Drug & supplement interaction

Tyrosine + Rivastigmine

Rivastigmine brand names: Exelon, Exelon Patch.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Tyrosine and Rivastigmine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Tyrosine and Rivastigmine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Rivastigmine and Tyrosine in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Tyrosine safety at a glance

Tyrosine overall Use caution Generally well tolerated in healthy adults, but talk to a healthcare provider before regular use.
Pregnancy Use caution Not enough safety data; avoid supplemental doses unless a doctor advises otherwise.
Breastfeeding Use caution Not enough safety data, so caution is advised while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Rivastigmine and Tyrosine? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Rivastigmine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Rivastigmine is filed under 3 classifications — acetylcholinesterase (ache) inhibitors, cholinergic drugs, oral drugs. Tyrosine has documented interactions with 2 drug classes — the most serious being levodopa (moderate) and thyroid hormone (moderate) — and none of Rivastigmine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Tyrosine Does Interact With Other Medications

Tyrosine has 21 moderate known drug interactions in our database — Rivastigmine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 21 No known interaction 2,809 (incl. Rivastigmine)
Taking anything else?

Check Another of Your Medications Against Tyrosine

Covers the 2,830 medications we’ve checked against Tyrosine. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Tyrosine and Rivastigmine May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Anxiety or restlessness Additional detail

    Tyrosine

    “Orally, larger doses of tyrosine (150 mg/kg) can cause headache and fatigue. Taking a combination of tyrosine 4 grams, 5-hydroxytryptophan 800 mg, and carbidopa 100 mg can cause drowsiness and agitation. These effects can be mitigated by lowering the dosage.”

    Tyrosine · Natural Medicines adverse-effect record, reported in cluster headache.

    2 sources cited
    1. 7211. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
    2. 918. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.

    Rivastigmine

    Listed in the ADVERSE REACTIONS section of the FDA label for Rivastigmine. Read the label on DailyMed ›

  • Tiredness / Headache Additional detail

    Tyrosine

    “Orally, tyrosine seems to be well tolerated. No serious adverse effects have been documented; however, a thorough evaluation of safety outcomes has not been conducted.

    Most Common Adverse Effects:

    Orally: Fatigue, headache, heartburn, and nausea.”

    Tyrosine · Natural Medicines adverse-effect record, reported in cluster headache.

    Rivastigmine

    Listed in the ADVERSE REACTIONS section of the FDA label for Rivastigmine. Read the label on DailyMed ›

  • Diarrhea / Vomiting Additional detail

    Tyrosine

    “Orally, tyrosine can cause nausea and heartburn when taken at a dose of 150 mg/kg. Taking tyrosine 4 grams daily in combination with 5-hydroxytryptophan 800 mg and carbidopa 100 mg can cause diarrhea, nausea, and vomiting. These effects can be mitigated by lowering the dosage.”

    Tyrosine · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 7211. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
    2. 918. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.

    Rivastigmine

    Listed in the ADVERSE REACTIONS section of the FDA label for Rivastigmine. Read the label on DailyMed ›

  • Nausea Additional detail

    Tyrosine

    Recorded for Tyrosine in the same Natural Medicines adverse-effect record shown under Tiredness / Headache above.

    Rivastigmine

    Listed in the ADVERSE REACTIONS section of the FDA label for Rivastigmine. Read the label on DailyMed ›

Reported for Tyrosine but not commonly for Rivastigmine: drowsiness, joint pain and heartburn.

Effects for Rivastigmine come from the ADVERSE REACTIONS section of its FDA label; effects for Tyrosine come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Overlapping uses

What Rivastigmine Is Prescribed For, and What Tyrosine Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Rivastigmine is a prescription medicine with approved uses on its FDA label. Tyrosine is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Rivastigmine is prescribed for: Rivastigmine treats dementia — the memory loss, confusion, and thinking problems that come with certain brain diseases. The specific conditions it's approved for depend on the form. Rivastigmine Tartrate capsules are approved for mild-to-moderate dementia caused by Alzheimer's disease or Parkinson's disease. The skin patch forms — including Exelon, Rivastigmine, and Rivastigmine Transdermal System — are approved for mild, moderate, and severe Alzheimer's disease dementia, as well as mild-to-moderate dementia associated with Parkinson's disease.

Tyrosine has been studied for:

  • Memory Natural Medicines rates the evidence for Tyrosine: Possibly Effective Read what the research shows

    Tyrosine for memory

    Taking tyrosine orally seems to improve memory in patients exposed to stressors such as cold or those having to complete multiple tasks at once.

  • Dementia studied, not established Tyrosine has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Tyrosine for dementia

    Oral tyrosine has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Rivastigmine on your own; if you are taking Tyrosine for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Tyrosine or Rivastigmine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Tyrosine or Rivastigmine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Rivastigmine

This page covers Tyrosine only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Rivastigmine page lists 39 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Arenaria Rubra (moderate), Bacopa (moderate), Bael (moderate) and Betel Nut (moderate).

By severity: 1 major · 28 moderate · 10 minor.

From our pharmacist’s overview on the Rivastigmine page

“Rivastigmine (Exelon, Exelon Patch) raises acetylcholine in the brain to treat Alzheimer's and Parkinson's dementia, and most of the 39 supplements and herbs on this page pull on that same lever, so this is a list to treat with real care. Twenty-one entries, huperzine A among them, act like weaker versions of the drug and can stack its…”

Reviewed by 2 · Jul 18, 2026

Open the Rivastigmine interaction page

One more smart check

Taking Tyrosine as Part of a Dietary Supplement Product? Check It for Interactions

We hold 4,448 real supplement products containing Tyrosine, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Tyrosine. Even though Tyrosine itself has no known interaction with Rivastigmine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Tyrosine and Rivastigmine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Tyrosine
Top 5%

#41 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Rivastigmine
Top half

#1,387 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Tyrosine reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Tyrosine and Rivastigmine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Tyrosine

What is Tyrosine?

  • Mental focus and alertness
  • Coping with stress
  • Fatigue and sleep loss
  • Mood support
  • Athletic and cognitive performance

L-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performance during short-term stress, sleep loss, or cold, but the evidence is mixed and it is not proven for everyday focus or mood. It is generally well tolerated in healthy adults, but check with your pharmacist or doctor before using it, especially during pregnancy or if you have a thyroid condition.

Amino acid (made in the body or produced by fermentation/synthesis for supplements) · Capsules, tablets, powder, and as L-tyrosine or N-acetyl-L-tyrosine

An interaction check asks whether these two react with each other — it does not ask whether Tyrosine is a good idea for someone in your situation. Here is what our Tyrosine record says about it on its own.

Tyrosine: dosing

There is no official standardized dose for tyrosine, and the amounts used in studies vary widely. Because of this, the best approach is to follow the directions on the product label and not exceed them.Doses are often based on body weight in research settings and taken a short time before a stressful or demanding task.

From our Tyrosine monograph — the full record covers uses, side effects and every documented interaction.

Read the full Tyrosine monograph & all interactions
Medication

About Rivastigmine

What Is Rivastigmine Used For?

Brand names: Exelon, Exelon Patch

Rivastigmine treats dementia — the memory loss, confusion, and thinking problems that come with certain brain diseases. The specific conditions it's approved for depend on the form.

Rivastigmine Tartrate capsules are approved for mild-to-moderate dementia caused by Alzheimer's disease or Parkinson's disease. The skin patch forms — including Exelon, Rivastigmine, and Rivastigmine Transdermal System — are approved for mild, moderate, and severe Alzheimer's disease dementia, as well as mild-to-moderate dementia associated with Parkinson's disease.

See full Rivastigmine drug information
Keep checking

Other Drugs & Tyrosine

Browse every other medication we’ve checked against Tyrosine — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
21Moderate
0Minor
2,808No known interaction
21 Moderate 2,808 No interaction
Moderate

21 interactions

No interaction 2,808 drugs checked — show the list

We also checked Tyrosine against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,808 medications checked with no known interaction — see the full Tyrosine list.

See the full Tyrosine interactions page
See every supplement checked against Rivastigmine, ranked by severity
Evidence & sources

Tyrosine References

The 4 references that drive our Tyrosine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  2. DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
  3. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
  4. van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Tyrosine and Rivastigmine Together: Common Questions

Is it safe to take Tyrosine with Rivastigmine?
We do not list a known interaction between Tyrosine and Rivastigmine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Tyrosine and Rivastigmine have any of the same side effects?
Yes — our sources link each of them separately to 6 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Tyrosine and Rivastigmine used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Tyrosine in each. That is a conversation for your prescriber, especially if Rivastigmine is being adjusted to a target.
How was the Tyrosine and Rivastigmine combination checked?
Interactions in our licensed database are recorded against drug classes. Rivastigmine is filed under 3 classifications, and Tyrosine has documented interactions with 2 drug classes — none of Rivastigmine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Tyrosine interact with any other medications?
Yes. Tyrosine has 21 documented drug interactions in our database — Rivastigmine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Rivastigmine interact with any supplements?
Yes. Rivastigmine has documented interactions with 39 supplements in our database — Tyrosine is not one of them. The Rivastigmine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Tyrosine monograph Uses, safety profile, and every drug interaction in one place Rivastigmine drug information The full plain-English guide to this medication Rivastigmine supplement interactions Every supplement checked against Rivastigmine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Rivastigmine and Tyrosine?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.