Tylophora + Suvorexant
Suvorexant brand name: Belsomra.
We found no known interaction between Tylophora and Suvorexant in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Tylophora and Suvorexant
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Suvorexant and Tylophora in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Tylophora at all — not against Suvorexant, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Tylophora safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Questions About Tylophora or Suvorexant
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Tylophora or Suvorexant, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Suvorexant
This page covers Tylophora only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Suvorexant page lists 195 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Grapefruit (major).
By severity: 9 major · 147 moderate · 39 minor.
From our pharmacist’s overview on the Suvorexant page
“People take suvorexant (Belsomra) to fall asleep, and the supplements they reach for often promise the same thing, which is exactly the trouble. Of the 195 ingredients with an interaction on file, 78 add their own sedation on top of the drug's, and that theme dominates the 9 rated major, alcohol in any form among them.”
Reviewed by 2 · Jul 18, 2026
Where Tylophora and Suvorexant Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,126 of 1,452 supplements looked up here in the last 7 days
#1,666 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tylophora reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Tylophora and Suvorexant records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Tylophora
What is Tylophora?
- Asthma
- Allergies and hay fever
- Bronchitis and respiratory complaints
- Inflammatory conditions
- Digestive upset
Tylophora is a climbing plant used in traditional Indian (Ayurvedic) medicine, most often for asthma and breathing problems. Some older, small studies suggested possible benefit for asthma, but the evidence is weak and limited, and the plant can cause notable side effects. Talk to your pharmacist or doctor before trying it, and never use it to replace proven asthma treatments.
Tylophora indica · Apocynaceae · Leaves and roots · Capsules, dried leaf powder, tinctures, and traditional leaf preparations
An interaction check asks whether these two react with each other — it does not ask whether Tylophora is a good idea for someone in your situation. Here is what our Tylophora record says about it on its own.
Tylophora: dosing
There is no well-established or standardized dose for Tylophora. Older studies used small amounts of dried leaf for short periods, but these doses have not been confirmed as safe or effective.If you choose to use a product, follow the directions on the label and do not exceed them.
From our Tylophora monograph — the full record covers uses, side effects and every documented interaction.
About Suvorexant
What Is Suvorexant Used For?
Brand name: Belsomra
Belsomra (suvorexant) is used to treat insomnia — specifically, difficulty falling asleep and/or difficulty staying asleep through the night.
Most-Reported Side Effects for Suvorexant
From FAERS, the FDA’s public side-effect reporting system (12,888 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Tylophora
Browse every other medication we’ve checked against Tylophora — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Tylophora against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Warfarin ›
- Methylphenidate ›
- Sertraline ›
- Abemaciclib ›
- Ivermectin ›
- Testosterone ›
- Acetaminophen ›
- Losartan Potassium ›
- Aspirin ›
- Rosuvastatin ›
- Metoprolol ›
- Clopidogrel ›
- Escitalopram ›
- Rivaroxaban ›
- Atorvastatin ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Warfarin Sodium ›
- Tadalafil ›
- Sumatriptan ›
- Valacyclovir ›
- Hydroxyurea ›
- Semaglutide ›
- Prednisone ›
- Amitriptyline ›
- Propranolol ›
- Metformin ›
- Lisdexamfetamine ›
- Isotretinoin ›
- Amoxicillin ›
- Methotrexate ›
- Lisinopril ›
- Amlodipine Besylate ›
- Amphetamine ›
- Bendamustine ›
- Bupropion ›
- Fluoxetine ›
- Doxycycline ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Levothyroxine, Liothyronine ›
- Acetaminophen, Codeine ›
- Naproxen ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Duloxetine ›
- Methylene Blue ›
- Letrozole ›
- Citalopram ›
- Buspirone ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Tylophora list.
Tylophora References
The 6 references that drive our Tylophora monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Thiruvengadam KV, Haranath K, Sudarsan S, et al. Tylophora indica in bronchial asthma (a controlled comparison with a standard anti-asthmatic drug). J Indian Med Assoc 1978;71(7):172-176.
- Mathew KK, Shivpuri DN. Treatment of asthma with alkaloids of Tylophora indica - a double blind study. Aspects of Allergy Appl Immunol 1974;7:166-179.
- Gupta S, George P, Gupta V, et al. Tylophora indica in bronchial asthma--a double blind study. Indian J Med Res 1979;69:981-989.
- Shivpuri DN, Menon MP, Prakash D. A crossover double-blind study on Tylophora indica in the treatment of asthma and allergic rhinitis. J Allergy 1969;43(3):145-150.
- Shivpuri DN, Menon MP, Parkash D. Preliminary studies in Tylophora indica in the treatment of asthma and allergic rhinitis. J Assoc Physicians India 1968;16(1):9-15.
- Shivpuri DN, Singhal SC, Parkash D. Treatment of asthma with an alcoholic extract of tylophora indica: a cross-over, double-blind study. Ann Allergy 1972;30(7):407-412.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Tylophora and Suvorexant Together: Common Questions
Is it safe to take Tylophora with Suvorexant?
Does Suvorexant interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.