Drug & supplement interaction

Salatrim + Lisinopril

Lisinopril brand names: Zestril, Prinivil, Qbrelis.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Salatrim and Lisinopril in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Salatrim and Lisinopril

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lisinopril and Salatrim in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Salatrim at all — not against Lisinopril, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Salatrim safety at a glance

Salatrim overall Use caution Generally used in foods in limited amounts, but larger intakes can cause digestive upset.
Pregnancy Use caution There is little specific safety data in pregnancy, so it is best to be cautious.
Breastfeeding Use caution There is little specific safety data while breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lisinopril and Salatrim? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Lisinopril’s Own FDA Label Lists

This is not an interaction — none of it involves Salatrim. These are the most notable effects listed in the ADVERSE REACTIONS section of Lisinopril’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A stroke or mini-stroke Worth acting on
  • Pain or burning when passing urine Worth acting on
  • Memory problems Worth acting on
  • Dehydration Worth acting on
  • High potassium Worth acting on
  • Low sodium Worth acting on
  • Unsteadiness Worth acting on
  • Low blood sugar Worth acting on
  • A slow heartbeat Worth acting on
  • A heart attack Worth acting on

Showing the 10 most notable of 79 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Lisinopril. Read the label on DailyMed › Where a percentage is shown, it is the share of 313,746 voluntary FDA FAERS reports for Lisinopril that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Salatrim’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Salatrim side to compare — that is a limit of the record, not a statement that Salatrim has no side effects.

From our Q&A

Questions About Salatrim or Lisinopril

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Salatrim or Lisinopril, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Lisinopril

This page covers Salatrim only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lisinopril page lists 167 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Asarabacca (major) and Siberian Cocklebur (major).

By severity: 6 major · 137 moderate · 24 minor.

From our pharmacist’s overview on the Lisinopril page

“Lisinopril is an ACE inhibitor that lowers blood pressure and protects the heart and kidneys, so the 167 supplements and herbs on this page warrant genuine care. Six carry a major rating, and those deserve your attention first.”

Reviewed by 2 · Jul 18, 2026

Open the Lisinopril interaction page

How much people look this up

Where Salatrim and Lisinopril Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Salatrim
Steady interest

#780 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lisinopril
Top 1%

#26 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Salatrim is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Salatrim reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Salatrim and Lisinopril records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Salatrim

What is Salatrim?

  • Reduced-calorie fat replacement in foods
  • Lower-calorie baked goods and confections
  • Reducing dietary fat calories
  • Food texture and mouthfeel similar to regular fat

Salatrim is a man-made, reduced-calorie fat used as an ingredient in processed foods, not a traditional herb or supplement you would take on its own. It is designed to provide fewer calories than ordinary fat, but eating large amounts may cause stomach and bowel discomfort. If you have questions about products containing it, check the food label and ask your pharmacist or doctor.

Not applicable (manufactured fat ingredient) · Reduced-fat or reduced-calorie processed foods such as baked goods, chocolate, confections, and dairy-type products

An interaction check asks whether these two react with each other — it does not ask whether Salatrim is a good idea for someone in your situation. Here is what our Salatrim record says about it on its own.

Salatrim: dosing

There is no established supplement dose for Salatrim, because it is a food ingredient rather than a pill or capsule you would take by itself. The amount you get depends on the food product and how much of it you eat.If you choose foods made with Salatrim, follow the serving sizes listed on the food label and avoid eating very large amounts at once to lower the chance of digestive upset.

From our Salatrim monograph — the full record covers uses, side effects and every documented interaction.

Read the full Salatrim monograph & all interactions
Medication

About Lisinopril

What Is Lisinopril Used For?

Brand names: Zestril, Prinivil, Qbrelis

Lisinopril treats high blood pressure (hypertension) in adults and children 6 years and older, and can be used alone or alongside other blood pressure medicines. Lowering blood pressure reduces the risk of strokes and heart attacks. The tablet combination product containing lisinopril and hydrochlorothiazide is specifically indicated for high blood pressure.

Lisinopril is also used as an add-on therapy to reduce signs and symptoms of systolic heart failure, and to reduce the risk of death in people who are hemodynamically stable (have reasonably stable circulation) within 24 hours of an acute heart attack (acute myocardial infarction).

Most-Reported Side Effects for Lisinopril

From FAERS, the FDA’s public side-effect reporting system (313,746 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 20,515 reports
Nausea 19,130 reports
Diarrhea 17,858 reports
Dyspnea 14,363 reports
Dizziness 13,969 reports
See full Lisinopril drug information
Keep checking

Other Drugs & Salatrim

Browse every other medication we’ve checked against Salatrim — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Salatrim against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Salatrim list.

See the full Salatrim interactions page
See every supplement checked against Lisinopril, ranked by severity
Evidence & sources

Salatrim References

The 2 sources that drive our Salatrim monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Salatrim is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Food Additives & Ingredients — U.S. Food and Drug Administration Source
  2. Fat Replacers — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Salatrim and Lisinopril Together: Common Questions

Is it safe to take Salatrim with Lisinopril?
We do not list a known interaction between Salatrim and Lisinopril. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Lisinopril interact with any supplements?
Yes. Lisinopril has documented interactions with 167 supplements in our database — Salatrim is not one of them. The Lisinopril interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Salatrim monograph Uses, safety profile, and every drug interaction in one place Lisinopril drug information The full plain-English guide to this medication Lisinopril supplement interactions Every supplement checked against Lisinopril, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Lisinopril and Salatrim?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.