Drug & supplement interaction

Veronica + Propoxyphene

Propoxyphene brand names: Darvon, Prophene-65, Margesic, Davon.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Veronica and Propoxyphene in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Veronica and Propoxyphene

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Propoxyphene and Veronica in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Veronica at all — not against Propoxyphene, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Veronica safety at a glance

Veronica overall Use caution Long traditional use but very limited modern safety data, so use cautiously.
Pregnancy Avoid Not enough safety information; avoid during pregnancy.
Breastfeeding Avoid Not enough safety information; avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Propoxyphene and Veronica? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Propoxyphene’s Own FDA Label Lists

This is not an interaction — none of it involves Veronica. These are the most notable effects listed in the ADVERSE REACTIONS section of Propoxyphene’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Trouble swallowing Worth acting on
  • High blood sugar Worth acting on
  • Fainting Worth acting on
  • Confusion Worth acting on
  • A severe skin reaction Worth acting on
  • Seizures Worth acting on
  • Low mood Worth acting on
  • A low platelet count Worth acting on
  • Kidney problems Worth acting on
  • Shortness of breath Worth acting on

Showing the 10 most notable of 36 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Propoxyphene. Read the label on DailyMed › Veronica’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Veronica side to compare — that is a limit of the record, not a statement that Veronica has no side effects.

Everything else you take

See Every Supplement That Interacts With Propoxyphene

This page covers Veronica only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Propoxyphene page lists 172 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 8 major · 141 moderate · 23 minor.

From our pharmacist’s overview on the Propoxyphene page

“Propoxyphene (Darvon) is an opioid painkiller, and the biggest hazard among the 172 supplement interactions on file is anything else that slows the brain and breathing. Seventy-eight of these ingredients pile on that sedation, alcohol and kava among the worst rated, and with an opioid the combination can push breathing dangerously low.”

Reviewed by 2 · Jul 18, 2026

Open the Propoxyphene interaction page

One more smart check

Taking Veronica as Part of a Dietary Supplement Product? Check It for Interactions

We hold 10 real supplement products containing Veronica, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Veronica. Even though Veronica itself has no known interaction with Propoxyphene, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Veronica and Propoxyphene Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Veronica
Steady interest

#1,012 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Propoxyphene
Top 5%

#73 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Veronica is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Veronica reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Veronica and Propoxyphene records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Veronica

What is Veronica?

Veronica
  • Coughs and respiratory complaints
  • Digestive upset and appetite stimulation
  • Gout, arthritis, and rheumatic complaints
  • Kidney and urinary tract conditions
  • Mouth and throat inflammation (topical)

Veronica (speedwell) is a traditional European herb used mainly for coughs, digestive complaints, and joint problems, but there is very little modern scientific evidence to show it actually works for any of these. It is generally considered mild, but its safety has not been well studied, so check with a pharmacist or doctor before using it — and avoid it during pregnancy and breastfeeding.

Veronica officinalis · Plantaginaceae · Above-ground (aerial) parts — the flowering herb, including leaves and stems · Tea (infusion), tincture, dried herb, and topical rinses or gargles

An interaction check asks whether these two react with each other — it does not ask whether Veronica is a good idea for someone in your situation. Here is what our Veronica record says about it on its own.

Veronica: dosing

There is no standardized or scientifically established dose for Veronica. Traditional use has mostly involved a tea made from the dried herb or a tincture, but exact safe and effective amounts have not been determined by research.If you use a commercial product, follow the directions on the label and do not exceed the recommended amount.

From our Veronica monograph — the full record covers uses, side effects and every documented interaction.

Read the full Veronica monograph & all interactions
Medication

About Acetaminophen, Butalbital, and Caffeine

What Is Acetaminophen, Butalbital, and Caffeine Used For?

Brand names: Darvon, Prophene-65, Margesic, Davon

This three-ingredient combination — butalbital, acetaminophen, and caffeine — is used to relieve the symptoms of tension headache (also called muscle contraction headache). All supported products, including tablets, capsules, and oral solution, share this same approved use.

It is worth knowing that evidence for using this combination to treat repeated, frequent tension headaches over time is limited. Because butalbital can be habit-forming, extended or repeated use is not recommended.

See full Acetaminophen, Butalbital, and Caffeine drug information
Keep checking

Other Drugs & Veronica

Browse every other medication we’ve checked against Veronica — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Veronica References

The 1 sources that drive our Veronica monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Veronica is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH National Center for Complementary and Integrative Health Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Veronica and Propoxyphene Together: Common Questions

Is it safe to take Veronica with Propoxyphene?
We do not list a known interaction between Veronica and Propoxyphene. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Propoxyphene interact with any supplements?
Yes. Propoxyphene has documented interactions with 172 supplements in our database — Veronica is not one of them. The Propoxyphene interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Propoxyphene and Veronica?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.