixazomib can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Ixazomib can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Ixazomib can be decreased when combined with Norethisterone.
Tinidazole Tinidazole Tinidazole may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Bosentan Bosentan The metabolism of Ixazomib can be increased when combined with Bosentan.
Cefditoren Cefditoren Cefdinir may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cyanocobalamin Injection Cyanocobalamin Injection Hydroxocobalamin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Erlotinib Erlotinib The metabolism of Ixazomib can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone Eszopiclone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ganciclovir Ganciclovir Ganciclovir may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ribavirin Ribavirin Ribavirin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Valganciclovir Valganciclovir Valganciclovir may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Voriconazole Voriconazole The metabolism of Ixazomib can be decreased when combined with Voriconazole.
Adefovir Adefovir Adefovir may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Dextroamphetamine Dextroamphetamine Amphetamine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ramelteon Ramelteon Ramelteon may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Fentanyl Fentanyl Fentanyl may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Pregabalin Pregabalin Pregabalin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Deferasirox Deferasirox The metabolism of Ixazomib can be increased when combined with Deferasirox.
Tipranavir Tipranavir The metabolism of Ixazomib can be decreased when combined with Tipranavir.
Felbamate Felbamate The metabolism of Ixazomib can be increased when combined with Felbamate.
Ranolazine Ranolazine The metabolism of Ixazomib can be decreased when combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Ixazomib can be increased when combined with Abatacept.
Rasagiline Rasagiline Rasagiline may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Imatinib Imatinib The metabolism of Ixazomib can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin Sitagliptin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Varenicline Varenicline Varenicline may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Gefitinib Gefitinib The metabolism of Ixazomib can be decreased when combined with Gefitinib.
Albuterol Albuterol Salbutamol may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Paliperidone Paliperidone Paliperidone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Clofarabine Injection Clofarabine Injection Clofarabine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lubiprostone Lubiprostone Lubiprostone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Posaconazole Posaconazole The metabolism of Ixazomib can be decreased when combined with Posaconazole.
Primaquine Primaquine The metabolism of Ixazomib can be decreased when combined with Primaquine.
Darunavir Darunavir The serum concentration of Ixazomib can be increased when it is combined with Darunavir.
Pemetrexed Injection Pemetrexed Injection Ixazomib may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
Sorafenib Sorafenib The metabolism of Ixazomib can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Ixazomib can be decreased when combined with Sunitinib.
Lapatinib Lapatinib The metabolism of Ixazomib can be decreased when combined with Lapatinib.
Levocetirizine Levocetirizine Levocetirizine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Pegaptanib Injection Pegaptanib Injection Pegaptanib may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Dasatinib Dasatinib The metabolism of Ixazomib can be decreased when combined with Dasatinib.
Armodafinil Armodafinil The metabolism of Ixazomib can be increased when combined with Armodafinil.
Azacitidine Injection Azacitidine Injection Azacitidine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ivermectin Ivermectin The metabolism of Ixazomib can be increased when combined with Ivermectin.
Lenalidomide Lenalidomide Lenalidomide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Nilotinib Nilotinib The metabolism of Ixazomib can be decreased when combined with Nilotinib.
Bexarotene Bexarotene The metabolism of Ixazomib can be increased when combined with Bexarotene.
Budesonide Budesonide The metabolism of Ixazomib can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Ixazomib can be decreased when combined with Chloramphenicol.
Desmopressin Desmopressin Desmopressin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Doripenem Injection Doripenem Injection Doripenem may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Etravirine Etravirine The metabolism of Ixazomib can be increased when combined with Etravirine.
Arsenic Trioxide Injection Arsenic Trioxide Injection Arsenic trioxide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Mitoxantrone Injection Mitoxantrone Injection The metabolism of Ixazomib can be decreased when combined with Mitoxantrone.
Desvenlafaxine Desvenlafaxine The metabolism of Ixazomib can be decreased when combined with Desvenlafaxine.
Cevimeline Cevimeline Cevimeline may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Pilocarpine Pilocarpine The metabolism of Ixazomib can be decreased when combined with Pilocarpine.
Certolizumab Injection Certolizumab Injection The metabolism of Ixazomib can be increased when combined with Certolizumab pegol.
Daptomycin Injection Daptomycin Injection Daptomycin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Mitotane Mitotane The metabolism of Ixazomib can be increased when combined with Mitotane.
Methylnaltrexone Injection Methylnaltrexone Injection Methylnaltrexone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Rufinamide Rufinamide The metabolism of Ixazomib can be increased when combined with Rufinamide.
Midazolam Midazolam The metabolism of Ixazomib can be decreased when combined with Midazolam.
Dexrazoxane Injection Dexrazoxane Injection Dexrazoxane may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Milnacipran Milnacipran The metabolism of Ixazomib can be decreased when combined with Milnacipran.
Plerixafor Injection Plerixafor Injection Plerixafor may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Fesoterodine Fesoterodine Fesoterodine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Prasugrel Prasugrel Prasugrel may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lacosamide Lacosamide The metabolism of Ixazomib can be decreased when combined with Lacosamide.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) Tolvaptan may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Dronedarone Dronedarone The serum concentration of Ixazomib can be increased when it is combined with Dronedarone.
Pralatrexate Injection Pralatrexate Injection Pralatrexate may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection Palonosetron may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Saxagliptin Saxagliptin Saxagliptin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Telavancin Injection Telavancin Injection Telavancin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Topotecan Topotecan The metabolism of Ixazomib can be increased when combined with Topotecan.
Golimumab Injection Golimumab Injection The metabolism of Ixazomib can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Ixazomib can be decreased when combined with Pazopanib.
Albendazole Albendazole The metabolism of Ixazomib can be decreased when combined with Albendazole.
Tocilizumab Injection Tocilizumab Injection The metabolism of Ixazomib can be increased when combined with Tocilizumab.
Dalfampridine Dalfampridine Dalfampridine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ceftaroline Injection Ceftaroline Injection Ceftaroline fosamil may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Acetaminophen Injection Acetaminophen Injection The metabolism of Ixazomib can be increased when combined with Acetaminophen.
Ipilimumab Injection Ipilimumab Injection Ipilimumab may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Denileukin Diftitox Injection Denileukin Diftitox Injection The metabolism of Ixazomib can be decreased when combined with Aldesleukin.
Terbutaline Injection Terbutaline Injection Terbutaline may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Roflumilast Roflumilast The metabolism of Ixazomib can be decreased when combined with Roflumilast.
Linagliptin Linagliptin The metabolism of Ixazomib can be decreased when combined with Linagliptin.
Rilpivirine Rilpivirine The metabolism of Ixazomib can be decreased when combined with Rilpivirine.
Telaprevir Telaprevir The metabolism of Ixazomib can be decreased when combined with Glecaprevir.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Ixazomib can be increased when combined with Cyclophosphamide.
Rivaroxaban Rivaroxaban Rivaroxaban may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ticagrelor Ticagrelor The metabolism of Ixazomib can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Ixazomib can be decreased when combined with Brentuximab vedotin.
Ruxolitinib Ruxolitinib Ruxolitinib may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Clobazam Clobazam The metabolism of Ixazomib can be increased when combined with Clobazam.
Vemurafenib Vemurafenib The metabolism of Ixazomib can be increased when combined with Vemurafenib.
Ivacaftor Ivacaftor The metabolism of Ixazomib can be decreased when combined with Ivacaftor.
Deferiprone Deferiprone Deferiprone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Crizotinib Crizotinib The metabolism of Ixazomib can be decreased when combined with Crizotinib.
Cabergoline Cabergoline The metabolism of Ixazomib can be decreased when combined with Cabergoline.
Naloxone Injection Naloxone Injection The metabolism of Ixazomib can be decreased when combined with Naloxone.
Fondaparinux Injection Fondaparinux Injection Fondaparinux may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Enzalutamide Enzalutamide The metabolism of Ixazomib can be increased when combined with Enzalutamide.
Mirabegron Mirabegron Mirabegron may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Regorafenib Regorafenib The metabolism of Ixazomib can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The metabolism of Ixazomib can be decreased when combined with Bosutinib.
Corticotropin, Repository Injection Corticotropin, Repository Injection The metabolism of Ixazomib can be increased when combined with Corticotropin.
Teduglutide Injection Teduglutide Injection Teduglutide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Alogliptin Alogliptin Alogliptin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Pomalidomide Pomalidomide Pomalidomide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Ixazomib can be decreased when combined with Trastuzumab emtansine.
Canagliflozin Canagliflozin Canagliflozin may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Methazolamide Methazolamide Methazolamide may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Dabrafenib Dabrafenib The metabolism of Ixazomib can be increased when combined with Dabrafenib.
Trametinib Trametinib The metabolism of Ixazomib can be increased when combined with Trametinib.
Levomilnacipran Levomilnacipran Levomilnacipran may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ertapenem Injection Ertapenem Injection Ertapenem may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Vortioxetine Vortioxetine Vortioxetine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Perampanel Perampanel The metabolism of Ixazomib can be increased when combined with Perampanel.
Lomitapide Lomitapide The metabolism of Ixazomib can be decreased when combined with Lomitapide.
Ketorolac Injection Ketorolac Injection Ketorolac may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Simeprevir Simeprevir The metabolism of Ixazomib can be decreased when combined with Simeprevir.
Sofosbuvir Sofosbuvir Sofosbuvir may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Dapagliflozin Dapagliflozin Dapagliflozin may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Apremilast Apremilast The metabolism of Ixazomib can be increased when combined with Apremilast.
Droxidopa Droxidopa Droxidopa may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ceritinib Ceritinib The metabolism of Ixazomib can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Ixazomib can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The metabolism of Ixazomib can be increased when combined with Eslicarbazepine.
Idelalisib Idelalisib The metabolism of Ixazomib can be decreased when combined with Idelalisib.
Testosterone Injection Testosterone Injection The metabolism of Ixazomib can be increased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Ixazomib can be increased when combined with Oritavancin.
Vorapaxar Vorapaxar The metabolism of Ixazomib can be decreased when combined with Vorapaxar.
Suvorexant Suvorexant The metabolism of Ixazomib can be decreased when combined with Suvorexant.
Edoxaban Edoxaban Edoxaban may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Olaparib Olaparib The metabolism of Ixazomib can be decreased when combined with Olaparib.
Methamphetamine Methamphetamine Metamfetamine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Tasimelteon Tasimelteon The metabolism of Ixazomib can be decreased when combined with Tasimelteon.
Lanreotide Injection Lanreotide Injection The metabolism of Ixazomib can be decreased when combined with Lanreotide.
Nintedanib Nintedanib The metabolism of Ixazomib can be decreased when combined with Nintedanib.
Secukinumab Injection Secukinumab Injection The metabolism of Ixazomib can be increased when combined with Secukinumab.
Palbociclib Palbociclib The metabolism of Ixazomib can be decreased when combined with Palbociclib.
Lenvatinib Lenvatinib The metabolism of Ixazomib can be increased when combined with Lenvatinib.
Haloperidol Injection Haloperidol Injection The serum concentration of Ixazomib can be increased when it is combined with Haloperidol.
Amiloride Amiloride Amiloride may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Isavuconazonium Injection Isavuconazonium Injection The metabolism of Ixazomib can be increased when combined with Isavuconazonium.
Macitentan Macitentan Macitentan may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Prednisolone Prednisolone The metabolism of Ixazomib can be increased when combined with Prednisolone.
Ziprasidone Injection Ziprasidone Injection The metabolism of Ixazomib can be decreased when combined with Ziprasidone.
Penicillin G Procaine Injection Penicillin G Procaine Injection Procaine benzylpenicillin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cobimetinib Cobimetinib The metabolism of Ixazomib can be decreased when combined with Cobimetinib.
Osimertinib Osimertinib The metabolism of Ixazomib can be increased when combined with Osimertinib.
Rifapentine Rifapentine The metabolism of Ixazomib can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Lesinurad can be increased when combined with Ixazomib.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The metabolism of Ixazomib can be decreased when combined with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The metabolism of Ixazomib can be increased when combined with Dexamethasone.
Brivaracetam Injection Brivaracetam Injection Brivaracetam may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Venetoclax Venetoclax The metabolism of Ixazomib can be decreased when combined with Venetoclax.
Cobicistat Cobicistat The metabolism of Ixazomib can be decreased when combined with Cobicistat.
Furosemide Injection Furosemide Injection Furosemide may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Rucaparib Rucaparib The metabolism of Ixazomib can be decreased when combined with Rucaparib.
Lixisenatide Injection Lixisenatide Injection Lixisenatide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ribociclib Ribociclib The metabolism of Ixazomib can be decreased when combined with Ribociclib.
Brigatinib Brigatinib The metabolism of Ixazomib can be increased when combined with Brigatinib.
Doxepin (Insomnia) Doxepin (Insomnia) Doxepin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Deutetrabenazine Deutetrabenazine Ixazomib may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
Valbenazine Valbenazine Ixazomib may decrease the excretion rate of Valbenazine which could result in a higher serum level.
Deflazacort Deflazacort The metabolism of Ixazomib can be increased when combined with Deflazacort.
Naldemedine Naldemedine Ixazomib may decrease the excretion rate of Naldemedine which could result in a higher serum level.
Sarilumab Injection Sarilumab Injection The metabolism of Ixazomib can be increased when combined with Sarilumab.
Midostaurin Midostaurin The metabolism of Ixazomib can be increased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Ixazomib can be increased when combined with Enasidenib.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Ixazomib can be increased when combined with Fosaprepitant.
Benznidazole Benznidazole Ixazomib may decrease the excretion rate of Benznidazole which could result in a higher serum level.
Delafloxacin Delafloxacin Ixazomib may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Acalabrutinib Acalabrutinib The metabolism of Ixazomib can be decreased when combined with Acalabrutinib.
Letermovir Letermovir The metabolism of Ixazomib can be decreased when combined with Letermovir.
Ertugliflozin Ertugliflozin Ertugliflozin may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Buprenorphine Injection Buprenorphine Injection The metabolism of Ixazomib can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide The metabolism of Apalutamide can be increased when combined with Ixazomib.
Fostamatinib Fostamatinib The metabolism of Ixazomib can be decreased when combined with Fostamatinib.
Baricitinib Baricitinib Ixazomib may decrease the excretion rate of Baricitinib which could result in a higher serum level.
Lofexidine Lofexidine Lofexidine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Plazomicin Injection Plazomicin Injection Ixazomib may decrease the excretion rate of Plazomicin which could result in a higher serum level.
Ivosidenib Ivosidenib The metabolism of Ixazomib can be increased when combined with Ivosidenib.
Dacomitinib Dacomitinib The metabolism of Ixazomib can be decreased when combined with Dacomitinib.
Duvelisib Duvelisib The metabolism of Ixazomib can be decreased when combined with Duvelisib.
Stiripentol Stiripentol The metabolism of Ixazomib can be decreased when combined with Stiripentol.
Gilteritinib Gilteritinib The metabolism of Ixazomib can be decreased when combined with Gilteritinib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Ixazomib.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Ixazomib can be increased when combined with Paclitaxel.
Rifamycin Rifamycin The metabolism of Ixazomib can be increased when combined with Rifamycin.
Prucalopride Prucalopride The metabolism of Ixazomib can be decreased when combined with Prucalopride.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Ixazomib can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Ixazomib can be decreased when combined with Siponimod.
Acyclovir Ophthalmic Acyclovir Ophthalmic Acyclovir may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Alpelisib Alpelisib The metabolism of Ixazomib can be increased when combined with Alpelisib.
Solriamfetol Solriamfetol Ixazomib may decrease the excretion rate of Solriamfetol which could result in a higher serum level.
Triclabendazole Triclabendazole The metabolism of Ixazomib can be decreased when combined with Triclabendazole.
Pitolisant Pitolisant The serum concentration of Ixazomib can be decreased when it is combined with Pitolisant.
Lefamulin Lefamulin The serum concentration of Ixazomib can be increased when it is combined with Lefamulin.
Phenytoin Injection Phenytoin Injection The metabolism of Ixazomib can be increased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Ixazomib can be increased when combined with Fosphenytoin.
Voxelotor Voxelotor The serum concentration of Ixazomib can be increased when it is combined with Voxelotor.
Tazemetostat Tazemetostat The metabolism of Ixazomib can be decreased when combined with Tazemetostat.
Cenobamate Cenobamate The serum concentration of Ixazomib can be decreased when it is combined with Cenobamate.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Ixazomib.
Octreotide Octreotide The serum concentration of Ixazomib can be increased when it is combined with Octreotide.
Pralsetinib Pralsetinib The metabolism of Ixazomib can be increased when combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Ixazomib can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Ixazomib can be decreased when combined with Drospirenone.
Viloxazine Viloxazine Viloxazine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) The metabolism of Ixazomib can be increased when combined with Vitamin E.
Tobramycin Injection Tobramycin Injection Tobramycin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Fenoprofen Fenoprofen Fenoprofen may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Indomethacin Indomethacin Indomethacin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Mefenamic Acid Mefenamic Acid Mefenamic acid may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Naproxen Naproxen Naproxen may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Tolmetin Tolmetin Tolmetin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Sulindac Sulindac Sulindac may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Isotretinoin Isotretinoin Isotretinoin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Sucralfate Sucralfate Sucralfate may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Floxuridine Floxuridine Floxuridine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Phenobarbital Phenobarbital The metabolism of Ixazomib can be increased when combined with Phenobarbital.
Metaxalone Metaxalone Metaxalone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Methotrexate Injection Methotrexate Injection Methotrexate may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Primidone Primidone The metabolism of Ixazomib can be increased when combined with Primidone.
Chlorpromazine Chlorpromazine The metabolism of Ixazomib can be increased when combined with Chlorpromazine.
Diazepam Diazepam The metabolism of Ixazomib can be decreased when combined with Diazepam.
Oxazepam Oxazepam Oxazepam may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Flurazepam Flurazepam Flurazepam may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Clorazepate Clorazepate Clorazepic acid may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lorazepam Lorazepam The metabolism of Ixazomib can be decreased when combined with Lorazepam.
Carmustine Carmustine Carmustine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Amantadine Amantadine Amantadine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Codeine Codeine Codeine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Bromocriptine Bromocriptine The metabolism of Ixazomib can be decreased when combined with Bromocriptine.
Tranylcypromine Tranylcypromine The metabolism of Ixazomib can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Ixazomib can be decreased when combined with Phenelzine.
Tetracycline Tetracycline The metabolism of Ixazomib can be decreased when combined with Tetracycline.
Prochlorperazine Prochlorperazine The metabolism of Ixazomib can be decreased when combined with Prochlorperazine.
Bleomycin Bleomycin Bleomycin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Sulfadiazine Sulfadiazine Sulfadiazine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Methadone Methadone The metabolism of Ixazomib can be increased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Ixazomib can be decreased when combined with Oxybutynin.
Benztropine Benztropine Benzatropine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Maprotiline Maprotiline Maprotiline may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ibuprofen Ibuprofen Ibuprofen may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Orphenadrine Orphenadrine The metabolism of Ixazomib can be decreased when combined with Orphenadrine.
Azathioprine Azathioprine Azathioprine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Phentermine Phentermine The metabolism of Ixazomib can be decreased when combined with Phentermine.
Methylphenidate Methylphenidate Methylphenidate may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Hydrocortisone Hydrocortisone The metabolism of Ixazomib can be increased when combined with Hydrocortisone.
Doxorubicin Doxorubicin The metabolism of Ixazomib can be decreased when combined with Doxorubicin.
Phenazopyridine Phenazopyridine Phenazopyridine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Carbamazepine Carbamazepine The metabolism of Ixazomib can be increased when combined with Carbamazepine.
Methyldopa Methyldopa Methyldopa may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Hydralazine Hydralazine The metabolism of Ixazomib can be decreased when combined with Hydralazine.
Cimetidine Cimetidine The metabolism of Ixazomib can be decreased when combined with Cimetidine.
Gentamicin Injection Gentamicin Injection Gentamicin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Warfarin Warfarin The metabolism of Ixazomib can be increased when combined with Warfarin.
Clonazepam Clonazepam Clonazepam may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Loperamide Loperamide The metabolism of Ixazomib can be decreased when combined with Loperamide.
Promethazine Promethazine Promethazine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Meclofenamate Meclofenamate Meclofenamic acid may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Daunorubicin Daunorubicin The metabolism of Ixazomib can be decreased when combined with Daunorubicin.
Nitrofurantoin Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Griseofulvin Griseofulvin The metabolism of Ixazomib can be increased when combined with Griseofulvin.
Digoxin Digoxin Ixazomib may decrease the excretion rate of Digoxin which could result in a higher serum level.
Chloroquine Chloroquine Chloroquine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Quinine Quinine The metabolism of Ixazomib can be increased when combined with Quinine.
Calcitriol Calcitriol The metabolism of Ixazomib can be increased when combined with Calcitriol.
Triamterene Triamterene Triamterene may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Sulfinpyrazone Sulfinpyrazone The metabolism of Ixazomib can be increased when combined with Sulfinpyrazone.
Chlorothiazide Chlorothiazide Chlorothiazide may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Chlorthalidone Chlorthalidone Chlorthalidone may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Metolazone Metolazone Metolazone may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Isosorbide Isosorbide Isosorbide may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Secobarbital Secobarbital The metabolism of Ixazomib can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Ixazomib can be decreased when combined with Desipramine.
Amitriptyline Amitriptyline Amitriptyline may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Imipramine Imipramine Imipramine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Probenecid Probenecid The metabolism of Ixazomib can be increased when combined with Probenecid.
Quinidine Quinidine The metabolism of Ixazomib can be decreased when combined with Quinidine.
Procainamide Procainamide Procainamide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Isoniazid Isoniazid The metabolism of Ixazomib can be decreased when combined with Isoniazid.
Pyrazinamide Pyrazinamide Pyrazinamide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Rifampin Rifampin The metabolism of Ixazomib can be increased when combined with Rifampicin.
Disopyramide Disopyramide Disopyramide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Valproic Acid Valproic Acid The metabolism of Ixazomib can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Ixazomib can be increased when combined with Tamoxifen.
Butabarbital Butabarbital Butabarbital may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Liothyronine Liothyronine Liothyronine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Methimazole Methimazole The metabolism of Ixazomib can be decreased when combined with Methimazole.
Chlorpropamide Chlorpropamide Chlorpropamide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Tolbutamide Tolbutamide Tolbutamide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Tolazamide Tolazamide Tolazamide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Niacin Niacin The metabolism of Ixazomib can be decreased when combined with Niacin.
Baclofen Baclofen Baclofen may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ethambutol Ethambutol Ethambutol may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Methyclothiazide Methyclothiazide Methyclothiazide may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Hydrochlorothiazide Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Chlorzoxazone Chlorzoxazone Chlorzoxazone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Pyridoxine Pyridoxine Pyridoxine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Folic Acid Folic Acid Folic acid may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Danazol Danazol The metabolism of Ixazomib can be decreased when combined with Danazol.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) Propranolol may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Spironolactone Spironolactone Spironolactone may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Amphotericin B Injection Amphotericin B Injection The metabolism of Ixazomib can be decreased when combined with Amphotericin B.
Phytonadione Phytonadione Phylloquinone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Amikacin Injection Amikacin Injection Amikacin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Nadolol Nadolol Nadolol may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Allopurinol Allopurinol Allopurinol may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Flavoxate Flavoxate Flavoxate may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Colchicine Colchicine The metabolism of Ixazomib can be increased when combined with Colchicine.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cefadroxil Cefadroxil Cefadroxil may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cefazolin Injection Cefazolin Injection Cefazolin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cephalexin Cephalexin The metabolism of Ixazomib can be decreased when combined with Cephalexin.
Cefoxitin Injection Cefoxitin Injection Cefoxitin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Dacarbazine Dacarbazine Dacarbazine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Acetazolamide Acetazolamide The metabolism of Ixazomib can be decreased when combined with Acetazolamide.
Cefotaxime Injection Cefotaxime Injection Cefotaxime may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Calcitonin Salmon Injection Calcitonin Salmon Injection Salmon calcitonin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ketoconazole Ketoconazole The metabolism of Ixazomib can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel Ixazomib may decrease the excretion rate of Pyrantel which could result in a higher serum level.
Vinblastine Vinblastine The metabolism of Ixazomib can be increased when combined with Vinblastine.
Ethacrynic Acid Ethacrynic Acid Etacrynic acid may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Colistimethate Injection Colistimethate Injection Colistimethate may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Metoprolol Metoprolol The metabolism of Ixazomib can be decreased when combined with Metoprolol.
Aspirin Aspirin Acetylsalicylic acid may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Salsalate Salsalate Salsalate may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Alprazolam Alprazolam Alprazolam may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Temazepam Temazepam Temazepam may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Triazolam Triazolam Triazolam may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Dicyclomine Dicyclomine Dicyclomine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Propantheline Propantheline Propantheline may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Trimethoprim Trimethoprim Trimethoprim may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Diltiazem Diltiazem The metabolism of Ixazomib can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Ixazomib can be increased when combined with Nifedipine.
Timolol Timolol Timolol may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Verapamil Verapamil The metabolism of Ixazomib can be decreased when combined with Verapamil.
Pindolol Pindolol Pindolol may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cisplatin Injection Cisplatin Injection Ixazomib may decrease the excretion rate of Cisplatin which could result in a higher serum level.
Diflunisal Diflunisal Diflunisal may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Piroxicam Piroxicam Piroxicam may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Bumetanide Bumetanide Bumetanide may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Etoposide Etoposide The metabolism of Ixazomib can be increased when combined with Etoposide.
Glyburide Glyburide The metabolism of Ixazomib can be decreased when combined with Glyburide.
Glipizide Glipizide Glipizide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Indapamide Indapamide Indapamide may increase the excretion rate of Ixazomib which could result in a lower serum level and potentially a reduction in efficacy.
Amoxicillin Amoxicillin Amoxicillin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Dicloxacillin Dicloxacillin The metabolism of Ixazomib can be increased when combined with Dicloxacillin.
Nafcillin Injection Nafcillin Injection The metabolism of Ixazomib can be increased when combined with Nafcillin.
Oxacillin Injection Oxacillin Injection Oxacillin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Pentoxifylline Pentoxifylline Pentoxifylline may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection Pentamidine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ceftriaxone Injection Ceftriaxone Injection Ceftriaxone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Labetalol Labetalol Labetalol may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Auranofin Auranofin Auranofin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Leuprolide Injection Leuprolide Injection Leuprolide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Gemfibrozil Gemfibrozil Gemfibrozil may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic Adefovir dipivoxil may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ceftazidime Injection Ceftazidime Injection Ceftazidime may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ketoprofen Ketoprofen Ketoprofen may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cefotetan Injection Cefotetan Injection Cefotetan may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Pimozide Pimozide The metabolism of Ixazomib can be decreased when combined with Pimozide.
Flurbiprofen Flurbiprofen Flurbiprofen may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Amiodarone Amiodarone The metabolism of Ixazomib can be decreased when combined with Amiodarone.
Aztreonam Injection Aztreonam Injection Aztreonam may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Buspirone Buspirone Buspirone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lovastatin Lovastatin The metabolism of Ixazomib can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The metabolism of Ixazomib can be decreased when combined with Ciprofloxacin.
Mesalamine Mesalamine Mesalazine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Diclofenac Diclofenac Diclofenac may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Clozapine Clozapine The metabolism of Ixazomib can be increased when combined with Clozapine.
Estazolam Estazolam Estazolam may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Didanosine Didanosine Didanosine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Pentostatin Injection Pentostatin Injection Pentostatin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Clarithromycin Clarithromycin The metabolism of Ixazomib can be decreased when combined with Clarithromycin.
Etodolac Etodolac Etodolac may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Felodipine Felodipine The metabolism of Ixazomib can be decreased when combined with Felodipine.
Fosinopril Fosinopril Fosinopril may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Nabumetone Nabumetone Nabumetone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Ixazomib.
Teniposide Injection Teniposide Injection The metabolism of Ixazomib can be decreased when combined with Teniposide.
Itraconazole Itraconazole The metabolism of Ixazomib can be decreased when combined with Itraconazole.
Lisinopril Lisinopril Lisinopril may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Oxaprozin Oxaprozin Oxaprozin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Rifabutin Rifabutin The metabolism of Ixazomib can be increased when combined with Rifabutin.
Bisoprolol Bisoprolol Bisoprolol may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Doxazosin Doxazosin The metabolism of Ixazomib can be decreased when combined with Doxazosin.
Isradipine Isradipine The metabolism of Ixazomib can be decreased when combined with Isradipine.
Omeprazole Omeprazole The metabolism of Ixazomib can be increased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Ixazomib can be decreased when combined with Cisapride.
Fluvastatin Fluvastatin The metabolism of Ixazomib can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine Venlafaxine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Famciclovir Famciclovir The metabolism of Ixazomib can be decreased when combined with Famciclovir.
Fluvoxamine Fluvoxamine The metabolism of Ixazomib can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Ixazomib can be decreased when combined with Nefazodone.
Lamotrigine Lamotrigine Lamotrigine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Losartan Losartan The metabolism of Ixazomib can be decreased when combined with Losartan.
Valacyclovir Valacyclovir Valaciclovir may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Tramadol Tramadol Tramadol may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Carboplatin Injection Carboplatin Injection Carboplatin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lansoprazole Lansoprazole The metabolism of Ixazomib can be increased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ixazomib can be increased when combined with Ifosfamide.
Nicardipine Nicardipine The metabolism of Ixazomib can be decreased when combined with Nicardipine.
Bupropion Bupropion Bupropion may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ticlopidine Ticlopidine The metabolism of Ixazomib can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The metabolism of Ixazomib can be decreased when combined with Saquinavir.
Metformin Metformin Metformin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Nisoldipine Nisoldipine Nisoldipine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Lamivudine Lamivudine Lamivudine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Acarbose Acarbose Acarbose may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Gemcitabine Injection Gemcitabine Injection Gemcitabine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Ritonavir Ritonavir The serum concentration of Ixazomib can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Ixazomib can be decreased when combined with Docetaxel.
Cidofovir Injection Cidofovir Injection Cidofovir may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Meropenem Injection Meropenem Injection Meropenem may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Clomipramine Clomipramine Clomipramine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Zafirlukast Zafirlukast The metabolism of Ixazomib can be decreased when combined with Zafirlukast.
Fosfomycin Fosfomycin Fosfomycin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Mirtazapine Mirtazapine The metabolism of Ixazomib can be decreased when combined with Mirtazapine.
Topiramate Topiramate The metabolism of Ixazomib can be increased when combined with Topiramate.
Pramipexole Pramipexole Pramipexole may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Azithromycin Azithromycin The metabolism of Ixazomib can be decreased when combined with Azithromycin.
Nilutamide Nilutamide Nilutamide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Flutamide Flutamide Flutamide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Bicalutamide Bicalutamide The metabolism of Ixazomib can be decreased when combined with Bicalutamide.
Raloxifene Raloxifene The metabolism of Ixazomib can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Ixazomib can be decreased when combined with Irbesartan.
Tamsulosin Tamsulosin Tamsulosin may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Quetiapine Quetiapine Quetiapine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cefepime Injection Cefepime Injection Cefepime may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cefprozil Cefprozil Cefprozil may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cefpodoxime Cefpodoxime Cefpodoxime may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Cetirizine Cetirizine Cetirizine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Paroxetine Paroxetine The metabolism of Ixazomib can be decreased when combined with Paroxetine.
Tolcapone Tolcapone Tolcapone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Citalopram Citalopram The metabolism of Ixazomib can be decreased when combined with Citalopram.
Capecitabine Capecitabine Capecitabine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Efavirenz Efavirenz The metabolism of Ixazomib can be increased when combined with Efavirenz.
Abacavir Abacavir Abacavir may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Celecoxib Celecoxib Celecoxib may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Rosiglitazone Rosiglitazone Rosiglitazone may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Tolterodine Tolterodine Tolterodine may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Oseltamivir Oseltamivir Oseltamivir may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Balsalazide Balsalazide Balsalazide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Nateglinide Nateglinide Nateglinide may decrease the excretion rate of Ixazomib which could result in a higher serum level.
Rabeprazole Rabeprazole The metabolism of Ixazomib can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Ixazomib can be increased when combined with Terbinafine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists

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