Drug & supplement interaction

Transcutaneous Electrical Acustimulation + Alvimopan

Alvimopan brand name: Entereg.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Transcutaneous Electrical Acustimulation and Alvimopan in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Transcutaneous Electrical Acustimulation and Alvimopan

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Alvimopan and Transcutaneous Electrical Acustimulation in our sources. This does not guarantee that the combination is completely free of risk — research on Transcutaneous Electrical Acustimulation alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Transcutaneous Electrical Acustimulation at all — not against Alvimopan, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Transcutaneous Electrical Acustimulation is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Transcutaneous Electrical Acustimulation safety at a glance

Transcutaneous Ele... overall Use caution Generally well tolerated, but it should be avoided by people with pacemakers and used under guidance.
Pregnancy Use caution Use during pregnancy is not well studied and should only be done with medical supervision.
Breastfeeding Not established There is little research on its use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Alvimopan and Transcutaneous Electrical Acustimulation? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Transcutaneous Electrical Acustimulation Itself Has Been Linked To

This is not an interaction — nothing below involves Alvimopan. It is the side-effect record for Transcutaneous Electrical Acustimulation on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Transcutaneous Electrical Acustimulation, this list is the first place to look.

  • Trouble sleeping Additional detail

    “Insomnia and temporary hand paralysis have been reported in one person each in a clinical trial.”

    Transcutaneous Electrical Acustimulation · Natural Medicines adverse-effect record, reported in insomnia.

    1 source cited
    1. 104742. Song Y, Xue X, Han H, et al. Efficacy of transcutaneous electrical acupoint stimulation combined with diazepam for acute alcohol withdrawal syndrome: A double-blind randomized sham-controlled trial. J Int Med Res. 2020;48(4):300060520910052. PubMed
  • Itching / Swelling Additional detail

    “Itchiness, skin redness, and swelling have been reported rarely in clinical research.”

    Transcutaneous Electrical Acustimulation · Natural Medicines adverse-effect record, reported in rosacea.

    6 sources cited
    1. 104735. Chen J, Tu Q, Miao S, Zhou Z, Hu S. Transcutaneous electrical acupoint stimulation for preventing postoperative nausea and vomiting after general anesthesia: A meta-analysis of randomized controlled trials. Int J Surg. 2020;73:57-64. PubMed
    2. 104741. Szmit M, Agrawal S, Gozdzik W, et al. Transcutaneous electrical acupoint stimulation reduces postoperative analgesic requirement in patients undergoing inguinal hernia repair: A randomized, placebo-controlled study. J Clin Med. 2021;10(1):146. PubMed
    3. 104742. Song Y, Xue X, Han H, et al. Efficacy of transcutaneous electrical acupoint stimulation combined with diazepam for acute alcohol withdrawal syndrome: A double-blind randomized sham-controlled trial. J Int Med Res. 2020;48(4):300060520910052. PubMed
    4. 107054. Xie J, Chen LH, Ning ZY, et al. Effect of transcutaneous electrical acupoint stimulation combined with palonosetron on chemotherapy-induced nausea and vomiting: a single-blind, randomized, controlled trial. Chin J Cancer 2017;36(1):6. PubMed
    5. 107056. Kabalak AA, Akcay M, Akcay F, Gogus N. Transcutaneous electrical acupoint stimulation versus ondansetron in the prevention of postoperative vomiting following pediatric tonsillectomy. J Altern Complement Med 2005;11(3):407-13. DOI
    6. 107060. Xiong Q, Min S, Wei K, et al. Transcutaneous electrical acupoint stimulation combined with dexamethasone and tropisetron prevents postoperative nausea and vomiting in female patients undergoing laparoscopic sleeve gastrectomy: a prospective, randomized co

Everything above comes from the Natural Medicines adverse-effect record for Transcutaneous Electrical Acustimulation — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Alvimopan’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Alvimopan column appears here.

Overlapping uses

What Alvimopan Is Prescribed For, and What Transcutaneous Electrical Acustimulation Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Alvimopan is a prescription medicine with approved uses on its FDA label. Transcutaneous Electrical Acustimulation is a treatment: what follows is what researchers have looked at it for, and how strong that evidence is.

Alvimopan is prescribed for: Alvimopan capsules are used in hospitals to help the digestive tract recover more quickly after surgery that involves removing part of the bowel (partial bowel resection with primary anastomosis — meaning the remaining ends are reconnected). After this type of surgery, the bowel often temporarily stops working, a condition called postoperative ileus. This medication is only given during a short hospital stay and is not for long-term or home use.

Transcutaneous Electrical Acustimulation has been studied for:

  • Postoperative ileus Natural Medicines rates the evidence for Transcutaneous Electrical Acustimulation: Possibly Effective Read what the research shows

    Transcutaneous Electrical Acustimulation for postoperative ileus

    Acustimulation seems to be effective for postoperative ileus.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Alvimopan on your own; if you are taking Transcutaneous Electrical Acustimulation for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Alvimopan

This page covers Transcutaneous Electrical Acustimulation only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Alvimopan page lists 54 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), St. John's Wort (major), Bitter Melon (moderate), Black Pepper (moderate) and Bulbine Natalensis (moderate).

By severity: 2 major · 35 moderate · 17 minor.

From our pharmacist’s overview on the Alvimopan page

“Alvimopan (Entereg) is given for a few days after bowel surgery to help the gut start moving again, and its supplement list warrants genuine care, with two entries rated major. St.”

Reviewed by 2 · Jul 18, 2026

Open the Alvimopan interaction page

How much people look this up

Where Transcutaneous Electrical Acustimulation and Alvimopan Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Transcutaneous Electrical Acustimulation
Steady interest

#1,380 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Alvimopan
Top 10%

#270 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Transcutaneous Electrical Acustimulation reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Transcutaneous Electrical Acustimulation and Alvimopan records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Transcutaneous Electrical Acustimulation

What is Transcutaneous Electrical Acustimulation?

  • Nausea and vomiting
  • Indigestion and functional dyspepsia
  • Constipation and bowel motility
  • Pain relief
  • Anxiety and stress
  • Post-operative recovery support

Transcutaneous Electrical Acustimulation (TEA) is not a herb or supplement but a non-drug therapy that applies mild electrical pulses through skin pads placed over traditional acupuncture points. It is being studied mostly for nausea, digestive problems, and pain, but the evidence is still early and mixed. Talk to your doctor or pharmacist before trying it, especially if you have a pacemaker or other implanted device.

Not applicable (this is a device-based therapy, not a plant or supplement) · Skin-surface electrode pads connected to a small electrical stimulator unit

An interaction check asks whether these two react with each other — it does not ask whether Transcutaneous Electrical Acustimulation is a good idea for someone in your situation. Here is what our Transcutaneous Electrical Acustimulation record says about it on its own.

Transcutaneous Electrical Acustimulation: dosing

There is no single standard "dose" for TEA. Settings vary widely between studies and devices, including the placement of the pads, the strength of the electrical pulses, the frequency, and how long and how often it is used.If you have a TEA device, follow the manufacturer's instructions for pad placement, intensity, and session length. Do not turn the intensity up to a painful level.

From our Transcutaneous Electrical Acustimulation monograph — the full record covers uses, side effects and every documented interaction.

Read the full Transcutaneous Electrical Acustimulation monograph & all interactions
Medication

About Alvimopan

What Is Alvimopan Used For?

Brand name: Entereg

Alvimopan capsules are used in hospitals to help the digestive tract recover more quickly after surgery that involves removing part of the bowel (partial bowel resection with primary anastomosis — meaning the remaining ends are reconnected). After this type of surgery, the bowel often temporarily stops working, a condition called postoperative ileus.

This medication is only given during a short hospital stay and is not for long-term or home use.

Most-Reported Side Effects for Alvimopan

From FAERS, the FDA’s public side-effect reporting system (43 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hospitalisation 19 reports
Acute kidney injury 5 reports
Acute myocardial infarction 4 reports
Ileus 3 reports
Pruritus 3 reports
See full Alvimopan drug information
Keep checking

Other Drugs & Transcutaneous Electrical Acustimulation

Browse every other medication we’ve checked against Transcutaneous Electrical Acustimulation — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Transcutaneous Electrical Acustimulation References

The 8 references that drive our Transcutaneous Electrical Acustimulation monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Chen J, Tu Q, Miao S, Zhou Z, Hu S. Transcutaneous electrical acupoint stimulation for preventing postoperative nausea and vomiting after general anesthesia: A meta-analysis of randomized controlled trials. Int J Surg. 2020;73:57-64. PubMed
  2. Szmit M, Agrawal S, Gozdzik W, et al. Transcutaneous electrical acupoint stimulation reduces postoperative analgesic requirement in patients undergoing inguinal hernia repair: A randomized, placebo-controlled study. J Clin Med. 2021;10(1):146. PubMed
  3. Song Y, Xue X, Han H, et al. Efficacy of transcutaneous electrical acupoint stimulation combined with diazepam for acute alcohol withdrawal syndrome: A double-blind randomized sham-controlled trial. J Int Med Res. 2020;48(4):300060520910052. PubMed
  4. Ma D, Han JS, Diao QH, et al. Transcutaneous electrical acupoint stimulation for the treatment of withdrawal syndrome in heroin addicts. Pain Med 2015;16(5):839-48. PubMed
  5. Xie J, Chen LH, Ning ZY, et al. Effect of transcutaneous electrical acupoint stimulation combined with palonosetron on chemotherapy-induced nausea and vomiting: a single-blind, randomized, controlled trial. Chin J Cancer 2017;36(1):6. PubMed
  6. Kabalak AA, Akcay M, Akcay F, Gogus N. Transcutaneous electrical acupoint stimulation versus ondansetron in the prevention of postoperative vomiting following pediatric tonsillectomy. J Altern Complement Med 2005;11(3):407-13. DOI
  7. Xiong Q, Min S, Wei K, et al. Transcutaneous electrical acupoint stimulation combined with dexamethasone and tropisetron prevents postoperative nausea and vomiting in female patients undergoing laparoscopic sleeve gastrectomy: a prospective, randomized co
  8. Xuan JL, Zhu YW, Xu WH, Zhao H, Chen JDZ, Wu GJ, Gong L. Integrative effects of transcutaneous electrical acustimulation on abdominal pain, gastrointestinal motility, and inflammation in patients with early-stage acute pancreatitis. Neurogastroenterol Mot PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Transcutaneous Electrical Acustimulation While Taking Alvimopan: Common Questions

Is it safe to have Transcutaneous Electrical Acustimulation while taking Alvimopan?
We do not list a known interaction between Transcutaneous Electrical Acustimulation and Alvimopan. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Transcutaneous Electrical Acustimulation and Alvimopan used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Transcutaneous Electrical Acustimulation in each. That is a conversation for your prescriber, especially if Alvimopan is being adjusted to a target.
Does Alvimopan interact with any supplements?
Yes. Alvimopan has documented interactions with 54 supplements in our database — Transcutaneous Electrical Acustimulation is not one of them. The Alvimopan interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Alvimopan and Transcutaneous Electrical Acustimulation?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.