Drug & supplement interaction

Vitamin A + Palivizumab

Palivizumab brand name: Synagis.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Vitamin A and Palivizumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Vitamin A and Palivizumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Palivizumab and Vitamin A in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Vitamin A safety at a glance

Vitamin A overall Use caution Generally safe at recommended amounts, but high doses can be toxic because it builds up in the body.
Pregnancy Likely Safe When used orally or intramuscularly and appropriately. Vitamin A, as pre-formed vitamin A (retinol or retinyl ester), is safe during pregnancy and lactation whe... Read the full pregnancy detail
Breastfeeding Likely Safe When used orally or intramuscularly and appropriately. Vitamin A, as pre-formed vitamin A (retinol or retinyl ester), is safe during pregnancy and lactation whe... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Palivizumab and Vitamin A? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Palivizumab

Interactions in our licensed database are recorded against drug classes, not just single drug names. Palivizumab is filed under a single classification — immunosuppressants. Vitamin A has documented interactions with 4 drug classes — the most serious being retinoids (major), hepatotoxic drugs (moderate) and tetracycline antibiotics (moderate) — and none of Palivizumab’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Vitamin A Does Interact With Other Medications

Vitamin A has 9 major, 378 moderate known drug interactions in our database — Palivizumab isn’t one of them. If you take anything else, check it against the full list below.

Major 9 Moderate 378 No known interaction 2,443 (incl. Palivizumab)
Taking anything else?

Check Another of Your Medications Against Vitamin A

Covers the 2,830 medications we’ve checked against Vitamin A. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Vitamin A and Palivizumab May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • A low platelet count Worth acting on Additional detail

    Vitamin A

    “Hypervitaminosis A can cause spider angiomas, anemia, leukopenia, leukocytosis, and thrombocytopenia (15,95051).”

    Vitamin A · Natural Medicines adverse-effect record, reported in anemia.

    2 sources cited
    1. 15. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
    2. 95051. Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102(6):556-8. PubMed

    Palivizumab

    Listed in the ADVERSE REACTIONS section of the FDA label for Palivizumab. Read the label on DailyMed ›

  • Fever Additional detail

    Vitamin A

    “Chronic use of large amounts of vitamin A (>25,000 IU daily for more than 6 years or 100,000 IU daily for more than 6 months) can cause symptoms of vitamin A toxicity including mild fever and excessive sweating. High intakes of vitamin A may result in a failure to gain weight normally in children and weight loss in adults (15).”

    Vitamin A · Natural Medicines adverse-effect record, reported in obesity.

    2 sources cited
    1. 7135. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
    2. 15. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.

    Palivizumab

    Listed in the ADVERSE REACTIONS section of the FDA label for Palivizumab. Read the label on DailyMed ›

  • A skin rash Additional detail

    Vitamin A

    “Chronic oral use of large amounts of vitamin A causes symptoms of vitamin A toxicity including dry skin and lips; cracking, scaling, and itchy skin; skin redness and rash; hyperpigmentation; shiny skin, and massive skin peeling. Hypervitaminosis A can cause brittle nails, cheilitis, gingivitis, and hair loss (15,95051).”

    Vitamin A · Natural Medicines adverse-effect record, reported in alopecia.

    3 sources cited
    1. 7135. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
    2. 95051. Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102(6):556-8. PubMed
    3. 15. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.

    Palivizumab

    Listed in the ADVERSE REACTIONS section of the FDA label for Palivizumab. Read the label on DailyMed ›

Reported for Vitamin A but not commonly for Palivizumab: liver problems, stomach upset, sweating and stomach pain.

Effects for Palivizumab come from the ADVERSE REACTIONS section of its FDA label; effects for Vitamin A come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Vitamin A in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally or intramuscularly and appropriately. Vitamin A, as pre-formed vitamin A (retinol or retinyl ester), is safe during pregnancy and lactation when used in doses less than 10,000 IU (3000 mcg) per day in adults 19 years of age and older and 2800 mcg daily in those 14-18 years of age. Vitamin A is available in two different forms: pre-formed vitamin A (retinol or retinyl ester) and provitamin A (carotenoids). The safety concerns associated with high vitamin A intake occur with pre-formed vitamin A only. Some supplements contain vitamin A in both pre-formed and provitamin A forms. For these supplements, the amount of pre-formed vitamin A should be used as the reference amount to determine safety.

Pregnancy And Lactation Possibly Unsafe

When used orally or intramuscularly in excessive doses. Daily intake of greater than 10,000 IU (3000 mcg) can cause fetal malformations. Excessive dietary intake of vitamin A has also been associated with teratogenicity. The first trimester of pregnancy seems to be the critical period for susceptibility to vitamin A-associated birth defects such as craniofacial abnormalities and abnormalities of the central nervous system. Pregnant patients should monitor their intake of pre-formed vitamin A (retinol or retinyl ester). This form of vitamin A is found in several foods including animal products, particularly fish and animal liver, some fortified breakfast cereals, and dietary supplements.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Palivizumab Is Prescribed For, and What Vitamin A Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Palivizumab is a prescription medicine with approved uses on its FDA label. Vitamin A is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Palivizumab is prescribed for: Synagis (palivizumab) is used to prevent serious lower respiratory tract disease caused by RSV — not to treat an infection that has already started. It is given to high-risk babies and young children before and during RSV season. Synagis is approved for infants born at 35 weeks gestation or earlier who are 6 months old or younger at the start of RSV season; children up to 24 months old with bronchopulmonary dysplasia (BPD, a chronic lung condition) who needed medical treatment in the past 6 months; and children up to 24 months old with hemodynamically significant congenital heart disease (a heart defect that affects blood flow).

Vitamin A has been studied for:

  • Bronchopulmonary dysplasia Natural Medicines rates the evidence for Vitamin A: Possibly Effective Read what the research shows

    Vitamin A for bronchopulmonary dysplasia

    Intramuscular vitamin A may reduce the risk of bronchopulmonary dysplasia (BPD) in very low birth weight infants when given at a dose of 5000 IU three times weekly for 28 days. Lower doses do not seem to be effective. It is unclear if enteral vitamin A is beneficial for BPD.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Palivizumab on your own; if you are taking Vitamin A for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Vitamin A or Palivizumab

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Vitamin A or Palivizumab, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Palivizumab

This page covers Vitamin A only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Palivizumab page lists 53 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Active Hexose Correlated Compound (ahcc) (moderate), Alfalfa (moderate), American Ginseng (moderate), Andrographis (moderate) and Ashwagandha (moderate).

By severity: 52 moderate · 1 minor.

From our pharmacist’s overview on the Palivizumab page

“Everything on this list for palivizumab (Synagis), the antibody injection given monthly to shield premature and other high-risk infants from RSV, points in one direction. These are supplements that stimulate the immune system, and stimulating the immune system could in theory work against a medicine that acts on it.”

Reviewed by 2 · Jul 18, 2026

Open the Palivizumab interaction page

One more smart check

Taking Vitamin A as Part of a Dietary Supplement Product? Check It for Interactions

We hold 19,215 real supplement products containing Vitamin A, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Vitamin A. Even though Vitamin A itself has no known interaction with Palivizumab, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Vitamin A and Palivizumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Vitamin A
Top 1%

#11 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Palivizumab
Steady interest

#1,770 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Vitamin A reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Vitamin A and Palivizumab records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Vitamin A

What is Vitamin A?

  • Eye and vision health
  • Skin health and acne
  • Immune support
  • Correcting vitamin A deficiency
  • Childhood growth and development

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplements are mainly useful for correcting a true deficiency. Because vitamin A is fat-soluble and can build up to harmful levels, more is not better, and high doses are especially risky in pregnancy.

Capsules, softgels, tablets, liquid drops, multivitamins; also found in foods

An interaction check asks whether these two react with each other — it does not ask whether Vitamin A is a good idea for someone in your situation. Here is what our Vitamin A record says about it on its own.

Vitamin A: dosing

Vitamin A needs are usually described in micrograms of retinol activity equivalents (mcg RAE) or sometimes older International Units (IU). Because of the risk of buildup, this is one supplement where taking extra is not helpful and can be harmful.There is no single "best" supplement dose for most people, and many do not need a separate vitamin A supplement at all.

From our Vitamin A monograph — the full record covers uses, side effects and every documented interaction.

Read the full Vitamin A monograph & all interactions
Medication

About Palivizumab Injection

What Is Palivizumab Injection Used For?

Brand name: Synagis

Synagis (palivizumab) is used to prevent serious lower respiratory tract disease caused by RSV — not to treat an infection that has already started. It is given to high-risk babies and young children before and during RSV season.

Synagis is approved for infants born at 35 weeks gestation or earlier who are 6 months old or younger at the start of RSV season; children up to 24 months old with bronchopulmonary dysplasia (BPD, a chronic lung condition) who needed medical treatment in the past 6 months; and children up to 24 months old with hemodynamically significant congenital heart disease (a heart defect that affects blood flow).

See full Palivizumab Injection drug information
Keep checking

Other Drugs & Vitamin A

Browse every other medication we’ve checked against Vitamin A — both the ones with a known interaction and the ones without. Select any drug for the full detail.

9Major
378Moderate
0Minor
2,442No known interaction
9 Major 378 Moderate 2,442 No interaction
Major

9 interactions

Moderate

378 interactions

Showing 60 of 378 moderate interactions — see all 378 on the Vitamin A page.

No interaction 2,442 drugs checked — show the list

We also checked Vitamin A against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,442 medications checked with no known interaction — see the full Vitamin A list.

See the full Vitamin A interactions page
See every supplement checked against Palivizumab, ranked by severity
Evidence & sources

Vitamin A References

The 31 references that drive our Vitamin A monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Griffiths JK. The vitamin A paradox. J Pediatr 2000;137:604-7.. PubMed
  3. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed. New York, NY: McGraw-Hill, 1996.
  4. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  5. FDA Talk Paper. Vitamin A and birth defects (T95-56). Food and Drug Administration, U.S. Department of Health and Human Services, Rockville, MD. October 6, 1995.
  6. Russell RM. The vitamin A spectrum: from deficiency to toxicity. Am J Clin Nutr 2000;71:878-84. PubMed
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54. PubMed
  9. Melhus H, Michaelsson K, Kindmark A, et al. Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture. Ann Intern Med 1998;129:770-8. PubMed
  10. Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.. PubMed
  11. Botterweck AA, van den Brandt PA, Goldbohm RA. Vitamins, carotenoids, dietary fiber, and the risk of gastric carcinoma: results from a prospective study after 6.3 years of follow-up. Cancer 2000;88:737-48.. DOI
  12. Meyskens FL Jr, Graham V, Chvapil M, et al. A phase I trial of beta-all-trans-retinoic acid delivered via a collagen sponge and a cervical cap for mild or moderate intraepithelial cervical neoplasia. J Natl Cancer Inst 1983;71:921-5..
  13. Hathcock JN, Hattan DG, Jenkins MY, et al. Evaluation of vitamin A toxicity. Am J Clin Nutr 1990;52:183-202.. PubMed
  14. Walters BN, Gubbay SS. Tetracycline and benign intracranial hypertension: report of five cases. Br Med J 1981;282:19-20.. PubMed
  15. Pearson MG, Littlewood SM, Bowden AN. Tetracycline and benign intracranial hypertension (letter). Br Med J 1981;282:568-9.. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Vitamin A and Palivizumab Together: Common Questions

Is it safe to take Vitamin A with Palivizumab?
We do not list a known interaction between Vitamin A and Palivizumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Vitamin A and Palivizumab have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Vitamin A and Palivizumab used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Vitamin A in each. That is a conversation for your prescriber, especially if Palivizumab is being adjusted to a target.
How was the Vitamin A and Palivizumab combination checked?
Interactions in our licensed database are recorded against drug classes. Palivizumab is filed under 1 classification, and Vitamin A has documented interactions with 4 drug classes — none of Palivizumab's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Vitamin A interact with any other medications?
Yes. Vitamin A has 387 documented drug interactions in our database — Palivizumab is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Palivizumab interact with any supplements?
Yes. Palivizumab has documented interactions with 53 supplements in our database — Vitamin A is not one of them. The Palivizumab interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Vitamin A monograph Uses, safety profile, and every drug interaction in one place Palivizumab Injection drug information The full plain-English guide to this medication Palivizumab supplement interactions Every supplement checked against Palivizumab, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 31 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Palivizumab and Vitamin A?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.