Drug & supplement interaction

Threonine + Sacituzumab Govitecan-Hziy

Sacituzumab Govitecan-Hziy brand name: Trodelvy.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Threonine and Sacituzumab Govitecan-Hziy in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Threonine and Sacituzumab Govitecan-Hziy

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Sacituzumab Govitecan-Hziy and Threonine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Threonine safety at a glance

Threonine overall Use caution Threonine from food is safe; supplement safety at higher doses is not well studied.
Pregnancy Use caution Amounts from food are fine, but supplements have not been well studied in pregnancy, so avoid unless advised by a clinician.
Breastfeeding Use caution Dietary amounts are normal, but supplement use during breastfeeding has not been well studied.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Sacituzumab Govitecan-Hziy and Threonine? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Sacituzumab Govitecan-Hziy

Interactions in our licensed database are recorded against drug classes, not just single drug names. Sacituzumab Govitecan-Hziy is filed under a single classification — glucuronidated drugs. Threonine has documented interactions with 1 drug class — the most serious being nmda antagonists (major) — and none of Sacituzumab Govitecan-Hziy’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Threonine Does Interact With Other Medications

Threonine has 3 major, known drug interactions in our database — Sacituzumab Govitecan-Hziy isn’t one of them. If you take anything else, check it against the full list below.

Major 3 No known interaction 2,827 (incl. Sacituzumab Govitecan-Hziy)
Taking anything else?

Check Another of Your Medications Against Threonine

Covers the 2,830 medications we’ve checked against Threonine. Pick one to open its full report.

What to actually watch for

What Threonine Itself Has Been Linked To

This is not an interaction — nothing below involves Sacituzumab Govitecan-Hziy. It is the side-effect record for Threonine on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Threonine, this list is the first place to look.

  • Stomach upset / Constipation / Diarrhea Additional detail

    “Orally, some patients can experience minor gastrointestinal upset including diarrhea. Other side effects reported in people who have taken threonine include flatus and constipation.”

    Threonine · Natural Medicines adverse-effect record, reported in constipation.

    2 sources cited
    1. 12056. Lee A, Patterson V. A double blind study of L-threonine in patients with spinal spasticity. Acta Neurol Scand 1993;88:334-8. PubMed
    2. 681. Tandan R, Bromberg MB, Forshew D, et al. A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data. Neurology 1996;47:1220-6. PubMed
  • Headache Additional detail

    “Orally, headache has been reported in people who have taken threonine.”

    Threonine · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 681. Tandan R, Bromberg MB, Forshew D, et al. A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data. Neurology 1996;47:1220-6. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Threonine — expand a row for the licensed statement it rests on. We haven’t matched Sacituzumab Govitecan-Hziy to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Sacituzumab Govitecan-Hziy.

Everything else you take

See Every Supplement That Interacts With Sacituzumab Govitecan-Hziy

This page covers Threonine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Sacituzumab Govitecan-Hziy page lists 12 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Breadfruit (moderate), Brussels Sprout (moderate), Cabbage (moderate), Calcium D-glucarate (moderate) and Cannabidiol (cbd) (moderate).

By severity: 11 moderate · 1 minor.

Open the Sacituzumab Govitecan-Hziy interaction page

One more smart check

Taking Threonine as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,803 real supplement products containing Threonine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Threonine. Even though Threonine itself has no known interaction with Sacituzumab Govitecan-Hziy, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Threonine and Sacituzumab Govitecan-Hziy Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Threonine
Top 25%

#150 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Sacituzumab Govitecan-Hziy
Top 5%

#130 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Threonine reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Threonine and Sacituzumab Govitecan-Hziy records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Threonine

What is Threonine?

  • General amino acid/protein support
  • Muscle and tissue health
  • Immune support
  • Nervous system support (as a precursor)
  • Liver health (proposed)

Threonine is an essential amino acid your body needs but cannot make, so you must get it from food or supplements. Most people get plenty from a normal diet, and high-quality evidence for taking it as a separate supplement is limited. If you are considering threonine supplements, talk with your pharmacist or doctor first.

Amino acid (obtained from dietary protein or made synthetically) · Capsules, tablets, powder, and part of amino acid blends; also found in protein-rich foods

An interaction check asks whether these two react with each other — it does not ask whether Threonine is a good idea for someone in your situation. Here is what our Threonine record says about it on its own.

Threonine: dosing

There is no well-established standard supplement dose of threonine for general health. Studies that have used it for specific medical conditions used different amounts, and those doses were given under medical supervision.If you choose to use a threonine product, follow the directions on the label and do not exceed the recommended amount.

From our Threonine monograph — the full record covers uses, side effects and every documented interaction.

Read the full Threonine monograph & all interactions
Medication

About Sacituzumab govitecan-hziy Injection

What Is Sacituzumab govitecan-hziy Injection Used For?

Brand name: Trodelvy

  • Sacituzumab govitecan-hziy is used to treat ertain types of breast cancer in adults that has spread to other parts of the body or cannot be removed by surgery and who have already been treated with at least two other chemotherapy medications. Sacituzumab govitecan-hziy is also used to treat certain types of urothelial cancer (cancer of the lining of the bladder and other parts of the urinary tract) in adults that has spread to other parts of the body or cannot be removed by surgery and who have already been treated with at least two other chemotherapy medications. Sacituzumab govitecan-hziy is in a class of medications called antibody-drug conjugates. It works by killing cancer cells.

See full Sacituzumab govitecan-hziy Injection drug information
Keep checking

Other Drugs & Threonine

Browse every other medication we’ve checked against Threonine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

3Major
0Moderate
0Minor
2,826No known interaction
3 Major 2,826 No interaction
Major

3 interactions

No interaction 2,826 drugs checked — show the list

We also checked Threonine against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,826 medications checked with no known interaction — see the full Threonine list.

See the full Threonine interactions page
See every supplement checked against Sacituzumab Govitecan-Hziy, ranked by severity
Evidence & sources

Threonine References

The 4 references that drive our Threonine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Tandan R, Bromberg MB, Forshew D, et al. A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data. Neurology 1996;47:1220-6. PubMed
  2. Lee A, Patterson V. A double blind study of L-threonine in patients with spinal spasticity. Acta Neurol Scand 1993;88:334-8. PubMed
  3. Blin O, Pouget J, Aubrespy G, et al. A double-blind placebo controlled trial of L-threonine in amyotrophic lateral sclerosis. J Neurol 1992;239:79-81.
  4. Roufs JB. L-threonine as a symptomatic treatment for amyotrophic lateral sclerosis (ALS). Med Hypotheses 1991;34:20-3. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Threonine and Sacituzumab Govitecan-Hziy Together: Common Questions

Is it safe to take Threonine with Sacituzumab Govitecan-Hziy?
We do not list a known interaction between Threonine and Sacituzumab Govitecan-Hziy. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Threonine and Sacituzumab Govitecan-Hziy combination checked?
Interactions in our licensed database are recorded against drug classes. Sacituzumab Govitecan-Hziy is filed under 1 classification, and Threonine has documented interactions with 1 drug class — none of Sacituzumab Govitecan-Hziy's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Threonine interact with any other medications?
Yes. Threonine has 3 documented drug interactions in our database — Sacituzumab Govitecan-Hziy is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Sacituzumab Govitecan-Hziy interact with any supplements?
Yes. Sacituzumab Govitecan-Hziy has documented interactions with 12 supplements in our database — Threonine is not one of them. The Sacituzumab Govitecan-Hziy interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Threonine monograph Uses, safety profile, and every drug interaction in one place Sacituzumab govitecan-hziy Injection drug information The full plain-English guide to this medication Sacituzumab Govitecan-Hziy supplement interactions Every supplement checked against Sacituzumab Govitecan-Hziy, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Sacituzumab Govitecan-Hziy and Threonine?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.