Drug & supplement interaction

Water Avens + Maraviroc

Maraviroc brand names: Celsentri, Selzentry.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Water Avens and Maraviroc in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Water Avens and Maraviroc

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Maraviroc and Water Avens in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Water Avens at all — not against Maraviroc, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Water Avens safety at a glance

Water Avens overall Not established Little modern safety data exists, so caution is advised.

Pregnancy Avoid Safety is not established, so avoid use during pregnancy.

Breastfeeding Avoid Safety is not established, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Maraviroc and Water Avens? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

What to actually watch for

What Maraviroc’s Own FDA Label Lists

This is not an interaction — none of it involves Water Avens. These are the most notable effects listed in the ADVERSE REACTIONS section of Maraviroc’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 4 of them are worth acting on rather than waiting out — marked below.

Fainting Worth acting on
Liver problems Worth acting on
A higher chance of infection Worth acting on
An allergic reaction Worth acting on
Bloating or gas
A stuffy or runny nose
Anxiety or restlessness mentioned in 4.1% of FDA reports for Maraviroc
Cough
Low blood pressure
Fever

Showing the 10 most notable of 18 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Maraviroc. Read the label on DailyMed › Where a percentage is shown, it is the share of 2,288 voluntary FDA FAERS reports for Maraviroc that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Water Avens’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Water Avens side to compare — that is a limit of the record, not a statement that Water Avens has no side effects.

Everything else you take

See Every Supplement That Interacts With Maraviroc

This page covers Water Avens only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Maraviroc page lists 168 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 124 moderate · 38 minor.

From our pharmacist’s overview on the Maraviroc page

“Someone taking maraviroc (Selzentry) for HIV needs a steady blood level to keep the virus suppressed, and that level is exactly what most of the 168 supplements on this page can disturb, so this list calls for genuine care. About 121 entries share maraviroc's clearance route, the CYP3A4 enzyme, which means grapefruit can push levels up…”

Reviewed by 2 · Jul 18, 2026

Open the Maraviroc interaction page

How much people look this up

Where Water Avens and Maraviroc Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Water Avens

Steady interest

#1,235 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Maraviroc

Steady interest

#2,062 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Water Avens is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Water Avens reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Water Avens and Maraviroc records this page draws on were last updated July 11, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Water Avens

What is Water Avens?

Diarrhea and digestive upset
Sore throat and mouth irritation
Mild fever
General tonic
Astringent for minor wounds

Water avens is a traditional herb whose root has been used as an astringent for diarrhea, sore throats, and digestive complaints. There is very little modern scientific research to confirm that it works or to define a safe dose, so use it cautiously and talk with a pharmacist or doctor first.

Geum rivale · Rosaceae · Root and rhizome (occasionally aerial parts) · Dried root, tea/decoction, tincture

An interaction check asks whether these two react with each other — it does not ask whether Water Avens is a good idea for someone in your situation. Here is what our Water Avens record says about it on its own.

Water Avens: dosing

There is no established or standardized dose for water avens. Traditional use involved teas (decoctions) of the dried root or tinctures, but reliable, research-based dosing is not available.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Water Avens monograph — the full record covers uses, side effects and every documented interaction.

Read the full Water Avens monograph & all interactions

Medication

About Maraviroc

What Is Maraviroc Used For?

Brand names: Celsentri, Selzentry

Maraviroc treats a specific type of HIV-1 infection called CCR5-tropic HIV-1. It is always used alongside other antiretroviral (anti-HIV) medicines — never alone. A special test called a tropism assay must be done before starting treatment to confirm you have the right type of HIV.

Selzentry (the brand-name oral solution and tablet) is approved for adults and pediatric patients weighing at least 2 kg. Generic maraviroc tablets are approved for adults and pediatric patients aged 2 years and older weighing at least 10 kg. Neither form is recommended for patients whose HIV is classified as dual/mixed-tropic or CXCR4-tropic.

Most-Reported Side Effects for Maraviroc

From FAERS, the FDA’s public side-effect reporting system (2,288 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Virologic failure 140 reports

Viral mutation identified 128 reports

Pathogen resistance 124 reports

Anxiety 94 reports

Drug resistance 85 reports

See full Maraviroc drug information

Keep checking

Other Drugs & Water Avens

Browse every other medication we’ve checked against Water Avens — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

0Moderate

0Minor

2,829No known interaction

2,829 No interaction

No interaction 2,829 drugs checked — show the list

We also checked Water Avens against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Water Avens list.

See the full Water Avens interactions page

See every supplement checked against Maraviroc, ranked by severity

Evidence & sources

Water Avens References

The 2 sources that drive our Water Avens monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Water Avens is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

Herbs at a Glance — NIH National Center for Complementary and Integrative Health Source
Herbs and Supplements — MedlinePlus (U.S. National Library of Medicine) Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Water Avens and Maraviroc Together: Common Questions

Is it safe to take Water Avens with Maraviroc?

We do not list a known interaction between Water Avens and Maraviroc. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Does Maraviroc interact with any supplements?

Yes. Maraviroc has documented interactions with 168 supplements in our database — Water Avens is not one of them. The Maraviroc interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Water Avens monograph Uses, safety profile, and every drug interaction in one place Maraviroc drug information The full plain-English guide to this medication Maraviroc supplement interactions Every supplement checked against Maraviroc, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Maraviroc and Water Avens?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.