Drug & supplement interaction

Tyrosine + Carfilzomib

Carfilzomib brand name: Kyprolis.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Tyrosine and Carfilzomib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Tyrosine and Carfilzomib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Carfilzomib and Tyrosine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Tyrosine safety at a glance

Tyrosine overall Use caution Generally well tolerated in healthy adults, but talk to a healthcare provider before regular use.
Pregnancy Use caution Not enough safety data; avoid supplemental doses unless a doctor advises otherwise.
Breastfeeding Use caution Not enough safety data, so caution is advised while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Carfilzomib and Tyrosine? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Carfilzomib

Interactions in our licensed database are recorded against drug classes, not just single drug names. Carfilzomib is filed under a single classification — hepatotoxic drugs. Tyrosine has documented interactions with 2 drug classes — the most serious being levodopa (moderate) and thyroid hormone (moderate) — and none of Carfilzomib’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Tyrosine Does Interact With Other Medications

Tyrosine has 21 moderate known drug interactions in our database — Carfilzomib isn’t one of them. If you take anything else, check it against the full list below.

Moderate 21 No known interaction 2,809 (incl. Carfilzomib)
Taking anything else?

Check Another of Your Medications Against Tyrosine

Covers the 2,830 medications we’ve checked against Tyrosine. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Tyrosine and Carfilzomib May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Anxiety or restlessness Additional detail

    Tyrosine

    “Orally, larger doses of tyrosine (150 mg/kg) can cause headache and fatigue. Taking a combination of tyrosine 4 grams, 5-hydroxytryptophan 800 mg, and carbidopa 100 mg can cause drowsiness and agitation. These effects can be mitigated by lowering the dosage.”

    Tyrosine · Natural Medicines adverse-effect record, reported in cluster headache.

    2 sources cited
    1. 7211. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
    2. 918. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.

    Carfilzomib

    Listed in the ADVERSE REACTIONS section of the FDA label for Carfilzomib. Read the label on DailyMed ›

  • Joint pain Additional detail

    Tyrosine

    “Orally, larger doses of tyrosine (150 mg/kg) can cause arthralgia, but this is uncommon.”

    Tyrosine · Natural Medicines adverse-effect record, reported in myasthenia gravis.

    1 source cited
    1. 7211. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.

    Carfilzomib

    Listed in the ADVERSE REACTIONS section of the FDA label for Carfilzomib. Read the label on DailyMed ›

  • Tiredness / Headache Additional detail

    Tyrosine

    “Orally, tyrosine seems to be well tolerated. No serious adverse effects have been documented; however, a thorough evaluation of safety outcomes has not been conducted.

    Most Common Adverse Effects:

    Orally: Fatigue, headache, heartburn, and nausea.”

    Tyrosine · Natural Medicines adverse-effect record, reported in cluster headache.

    Carfilzomib

    Listed in the ADVERSE REACTIONS section of the FDA label for Carfilzomib. Read the label on DailyMed ›

  • Diarrhea / Vomiting Additional detail

    Tyrosine

    “Orally, tyrosine can cause nausea and heartburn when taken at a dose of 150 mg/kg. Taking tyrosine 4 grams daily in combination with 5-hydroxytryptophan 800 mg and carbidopa 100 mg can cause diarrhea, nausea, and vomiting. These effects can be mitigated by lowering the dosage.”

    Tyrosine · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 7211. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
    2. 918. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.

    Carfilzomib

    Listed in the ADVERSE REACTIONS section of the FDA label for Carfilzomib. Read the label on DailyMed ›

  • Nausea Additional detail

    Tyrosine

    Recorded for Tyrosine in the same Natural Medicines adverse-effect record shown under Tiredness / Headache above.

    Carfilzomib

    Listed in the ADVERSE REACTIONS section of the FDA label for Carfilzomib. Read the label on DailyMed ›

Reported for Tyrosine but not commonly for Carfilzomib: drowsiness and heartburn.

Effects for Carfilzomib come from the ADVERSE REACTIONS section of its FDA label; effects for Tyrosine come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Tyrosine or Carfilzomib

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Tyrosine or Carfilzomib, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Carfilzomib

This page covers Tyrosine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Carfilzomib page lists 38 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Beer (major), Siberian Cocklebur (major), Wine (major), Ashwagandha (moderate) and Black Cohosh (moderate).

By severity: 3 major · 35 moderate.

From our pharmacist’s overview on the Carfilzomib page

“Every supplement on this page shares a single concern with carfilzomib (Kyprolis): extra strain on the liver. Carfilzomib is an IV chemotherapy for multiple myeloma, and that treatment is demanding enough without an herb quietly injuring the organ that has to keep pace.”

Reviewed by 2 · Jul 18, 2026

Open the Carfilzomib interaction page

One more smart check

Taking Tyrosine as Part of a Dietary Supplement Product? Check It for Interactions

We hold 4,448 real supplement products containing Tyrosine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Tyrosine. Even though Tyrosine itself has no known interaction with Carfilzomib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Tyrosine and Carfilzomib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Tyrosine
Top 5%

#44 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Carfilzomib
Top half

#1,120 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tyrosine reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Tyrosine and Carfilzomib records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Tyrosine

What is Tyrosine?

  • Mental focus and alertness
  • Coping with stress
  • Fatigue and sleep loss
  • Mood support
  • Athletic and cognitive performance

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performance during short-term stress, sleep loss, or cold, but the evidence is mixed and it is not proven for everyday focus or mood. It is generally well tolerated in healthy adults, but check with your pharmacist or doctor before using it, especially during pregnancy or if you have a thyroid condition.

Amino acid (made in the body or produced by fermentation/synthesis for supplements) · Capsules, tablets, powder, and as L-tyrosine or N-acetyl-L-tyrosine

An interaction check asks whether these two react with each other — it does not ask whether Tyrosine is a good idea for someone in your situation. Here is what our Tyrosine record says about it on its own.

Tyrosine: dosing

There is no official standardized dose for tyrosine, and the amounts used in studies vary widely. Because of this, the best approach is to follow the directions on the product label and not exceed them.Doses are often based on body weight in research settings and taken a short time before a stressful or demanding task.

From our Tyrosine monograph — the full record covers uses, side effects and every documented interaction.

Read the full Tyrosine monograph & all interactions
Medication

About Carfilzomib Injection

What Is Carfilzomib Injection Used For?

Brand name: Kyprolis

Kyprolis is used for adults with relapsed or refractory multiple myeloma. This is a blood cancer that has come back or has not responded to earlier treatment.

Kyprolis is used in combination with other medicines for people who have had one to three prior lines of therapy. It is also used alone for people who have had one or more prior lines of therapy.

See full Carfilzomib Injection drug information
Keep checking

Other Drugs & Tyrosine

Browse every other medication we’ve checked against Tyrosine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
21Moderate
0Minor
2,808No known interaction
21 Moderate 2,808 No interaction
Moderate

21 interactions

No interaction 2,808 drugs checked — show the list

We also checked Tyrosine against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,808 medications checked with no known interaction — see the full Tyrosine list.

See the full Tyrosine interactions page
See every supplement checked against Carfilzomib, ranked by severity
Evidence & sources

Tyrosine References

The 4 references that drive our Tyrosine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  2. DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
  3. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
  4. van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Tyrosine and Carfilzomib Together: Common Questions

Is it safe to take Tyrosine with Carfilzomib?
We do not list a known interaction between Tyrosine and Carfilzomib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Tyrosine and Carfilzomib have any of the same side effects?
Yes — our sources link each of them separately to 7 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Tyrosine and Carfilzomib combination checked?
Interactions in our licensed database are recorded against drug classes. Carfilzomib is filed under 1 classification, and Tyrosine has documented interactions with 2 drug classes — none of Carfilzomib's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Tyrosine interact with any other medications?
Yes. Tyrosine has 21 documented drug interactions in our database — Carfilzomib is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Carfilzomib interact with any supplements?
Yes. Carfilzomib has documented interactions with 38 supplements in our database — Tyrosine is not one of them. The Carfilzomib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Tyrosine monograph Uses, safety profile, and every drug interaction in one place Carfilzomib Injection drug information The full plain-English guide to this medication Carfilzomib supplement interactions Every supplement checked against Carfilzomib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Carfilzomib and Tyrosine?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.