Herb & supplement monograph

Hempnettle Drug Interactions, Uses, Effectiveness, Safety & More

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Interaction report

Drugs that interact with Hempnettle

0 medications have a known interaction with Hempnettle, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Hempnettle. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Hempnettle combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Hempnettle: Uses, Safety & Side Effects

The bottom line

Hempnettle is a traditional European herb that has been used as a tea for coughs and minor respiratory complaints, but there is very little modern scientific research to support these uses. Because its safety and effectiveness are not well studied, it is best to talk with a pharmacist or doctor before trying it, and to avoid it during pregnancy and breastfeeding.

Scientific name
Galeopsis tetrahit
Family
Lamiaceae
Part used
Aerial parts (flowering tops, leaves, and stems)
Common forms
Tea (infusion), liquid extract, dried herb
People commonly use it for
  • Coughs and chest congestion
  • Mild respiratory complaints
  • General tonic
  • Soothing irritated airways

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallLimited data

There is very little modern research on its safety or effective dose.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Hempnettle is a flowering plant in the mint family (Lamiaceae). The name is most often used for Galeopsis tetrahit, sometimes called common hempnettle. Despite the name, it is not related to cannabis (hemp) — the name comes from the shape of its leaves.

It grows as a weedy plant across much of Europe and parts of Asia, and it has spread to North America. It is often found in fields, along roadsides, and in disturbed soil.

In traditional European folk medicine, the dried above-ground parts of the plant were sometimes brewed into a tea and used for coughs and other minor breathing problems. Today it is uncommon as a supplement, and most uses are based on tradition rather than strong scientific study.

How it works

Hempnettle contains a mix of plant compounds, including iridoid glycosides, flavonoids, tannins, and some silica-containing substances. These types of compounds are common in many plants in the mint family.

In traditional use, the tannins and other compounds were thought to have a mild soothing or astringent effect that might ease throat irritation. Some lab studies suggest plant compounds like these can have antioxidant or mild antimicrobial activity in a test tube.

It is important to understand that these are mostly ideas based on the plant's chemistry and on laboratory or animal research. They do not prove that hempnettle has a meaningful effect in people when taken as a tea or supplement.

Effectiveness

Does Hempnettle work?

Evidence overview · 2 uses evaluated
2 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Hempnettle, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 2 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Cough
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral hempnettle for cough, there is insufficient reliable information about the clinical effects of hempnettle for this purpose.

Insufficient Reliable Evidence To Rate Respiratory tract infections
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral hempnettle for respiratory tract infections, there is insufficient reliable information about the clinical effects of hempnettle for this purpose.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

The safety of hempnettle has not been well studied in modern research. Because of this, its overall safety is best described as unknown. This does not mean it is dangerous, but it does mean we lack good information to confirm it is safe.

People with allergies to plants in the mint family may be more likely to react to it. Children, older adults, and people with chronic medical conditions should be especially cautious and check with a healthcare provider first.

Pregnancy and breastfeeding: There is not enough reliable information to consider hempnettle safe during pregnancy or while breastfeeding. To be safe, avoid using it during these times.

As with any herbal product, quality and purity can vary between brands, and products are not tightly regulated. Always talk with a pharmacist or doctor before starting hempnettle, especially if you take prescription medicines or have a health condition.

Side effects

There is little documented information about side effects from hempnettle. With herbal teas in general, possible mild effects can include stomach upset, nausea, or an allergic reaction such as rash or itching.

Because the plant has not been carefully studied, rare or serious side effects cannot be ruled out. Stop using it and seek medical care if you notice signs of an allergic reaction, such as swelling, trouble breathing, or a spreading rash.

Dosing

There is no established, science-based dose for hempnettle. A standard safe and effective amount has not been determined in research.

If you choose to use a product that contains it, follow the directions on the product label and do not exceed the suggested amount. Because doses and product strengths vary widely, it is a good idea to review the product with a pharmacist before using it.

Pregnancy & Breastfeeding

Hempnettle & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Hempnettle & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 2 sources that drive our Hempnettle monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.

  1. Herbs at a Glance — NIH NCCIH Source
  2. Herbs and Supplements — MedlinePlus Source
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Brand directory

Brands that make products with Hempnettle

1 brand in our database make a supplement containing Hempnettle.

Pharmacist Counseling Corner

Hempnettle: Common Questions

What is Hempnettle used for, and does it work?
People use Hempnettle for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Hempnettle interact with prescription medications?
We do not currently list any known drug interactions for Hempnettle. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Hempnettle interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Hempnettle with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Hempnettle interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
Is Hempnettle related to marijuana or hemp?
No. Despite its name, Hempnettle is a member of the mint family and is not related to cannabis. The 'hemp' in its name refers to the shape of its leaves, not to any cannabis content.
What do people use Hempnettle for?
Traditionally it has been brewed as a tea for coughs, chest congestion, and minor respiratory complaints. However, there is very little scientific evidence that it actually works for these uses.
Is Hempnettle safe to take?
Its safety has not been well studied, so it is considered unknown. Talk with a pharmacist or doctor before trying it, especially if you have a health condition or take other medicines.
Can I take Hempnettle while pregnant or breastfeeding?
No reliable safety information is available, so it is best to avoid Hempnettle during pregnancy and while breastfeeding.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Products that contain Hempnettle

A rotating sample of real supplements in our database that list Hempnettle — open any to see its full ingredients and every drug interaction we check.

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