Drug & supplement interaction

Scarlet Pimpernel + Nevirapine

Nevirapine brand names: Viramune, Viramune XR.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Scarlet Pimpernel and Nevirapine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Scarlet Pimpernel and Nevirapine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Nevirapine and Scarlet Pimpernel in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Scarlet Pimpernel at all — not against Nevirapine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Scarlet Pimpernel safety at a glance

Scarlet Pimpernel overall Use caution It contains potentially toxic compounds and is not well studied, so internal use is generally discouraged.
Pregnancy Likely Unsafe When used orally or topically long-term. Scarlet pimpernel shows evidence of uterine stimulant activity. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or topically long-term; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Nevirapine and Scarlet Pimpernel? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Nevirapine’s Own FDA Label Lists

This is not an interaction — none of it involves Scarlet Pimpernel. These are the most notable effects listed in the ADVERSE REACTIONS section of Nevirapine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 4 of them are worth acting on rather than waiting out — marked below.

  • Yellowing of the skin or eyes Worth acting on
  • A severe skin reaction Worth acting on
  • Liver problems Worth acting on
  • An allergic reaction Worth acting on
  • Joint pain
  • Reduced appetite
  • Fever
  • Itching
  • Swelling
  • Stomach pain

Showing the 10 most notable of 16 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Nevirapine. Read the label on DailyMed › Scarlet Pimpernel’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Scarlet Pimpernel side to compare — that is a limit of the record, not a statement that Scarlet Pimpernel has no side effects.

Special populations

Scarlet Pimpernel in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally or topically long-term. Scarlet pimpernel shows evidence of uterine stimulant activity.

Lactation Possibly Unsafe

When used orally or topically long-term; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Nevirapine

This page covers Scarlet Pimpernel only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Nevirapine page lists 180 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 137 moderate · 37 minor.

From our pharmacist’s overview on the Nevirapine page

“St. John's wort is the interaction to understand first.”

Reviewed by 2 · Jul 18, 2026

Open the Nevirapine interaction page

How much people look this up

Where Scarlet Pimpernel and Nevirapine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Scarlet Pimpernel
Steady interest

#1,298 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Nevirapine
Top half

#997 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Scarlet Pimpernel reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Scarlet Pimpernel and Nevirapine records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Scarlet Pimpernel

What is Scarlet Pimpernel?

  • Skin conditions and wounds
  • Liver and gallbladder complaints
  • Respiratory ailments
  • Mild mood or 'melancholy' (folk use)
  • Urinary complaints

Scarlet Pimpernel is a small wild flowering plant with a long history in folk medicine, but there is very little modern scientific evidence to support any of its uses. It contains compounds called saponins that can be irritating and potentially toxic, so it is generally not recommended for internal use. If you are considering it, talk with a pharmacist or doctor first.

Lysimachia arvensis · Primulaceae · Aerial parts (leaves, flowers, and stems) · Dried herb, tinctures, infusions, and topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Scarlet Pimpernel is a good idea for someone in your situation. Here is what our Scarlet Pimpernel record says about it on its own.

Scarlet Pimpernel: dosing

There is no established, standardized safe dose for Scarlet Pimpernel. Because of its potential toxicity and the lack of quality research, no specific milligram amount can be recommended.If you find a commercial product, follow the label directions exactly and do not exceed them.

From our Scarlet Pimpernel monograph — the full record covers uses, side effects and every documented interaction.

Read the full Scarlet Pimpernel monograph & all interactions
Medication

About Nevirapine

What Is Nevirapine Used For?

Brand names: Viramune, Viramune XR

Nevirapine is used alongside other antiretroviral medicines to treat HIV-1 infection. It is not a cure, but it helps suppress the virus when used as part of a combination regimen.

The immediate-release tablet is approved for adults and pediatric patients 15 days and older. The extended-release tablet is approved for adults and for pediatric patients 6 years of age or older who meet a minimum body surface area requirement. The oral suspension is approved for adults and pediatric patients 15 days and older. None of these formulations should be used alone to treat HIV-1, and none are approved for post-exposure prophylaxis (PEP).

See full Nevirapine drug information
Keep checking

Other Drugs & Scarlet Pimpernel

Browse every other medication we’ve checked against Scarlet Pimpernel — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Scarlet Pimpernel References

The 1 references that drive our Scarlet Pimpernel monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Scarlet Pimpernel and Nevirapine Together: Common Questions

Is it safe to take Scarlet Pimpernel with Nevirapine?
We do not list a known interaction between Scarlet Pimpernel and Nevirapine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Nevirapine interact with any supplements?
Yes. Nevirapine has documented interactions with 180 supplements in our database — Scarlet Pimpernel is not one of them. The Nevirapine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Nevirapine and Scarlet Pimpernel?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.