Scotch Thistle + Clindamycin , Benzoyl peroxide
Clindamycin , Benzoyl peroxide brand names: BenzaClin, Duac Once Daily.
We found no known interaction between Scotch Thistle and Clindamycin , Benzoyl peroxide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Scotch Thistle and Clindamycin , Benzoyl peroxide
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Clindamycin , Benzoyl peroxide and Scotch Thistle in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Scotch Thistle at all — not against Clindamycin , Benzoyl peroxide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Scotch Thistle safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Clindamycin , Benzoyl peroxide
This page covers Scotch Thistle only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Clindamycin , Benzoyl peroxide page lists 3 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate) and Alchemilla (minor).
By severity: 2 moderate · 1 minor.
From our pharmacist’s overview on the Clindamycin , Benzoyl peroxide page
“Because clindamycin and benzoyl peroxide (BenzaClin, Duac) is an acne gel that works at the skin surface, every supplement interaction on file involves other things applied to the skin, not pills you swallow. The one to know is DMSO, which appears to raise how much of a topical drug soaks through, so it can amplify both the gel's effec…”
Reviewed by 2 · Jul 18, 2026
Where Scotch Thistle and Clindamycin , Benzoyl peroxide Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#860 of 1,452 supplements looked up here in the last 7 days
#1,052 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Scotch Thistle is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Scotch Thistle reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Scotch Thistle and Clindamycin , Benzoyl peroxide records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Scotch Thistle
What is Scotch Thistle?
- Digestive upset
- Liver and gallbladder support
- Mild diuretic
- Skin sores and wound care (traditional/topical)
- General tonic
Scotch Thistle is a tall, spiny plant used in folk medicine for digestion, liver complaints, and as a mild diuretic, but there is very little modern scientific evidence to support these uses. Because reliable safety and dosing information is lacking, it is best to talk with a pharmacist or doctor before trying it, and to avoid it during pregnancy and breastfeeding.
Onopordum acanthium · Asteraceae · Aerial parts (flowers, leaves, stems) and roots; sometimes seeds · Tea (dried herb infusion), tincture, capsules, dried herb
An interaction check asks whether these two react with each other — it does not ask whether Scotch Thistle is a good idea for someone in your situation. Here is what our Scotch Thistle record says about it on its own.
Scotch Thistle: dosing
There is no established, standardized dose for Scotch Thistle. Because it has not been well studied in people, safe and effective amounts are simply not known.If you choose to use a commercial product, follow the directions on the label and do not exceed the recommended amount.
From our Scotch Thistle monograph — the full record covers uses, side effects and every documented interaction.
Other Drugs & Scotch Thistle
Browse every other medication we’ve checked against Scotch Thistle — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Scotch Thistle against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Scotch Thistle list.
Scotch Thistle References
The 2 sources that drive our Scotch Thistle monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Scotch Thistle is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- Herbs and Supplements — MedlinePlus (U.S. National Library of Medicine) Source
- Using Dietary Supplements Wisely — NIH National Center for Complementary and Integrative Health (NCCIH) Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Scotch Thistle and Clindamycin , Benzoyl peroxide Together: Common Questions
Is it safe to take Scotch Thistle with Clindamycin , Benzoyl peroxide?
Does Clindamycin , Benzoyl peroxide interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.