Drug & supplement interaction

Water Avens + Elotuzumab

Elotuzumab brand name: Empliciti.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Water Avens and Elotuzumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Water Avens and Elotuzumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Elotuzumab and Water Avens in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Water Avens at all — not against Elotuzumab, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Water Avens safety at a glance

Water Avens overall Not established Little modern safety data exists, so caution is advised.
Pregnancy Avoid Safety is not established, so avoid use during pregnancy.
Breastfeeding Avoid Safety is not established, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Elotuzumab and Water Avens? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Elotuzumab’s Own FDA Label Lists

This is not an interaction — none of it involves Water Avens. These are the most notable effects listed in the ADVERSE REACTIONS section of Elotuzumab’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 9 of them are worth acting on rather than waiting out — marked below.

  • High potassium Worth acting on
  • Blood clots Worth acting on
  • High blood sugar Worth acting on
  • A low platelet count Worth acting on
  • Kidney problems Worth acting on
  • Anemia Worth acting on
  • A low white blood cell count Worth acting on
  • Liver problems Worth acting on
  • A higher chance of infection Worth acting on
  • Weight loss

Showing the 10 most notable of 20 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Elotuzumab. Read the label on DailyMed › Water Avens’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Water Avens side to compare — that is a limit of the record, not a statement that Water Avens has no side effects.

Everything else you take

See Every Supplement That Interacts With Elotuzumab

This page covers Water Avens only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Elotuzumab page lists 38 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Beer (major), Siberian Cocklebur (major), Wine (major), Ashwagandha (moderate) and Black Cohosh (moderate).

By severity: 3 major · 35 moderate.

From our pharmacist’s overview on the Elotuzumab page

“Elotuzumab (Empliciti) is an infusion for multiple myeloma, and every one of the 38 supplement interactions on file for it comes down to the same organ: the liver. Each ingredient here can stress or injure the liver on its own, and stacking that risk on top of cancer treatment deserves genuine care.”

Reviewed by 2 · Jul 18, 2026

Open the Elotuzumab interaction page

How much people look this up

Where Water Avens and Elotuzumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Water Avens
Steady interest

#917 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Elotuzumab
Top 5%

#67 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Water Avens is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Water Avens reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Water Avens and Elotuzumab records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Water Avens

What is Water Avens?

  • Diarrhea and digestive upset
  • Sore throat and mouth irritation
  • Mild fever
  • General tonic
  • Astringent for minor wounds

Water avens is a traditional herb whose root has been used as an astringent for diarrhea, sore throats, and digestive complaints. There is very little modern scientific research to confirm that it works or to define a safe dose, so use it cautiously and talk with a pharmacist or doctor first.

Geum rivale · Rosaceae · Root and rhizome (occasionally aerial parts) · Dried root, tea/decoction, tincture

An interaction check asks whether these two react with each other — it does not ask whether Water Avens is a good idea for someone in your situation. Here is what our Water Avens record says about it on its own.

Water Avens: dosing

There is no established or standardized dose for water avens. Traditional use involved teas (decoctions) of the dried root or tinctures, but reliable, research-based dosing is not available.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Water Avens monograph — the full record covers uses, side effects and every documented interaction.

Read the full Water Avens monograph & all interactions
Medication

About Elotuzumab Injection

What Is Elotuzumab Injection Used For?

Brand name: Empliciti

Empliciti is used to treat multiple myeloma (a cancer of plasma cells in the bone marrow) in adults who have already tried other treatments. It is always given as part of a combination regimen — never alone.

Empliciti combined with lenalidomide and dexamethasone is used in adults who have received one to three prior therapies. Empliciti combined with pomalidomide and dexamethasone is used in adults who have received at least two prior therapies, including lenalidomide and a proteasome inhibitor.

Most-Reported Side Effects for Elotuzumab

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Plasma cell myeloma 564 reports
Pneumonia 304 reports
Malignant neoplasm progression 254 reports
Fatigue 236 reports
Diarrhea 231 reports
See full Elotuzumab Injection drug information
Keep checking

Other Drugs & Water Avens

Browse every other medication we’ve checked against Water Avens — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Water Avens References

The 2 sources that drive our Water Avens monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Water Avens is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Herbs at a Glance — NIH National Center for Complementary and Integrative Health Source
  2. Herbs and Supplements — MedlinePlus (U.S. National Library of Medicine) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Water Avens and Elotuzumab Together: Common Questions

Is it safe to take Water Avens with Elotuzumab?
We do not list a known interaction between Water Avens and Elotuzumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Elotuzumab interact with any supplements?
Yes. Elotuzumab has documented interactions with 38 supplements in our database — Water Avens is not one of them. The Elotuzumab interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Elotuzumab and Water Avens?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.