Drug & supplement interaction

Sweet Almond + Dextromethorphan HBr, Phenylephrine HCl

Dextromethorphan HBr, Phenylephrine HCl brand name: Vicks Formula 44D Cough & Head Congestion Relief.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Sweet Almond and Dextromethorphan HBr, Phenylephrine HCl in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Sweet Almond and Dextromethorphan HBr, Phenylephrine HCl

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Dextromethorphan HBr, Phenylephrine HCl and Sweet Almond in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Sweet Almond at all — not against Dextromethorphan HBr, Phenylephrine HCl, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Sweet Almond safety at a glance

Sweet Almond overall Generally safe Generally safe as a food for most people, but a serious allergy risk for those with tree-nut allergy.
Pregnancy Generally safe Eating almonds as a normal food is considered safe in pregnancy if you are not allergic.
Breastfeeding Generally safe Eating almonds as a normal food is considered safe while breastfeeding if you are not allergic.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Dextromethorphan HBr, Phenylephrine HCl and Sweet Almond? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Sweet Almond Itself Has Been Linked To

This is not an interaction — nothing below involves Dextromethorphan HBr, Phenylephrine HCl. It is the side-effect record for Sweet Almond on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Sweet Almond, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • An allergic reaction Worth acting on Additional detail

    “Tree nuts, which include almonds, can cause allergic reactions in sensitive individuals. Due to the prevalence of this allergy in the general population, tree nuts are classified as a major food allergen in the United States.”

    Sweet Almond · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    1 source cited
    1. 105410. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor
  • Itching / A skin rash Additional detail

    “Topically, itching, dermatitis, and worsening eczema have been reported in a clinical trial.”

    Sweet Almond · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 101788. Simon D, Nobbe S, Nägeli M, et al. Short- and long-term effects of two emollients on itching and skin restoration in xerotic eczema. Dermatol Ther. 2018;31(6):e12692. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Sweet Almond — expand a row for the licensed statement it rests on. We haven’t matched Dextromethorphan HBr, Phenylephrine HCl to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Dextromethorphan HBr, Phenylephrine HCl.

Everything else you take

See Every Supplement That Interacts With Dextromethorphan HBr, Phenylephrine HCl

This page covers Sweet Almond only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dextromethorphan HBr, Phenylephrine HCl page lists 197 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Ephedra (major), Grapefruit (major), Lithium (major) and Peyote (major).

By severity: 8 major · 148 moderate · 41 minor.

From our pharmacist’s overview on the Dextromethorphan HBr, Phenylephrine HCl page

“The supplement interactions with Dextromethorphan HBr and Phenylephrine HCl (Vicks Formula 44D) deserve real respect, and the small cluster of major-rated ones should be understood before you reach for the bottle. Phenylephrine is a stimulant-type decongestant, so anything with caffeine (coffee, tea, cola nut) or ephedrine-like herbs s…”

Reviewed by 2 · Jul 18, 2026

Open the Dextromethorphan HBr, Phenylephrine HCl interaction page

One more smart check

Taking Sweet Almond as Part of a Dietary Supplement Product? Check It for Interactions

We hold 61 real supplement products containing Sweet Almond, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Sweet Almond. Even though Sweet Almond itself has no known interaction with Dextromethorphan HBr, Phenylephrine HCl, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Sweet Almond and Dextromethorphan HBr, Phenylephrine HCl Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Sweet Almond
Steady interest

#1,283 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dextromethorphan HBr, Phenylephrine HCl
Steady interest

#2,209 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Sweet Almond reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Sweet Almond and Dextromethorphan HBr, Phenylephrine HCl records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Sweet Almond

What is Sweet Almond?

  • Heart and cholesterol health
  • Skin moisturizing
  • Hair and scalp care
  • Constipation and digestive comfort
  • Nutritious snack and protein source

Sweet almonds are a nutritious tree nut rich in healthy fats, fiber, protein, vitamin E, and minerals, and they are generally safe and healthy to eat as part of a balanced diet. Almond oil is also widely used on the skin and hair. The main concern is tree-nut allergy, which can be serious; people with nut allergies should avoid almonds entirely.

Prunus dulcis · Rosaceae · Seed (nut) and oil pressed from the seed · Whole nuts, almond flour, almond milk, almond butter, almond oil (for skin and hair)

An interaction check asks whether these two react with each other — it does not ask whether Sweet Almond is a good idea for someone in your situation. Here is what our Sweet Almond record says about it on its own.

Sweet Almond: dosing

There is no official "dose" for sweet almonds because they are a food. In nutrition studies, a common amount is about a small handful (roughly an ounce) per day as part of a balanced diet, but this is a general guide, not a set medicine dose.For supplements, almond flour, or almond oil products, follow the directions on the label. A standardized medicinal dose has not been established.

From our Sweet Almond monograph — the full record covers uses, side effects and every documented interaction.

Read the full Sweet Almond monograph & all interactions
Medication

About Dextromethorphan HBr, Phenylephrine HCl

Most-Reported Side Effects for Dextromethorphan HBr, Phenylephrine HCl

From FAERS, the FDA’s public side-effect reporting system (966 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Covid-19 130 reports
Disease recurrence 106 reports
Nasopharyngitis 78 reports
Nausea 78 reports
Fatigue 73 reports
Keep checking

Other Drugs & Sweet Almond

Browse every other medication we’ve checked against Sweet Almond — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Sweet Almond References

The 4 references that drive our Sweet Almond monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Motaharifard MS, Effatpanah M, Karimi M, et al. Effect of sweet almond syrup versus methylphenidate in children with ADHD: A randomized triple-blind clinical trial. Complement Ther Clin Pract. 2019;36:170-175. PubMed
  2. Simon D, Nobbe S, Nägeli M, et al. Short- and long-term effects of two emollients on itching and skin restoration in xerotic eczema. Dermatol Ther. 2018;31(6):e12692. PubMed
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor
  4. Salama M, Tebben PJ, Al Nofal A. An infant developing hypercalcemia and hypophosphatemia due to the use of exclusively almond milk. J Pediatr Endocrinol Metab 2024;37(4):375-379. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Sweet Almond and Dextromethorphan HBr, Phenylephrine HCl Together: Common Questions

Is it safe to take Sweet Almond with Dextromethorphan HBr, Phenylephrine HCl?
We do not list a known interaction between Sweet Almond and Dextromethorphan HBr, Phenylephrine HCl. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Dextromethorphan HBr, Phenylephrine HCl interact with any supplements?
Yes. Dextromethorphan HBr, Phenylephrine HCl has documented interactions with 197 supplements in our database — Sweet Almond is not one of them. The Dextromethorphan HBr, Phenylephrine HCl interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Dextromethorphan HBr, Phenylephrine HCl and Sweet Almond?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.