Urine Therapy + Norgestrel
Norgestrel brand names: Ovrette, Orval 21.
We found no known interaction between Urine Therapy and Norgestrel in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Urine Therapy and Norgestrel
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Norgestrel and Urine Therapy in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Urine Therapy at all — not against Norgestrel, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Urine Therapy safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Norgestrel
This page covers Urine Therapy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Norgestrel page lists 188 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).
By severity: 6 major · 140 moderate · 42 minor.
From our pharmacist’s overview on the Norgestrel page
“Norgestrel (Ovrette) is a progestin-only birth control pill, so the biggest danger on this page is not a strange side effect but a pill that quietly stops working. That risk makes this a page for genuine vigilance.”
Reviewed by 2 · Jul 18, 2026
Where Urine Therapy and Norgestrel Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,352 of 1,452 supplements looked up here in the last 7 days
#1,502 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Urine Therapy is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Urine Therapy reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Urine Therapy and Norgestrel records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Urine Therapy
What is Urine Therapy?
- General wellness and detox beliefs
- Skin conditions
- Wound or rash care
- Allergies
- Cancer (alternative use)
- Infections
Urine therapy is a practice of drinking or applying one's own urine, promoted in some traditional and alternative health circles. There is no reliable scientific evidence that it treats or prevents any disease, and drinking urine can cause harm. We do not recommend it.
Human urine (one's own) · Drinking fresh urine, skin application, gargling, eye or ear drops
An interaction check asks whether these two react with each other — it does not ask whether Urine Therapy is a good idea for someone in your situation. Here is what our Urine Therapy record says about it on its own.
Urine Therapy: dosing
There is no established or safe dose for urine therapy because it is not a recognized medical treatment. There are safer, evidence-based options for nearly every condition people use it for.
From our Urine Therapy monograph — the full record covers uses, side effects and every documented interaction.
About Progestin-Only (norethindrone) Oral Contraceptives
What Is Progestin-Only (norethindrone) Oral Contraceptives Used For?
Brand names: Ovrette, Orval 21
Norethindrone progestin-only pills — sometimes called the "mini-pill" — are used solely to prevent pregnancy. They do not contain estrogen, which makes them an option for women who cannot or prefer not to use estrogen-containing contraceptives.
When taken perfectly (same time every day, no missed pills), fewer than 1 in 100 women will become pregnant in the first year. With typical use, that number rises to about 9 in 100 — mostly because of late or skipped pills. Consistency is everything with this method.
Most-Reported Side Effects for Norgestrel
From FAERS, the FDA’s public side-effect reporting system (2,254 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Urine Therapy
Browse every other medication we’ve checked against Urine Therapy — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Urine Therapy against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Warfarin ›
- Methylphenidate ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Aspirin ›
- Abemaciclib ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tadalafil ›
- Tirzepatide ›
- Methamphetamine ›
- Ibuprofen ›
- Valacyclovir ›
- Warfarin Sodium ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Clonazepam ›
- Quetiapine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Duloxetine ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Urine Therapy list.
Urine Therapy References
The 2 sources that drive our Urine Therapy monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Urine Therapy is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Norgestrel Is Linked to Lower Levels of 2 Nutrients
Natural Medicines records Norgestrel as a medicine that can lower these. This is not an interaction with Urine Therapy — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Norgestrel nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Urine Therapy and Norgestrel Together: Common Questions
Is it safe to take Urine Therapy with Norgestrel?
Does Norgestrel interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Norgestrel and Urine Therapy?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.