Drug & supplement interaction

Wasabi + Epoetin Beta

Epoetin Beta brand names: Recormon, Mircera.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Wasabi and Epoetin Beta in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Wasabi and Epoetin Beta

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Epoetin Beta and Wasabi in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Wasabi safety at a glance

Wasabi overall Use caution Generally safe as a food, but supplement-strength doses are not well studied in people.
Pregnancy Use caution Food amounts are likely fine, but avoid concentrated supplements due to a lack of safety data.
Breastfeeding Use caution Food amounts are likely fine, but supplement doses have not been studied, so caution is best.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Epoetin Beta and Wasabi? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Epoetin Beta

Interactions in our licensed database are recorded against drug classes, not just single drug names. Epoetin Beta is filed under 2 classifications — seizure threshold lowering drugs, oral drugs. Wasabi has documented interactions with 1 drug class — the most serious being anticoagulant/antiplatelet drugs (moderate) — and none of Epoetin Beta’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Wasabi Does Interact With Other Medications

Wasabi has 122 moderate known drug interactions in our database — Epoetin Beta isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Wasabi

Covers the 2,830 medications we’ve checked against Wasabi. Pick one to open its full report.

What to actually watch for

What Wasabi Itself Has Been Linked To

This is not an interaction — nothing below involves Epoetin Beta. It is the side-effect record for Wasabi on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Wasabi, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Kidney problems Worth acting on Additional detail

    “A small clinical study in adults taking oral wasabi extract 1000 mg once daily for 4 weeks has found 2 cases of proteinuria.”

    Wasabi · Natural Medicines adverse-effect record, reported in myasthenia gravis.

    1 source cited
    1. 112846. Nakajima R, Kanou M, Tokushima M, Iwama Y, Yamana K. Oral administration of 6-methylsulfinylhexyl isothiocyanate extracted from wasabi is safe and improves the fatigue and sleep of healthy volunteers. Biopsychosoc Med 2023;17(1):30. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Wasabi — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Epoetin Beta’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Epoetin Beta column appears here.

Overlapping uses

What Epoetin Beta Is Prescribed For, and What Wasabi Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Epoetin Beta is a prescription medicine with approved uses on its FDA label. Wasabi is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Epoetin Beta is prescribed for: Mircera is used to treat anemia associated with chronic kidney disease (CKD) in adult patients, whether or not they are on dialysis. It is also approved for pediatric patients aged 3 months to 17 years who are on dialysis or not on dialysis, but only when they are converting from another ESA after their hemoglobin level has already been stabilized. Mircera is not indicated for anemia caused by cancer chemotherapy, and it is not a substitute for red blood cell (RBC) transfusions when anemia needs to be corrected immediately. It has not been shown to improve symptoms, fatigue, or quality of life.

Wasabi has been studied for:

  • Fatigue studied, not established Wasabi has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Wasabi for fatigue

    It is unclear if oral wasabi is beneficial for fatigue.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Epoetin Beta on your own; if you are taking Wasabi for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Epoetin Beta

This page covers Wasabi only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Epoetin Beta page lists 23 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Biofeedback (moderate), Coffee Charcoal (moderate), Dendrobium (moderate) and European Mandrake (moderate).

By severity: 1 major · 13 moderate · 9 minor.

From our pharmacist’s overview on the Epoetin Beta page

“Epoetin Beta (Recormon, Mircera) prompts the body to make more red blood cells, usually for anemia from kidney disease or chemotherapy, and its 23 supplement interactions warrant genuine care, starting with the single major one. Activated charcoal can cut exposure to many drugs regardless of how they are given, which could undercut a t…”

Reviewed by 2 · Jul 18, 2026

Open the Epoetin Beta interaction page

How much people look this up

Where Wasabi and Epoetin Beta Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Wasabi
Steady interest

#878 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Epoetin Beta
Steady interest

#2,710 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Wasabi reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Wasabi and Epoetin Beta records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Wasabi

What is Wasabi?

Wasabi
  • Flavoring for sushi and other foods
  • Antimicrobial support
  • Anti-inflammatory support
  • Antioxidant support
  • General immune support

Wasabi is best known as the pungent green condiment served with sushi, made from a Japanese plant in the cabbage family. Its natural compounds (isothiocyanates) show antimicrobial and antioxidant activity in lab studies, but there is very little human research to support taking it as a supplement. As a food it is generally safe; as a concentrated supplement, talk with your pharmacist or doctor first.

Eutrema japonicum · Brassicaceae · Rhizome (root stem), and sometimes the leaves and stalks · Fresh paste, dried powder, capsules, extracts, and as a culinary condiment

An interaction check asks whether these two react with each other — it does not ask whether Wasabi is a good idea for someone in your situation. Here is what our Wasabi record says about it on its own.

Wasabi: dosing

There is no established standard dose for wasabi as a supplement. Research has not identified a safe and effective amount for any specific health purpose.If you choose to use a wasabi product, follow the directions on the label and do not exceed the recommended amount.

From our Wasabi monograph — the full record covers uses, side effects and every documented interaction.

Read the full Wasabi monograph & all interactions
Medication

About Methoxy Polyethylene Glycol-Epoetin Beta Injection

What Is Methoxy Polyethylene Glycol-Epoetin Beta Injection Used For?

Brand names: Recormon, Mircera

Mircera is used to treat anemia associated with chronic kidney disease (CKD) in adult patients, whether or not they are on dialysis. It is also approved for pediatric patients aged 3 months to 17 years who are on dialysis or not on dialysis, but only when they are converting from another ESA after their hemoglobin level has already been stabilized.

Mircera is not indicated for anemia caused by cancer chemotherapy, and it is not a substitute for red blood cell (RBC) transfusions when anemia needs to be corrected immediately. It has not been shown to improve symptoms, fatigue, or quality of life.

See full Methoxy Polyethylene Glycol-Epoetin Beta Injection drug information
Keep checking

Other Drugs & Wasabi

Browse every other medication we’ve checked against Wasabi — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
122Moderate
0Minor
2,707No known interaction
Moderate

122 interactions

Showing 60 of 122 moderate interactions — see all 122 on the Wasabi page.

No interaction 2,707 drugs checked — show the list
Evidence & sources

Wasabi References

The 2 references that drive our Wasabi monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Morimitsu, Y., Hayashi, K., Nakagawa, Y., Fujii, H., Horio, F., Uchida, K., and Osawa, T. Antiplatelet and anticancer isothiocyanates in Japanese domestic horseradish, Wasabi. Mech Ageing Dev 2000;116(2-3):125-134. PubMed
  2. Nakajima R, Kanou M, Tokushima M, Iwama Y, Yamana K. Oral administration of 6-methylsulfinylhexyl isothiocyanate extracted from wasabi is safe and improves the fatigue and sleep of healthy volunteers. Biopsychosoc Med 2023;17(1):30. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Wasabi and Epoetin Beta Together: Common Questions

Is it safe to take Wasabi with Epoetin Beta?
We do not list a known interaction between Wasabi and Epoetin Beta. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Wasabi and Epoetin Beta used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Wasabi in each. That is a conversation for your prescriber, especially if Epoetin Beta is being adjusted to a target.
How was the Wasabi and Epoetin Beta combination checked?
Interactions in our licensed database are recorded against drug classes. Epoetin Beta is filed under 2 classifications, and Wasabi has documented interactions with 1 drug class — none of Epoetin Beta's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Wasabi interact with any other medications?
Yes. Wasabi has 122 documented drug interactions in our database — Epoetin Beta is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Epoetin Beta interact with any supplements?
Yes. Epoetin Beta has documented interactions with 23 supplements in our database — Wasabi is not one of them. The Epoetin Beta interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Epoetin Beta and Wasabi?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.