Drug & supplement interaction

Salatrim + tipranavir

tipranavir brand name: Aptivus.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Salatrim and tipranavir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for tipranavir states a food rule worth keeping to.

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Interaction report

Salatrim and tipranavir

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between tipranavir and Salatrim in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Salatrim at all — not against tipranavir, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Salatrim safety at a glance

Salatrim overall Use caution Generally used in foods in limited amounts, but larger intakes can cause digestive upset.
Pregnancy Use caution There is little specific safety data in pregnancy, so it is best to be cautious.
Breastfeeding Use caution There is little specific safety data while breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining tipranavir and Salatrim? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What tipranavir’s Own FDA Label Lists

This is not an interaction — none of it involves Salatrim. These are the most notable effects listed in the ADVERSE REACTIONS section of tipranavir’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 5 of them are worth acting on rather than waiting out — marked below.

  • Dehydration Worth acting on
  • Anemia Worth acting on
  • Shortness of breath Worth acting on
  • A low white blood cell count Worth acting on
  • Bleeding or bruising Worth acting on
  • Weight loss
  • Vomiting mentioned in 19.9% of FDA reports for tipranavir
  • Nausea mentioned in 20.5% of FDA reports for tipranavir
  • Numbness or tingling
  • Muscle pain

Showing the 10 most notable of 17 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for tipranavir. Read the label on DailyMed › Where a percentage is shown, it is the share of 1,379 voluntary FDA FAERS reports for tipranavir that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Salatrim’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Salatrim side to compare — that is a limit of the record, not a statement that Salatrim has no side effects.

How to take them

Some tipranavir Products Have a Food Rule — Salatrim Should Not Break It

At least one FDA label for a product containing tipranavir says to take it with food. If you take Salatrim on an empty stomach out of habit, keep them separate — and take tipranavir with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two tipranavir products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

( 2.2 ) APTIVUS taken with ritonavir tablets must be taken with meals ( 2.1 ) APTIVUS capsules must be swallowed whole and must not be opened or chewed ( 2.1 ) Children should be assessed for their ability to swallow capsules before prescribing APTIVUS capsules.

From the Dosage and Administration section of the FDA label we read for tipranavir — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With tipranavir

This page covers Salatrim only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the tipranavir page lists 212 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), 1,3-dmaa (moderate) and Acacia Rigidula (moderate).

By severity: 3 major · 165 moderate · 44 minor.

From our pharmacist’s overview on the tipranavir page

“Keeping tipranavir (Aptivus) at a steady blood level is what keeps HIV suppressed, so this is a supplement list that deserves genuine care, and the three major-rated entries come first. St.”

Reviewed by 2 · Jul 18, 2026

Open the tipranavir interaction page

How much people look this up

Where Salatrim and tipranavir Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Salatrim
Steady interest

#1,088 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication tipranavir
Steady interest

#1,797 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Salatrim is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Salatrim reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Salatrim and tipranavir records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Salatrim

What is Salatrim?

  • Reduced-calorie fat replacement in foods
  • Lower-calorie baked goods and confections
  • Reducing dietary fat calories
  • Food texture and mouthfeel similar to regular fat

Salatrim is a man-made, reduced-calorie fat used as an ingredient in processed foods, not a traditional herb or supplement you would take on its own. It is designed to provide fewer calories than ordinary fat, but eating large amounts may cause stomach and bowel discomfort. If you have questions about products containing it, check the food label and ask your pharmacist or doctor.

Not applicable (manufactured fat ingredient) · Reduced-fat or reduced-calorie processed foods such as baked goods, chocolate, confections, and dairy-type products

An interaction check asks whether these two react with each other — it does not ask whether Salatrim is a good idea for someone in your situation. Here is what our Salatrim record says about it on its own.

Salatrim: dosing

There is no established supplement dose for Salatrim, because it is a food ingredient rather than a pill or capsule you would take by itself. The amount you get depends on the food product and how much of it you eat.If you choose foods made with Salatrim, follow the serving sizes listed on the food label and avoid eating very large amounts at once to lower the chance of digestive upset.

From our Salatrim monograph — the full record covers uses, side effects and every documented interaction.

Read the full Salatrim monograph & all interactions
Medication

About Tipranavir

What Is Tipranavir Used For?

Brand name: Aptivus

Aptivus (tipranavir) is used to treat HIV-1 infection in adults and in pediatric patients weighing 36 kg or more who have already tried other HIV medications and whose virus has become resistant to more than one protease inhibitor. It must always be taken together with ritonavir to work properly.

Aptivus is not recommended for people who have never been treated for HIV before. It works best when combined with other active HIV medications, and a resistance test is usually done first to confirm the virus will respond to it.

See full Tipranavir drug information
Keep checking

Other Drugs & Salatrim

Browse every other medication we’ve checked against Salatrim — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Salatrim against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Salatrim list.

See the full Salatrim interactions page
See every supplement checked against tipranavir, ranked by severity
Evidence & sources

Salatrim References

The 2 sources that drive our Salatrim monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Salatrim is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Food Additives & Ingredients — U.S. Food and Drug Administration Source
  2. Fat Replacers — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Salatrim and tipranavir Together: Common Questions

Is it safe to take Salatrim with tipranavir?
We do not list a known interaction between Salatrim and tipranavir. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Salatrim and tipranavir at the same time of day?
At least one FDA label for a product containing tipranavir says to take it with food. If you take Salatrim on an empty stomach out of habit, keep them separate and take tipranavir with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two tipranavir products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does tipranavir interact with any supplements?
Yes. tipranavir has documented interactions with 212 supplements in our database — Salatrim is not one of them. The tipranavir interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Salatrim monograph Uses, safety profile, and every drug interaction in one place Tipranavir drug information The full plain-English guide to this medication tipranavir supplement interactions Every supplement checked against tipranavir, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About tipranavir and Salatrim?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.