Drug & supplement interaction

Scurvy Grass + Roflumilast

Roflumilast brand names: Daliresp, Zoryve.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Scurvy Grass and Roflumilast in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Scurvy Grass and Roflumilast

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Roflumilast and Scurvy Grass in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Scurvy Grass at all — not against Roflumilast, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Scurvy Grass safety at a glance

Scurvy Grass overall Use caution Generally eaten as a food historically, but modern safety data for medicinal use is limited.
Pregnancy Avoid Not enough safety information; avoid medicinal amounts during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid medicinal amounts while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Roflumilast and Scurvy Grass? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Roflumilast’s Own FDA Label Lists

This is not an interaction — none of it involves Scurvy Grass. These are the most notable effects listed in the ADVERSE REACTIONS section of Roflumilast’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 2 of them are worth acting on rather than waiting out — marked below.

  • Hives Worth acting on
  • A higher chance of infection Worth acting on
  • A stuffy or runny nose
  • Trouble sleeping
  • Diarrhea
  • A skin rash
  • Vomiting
  • Headache
  • Nausea

From the ADVERSE REACTIONS section of the FDA label for Roflumilast. Read the label on DailyMed › Scurvy Grass’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Scurvy Grass side to compare — that is a limit of the record, not a statement that Scurvy Grass has no side effects.

Everything else you take

See Every Supplement That Interacts With Roflumilast

This page covers Scurvy Grass only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Roflumilast page lists 141 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 96 moderate · 42 minor.

From our pharmacist’s overview on the Roflumilast page

“Roflumilast (Daliresp for severe COPD, Zoryve as a cream for skin conditions) is cleared almost entirely by one liver enzyme, CYP3A4, which is why 121 of the 141 supplements on this page can push its level up or down, and why real caution is warranted here. Start with the three rated major: grapefruit blocks that enzyme and can raise r…”

Reviewed by 2 · Jul 18, 2026

Open the Roflumilast interaction page

How much people look this up

Where Scurvy Grass and Roflumilast Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Scurvy Grass
Top half

#532 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Roflumilast
Top half

#1,253 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Scurvy Grass reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Scurvy Grass and Roflumilast records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Scurvy Grass

What is Scurvy Grass?

  • Historical scurvy prevention (vitamin C source)
  • General tonic
  • Mouth and gum health
  • Digestive support
  • Mild antiseptic/wound rinse

Scurvy grass is a traditional European herb historically eaten by sailors as a source of vitamin C to prevent scurvy. Today it has little proven medical use beyond its vitamin C content, and modern research is very limited. If you simply need vitamin C, well-studied foods and supplements are more reliable.

Cochlearia officinalis · Brassicaceae · Leaves and aerial parts (fresh herb) · Fresh leaves, tea, tincture, juice, dried herb

An interaction check asks whether these two react with each other — it does not ask whether Scurvy Grass is a good idea for someone in your situation. Here is what our Scurvy Grass record says about it on its own.

Scurvy Grass: dosing

There is no established standardized dose for scurvy grass. Historically it was used as a fresh leafy green or its juice, in everyday food-like amounts, rather than measured medicinal doses.If you use a commercial product such as a tea or tincture, follow the directions on the label and do not exceed the suggested amount.

From our Scurvy Grass monograph — the full record covers uses, side effects and every documented interaction.

Read the full Scurvy Grass monograph & all interactions
Medication

About Roflumilast

What Is Roflumilast Used For?

Brand names: Daliresp, Zoryve

Daliresp and roflumilast tablets are used to reduce the risk of COPD (chronic obstructive pulmonary disease) flare-ups in adults with severe COPD linked to chronic bronchitis who have had flare-ups in the past. They are not rescue inhalers and will not relieve a sudden breathing attack.

Zoryve cream is used topically to treat plaque psoriasis (adults and children 2+) and mild to moderate atopic dermatitis (eczema) in adults and children as young as 2. Zoryve topical foam is used to treat seborrheic dermatitis (adults and children 9+) and plaque psoriasis of the scalp and body (adults and children 12+).

Most-Reported Side Effects for Roflumilast

From FAERS, the FDA’s public side-effect reporting system (6,927 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 1,054 reports
Chronic obstructive pulmonary disease 657 reports
Diarrhea 596 reports
Nausea 491 reports
Pneumonia 476 reports
See full Roflumilast drug information
Keep checking

Other Drugs & Scurvy Grass

Browse every other medication we’ve checked against Scurvy Grass — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Scurvy Grass References

The 1 references that drive our Scurvy Grass monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Scurvy Grass and Roflumilast Together: Common Questions

Is it safe to take Scurvy Grass with Roflumilast?
We do not list a known interaction between Scurvy Grass and Roflumilast. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Roflumilast interact with any supplements?
Yes. Roflumilast has documented interactions with 141 supplements in our database — Scurvy Grass is not one of them. The Roflumilast interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Roflumilast and Scurvy Grass?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.