Drug & supplement interaction

White Mustard + Neostigmine Methylsulfate

Neostigmine Methylsulfate brand name: Bloxiverz.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between White Mustard and Neostigmine Methylsulfate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

White Mustard and Neostigmine Methylsulfate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Neostigmine Methylsulfate and White Mustard in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for White Mustard at all — not against Neostigmine Methylsulfate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

White Mustard safety at a glance

White Mustard overall Use caution Generally safe as a food, but concentrated seed products and topical applications can irritate skin and the stomach.
Pregnancy Likely Unsafe When used orally in medicinal amounts. White mustard is thought to have abortifacient and menstrual-stimulant properties. Read the full pregnancy detail
Breastfeeding Use caution Food amounts are likely fine, but medicinal amounts lack safety data, so use caution.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Neostigmine Methylsulfate and White Mustard? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests White Mustard and Neostigmine Methylsulfate May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Itching / A skin rash Additional detail

    White Mustard

    “Orally and topically, white mustard can cause allergic responses. Topically, white mustard can result in allergic contact dermatitis. Symptoms including spreading itching, red, and burning lesions have been observed on the skin of a 48-year-old woman approximately one week after she used a topical Chinese herbal medicine patch consisting of white mustard seed, licorice, ginger, corydalis, and asarabacca.”

    White Mustard · Natural Medicines adverse-effect record, reported in dermatitis.

    2 sources cited
    1. 101057. Li J, Jin HZ. Allergic contact dermatitis caused by Chinese herbal medicine, white mustard seed. J Dermatol. 2013;40(1):69-70.
    2. 101058. Vereda A, Sirvent S, Villalba M, Rodríguez R, Cuesta-Herranz J, Palomares O. Improvement of mustard (Sinapis alba) allergy diagnosis and management by linking clinical features and component-resolved approaches. J Allergy Clin Immunol. 2011;127(5):1304-7. PubMed

    Neostigmine Methylsulfate

    Listed in the ADVERSE REACTIONS section of the FDA label for Neostigmine Methylsulfate. Read the label on DailyMed ›

Effects for Neostigmine Methylsulfate come from the ADVERSE REACTIONS section of its FDA label; effects for White Mustard come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 426 voluntary FDA FAERS reports for Neostigmine Methylsulfate that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

White Mustard in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally in medicinal amounts. White mustard is thought to have abortifacient and menstrual-stimulant properties.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Neostigmine Methylsulfate

This page covers White Mustard only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Neostigmine Methylsulfate page lists 22 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Arenaria Rubra (moderate), Bacopa (moderate), Bael (moderate), Betel Nut (moderate) and Boxwood (moderate).

By severity: 21 moderate · 1 minor.

From our pharmacist’s overview on the Neostigmine Methylsulfate page

“Betel nut sits at the top of my concerns for anyone on neostigmine (Bloxiverz), a medication that boosts acetylcholine to strengthen nerve-to-muscle signaling. Nearly all 22 supplements on file work the same way the drug does, blocking the enzyme that clears acetylcholine, so stacking them can pile on cholinergic side effects like cram…”

Reviewed by 2 · Jul 18, 2026

Open the Neostigmine Methylsulfate interaction page

One more smart check

Taking White Mustard as Part of a Dietary Supplement Product? Check It for Interactions

We hold 13 real supplement products containing White Mustard, each one broken down to its full ingredient list — and combination products often carry several ingredients besides White Mustard. Even though White Mustard itself has no known interaction with Neostigmine Methylsulfate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where White Mustard and Neostigmine Methylsulfate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement White Mustard
Steady interest

#1,375 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Neostigmine Methylsulfate
Steady interest

#2,768 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every White Mustard reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The White Mustard and Neostigmine Methylsulfate records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About White Mustard

What is White Mustard?

White Mustard
  • Digestive upset
  • Joint and muscle aches (as a topical plaster)
  • Chest congestion
  • Appetite stimulation
  • Mild anti-inflammatory support

White mustard is best known as a culinary seed used to make the mustard condiment, and it has a long history in folk medicine for digestion and as a warming topical plaster. Solid human evidence for its medicinal uses is limited, so it is best enjoyed as a food while keeping medicinal claims in perspective. Talk to your pharmacist or doctor before using concentrated mustard products for health purposes.

Sinapis alba · Brassicaceae · Seeds and leaves · Whole or ground seeds, prepared mustard condiment, powder, poultice/plaster, capsules

An interaction check asks whether these two react with each other — it does not ask whether White Mustard is a good idea for someone in your situation. Here is what our White Mustard record says about it on its own.

White Mustard: dosing

There is no established standardized medicinal dose for white mustard. As a food and condiment, it is used in small culinary amounts that are generally considered safe.For any supplement or topical product, follow the directions on the label and do not exceed the recommended amount.

From our White Mustard monograph — the full record covers uses, side effects and every documented interaction.

Read the full White Mustard monograph & all interactions
Medication

About Neostigmine Methylsulfate

Most-Reported Side Effects for Neostigmine Methylsulfate

From FAERS, the FDA’s public side-effect reporting system (426 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Abdominal distension 26 reports
Hypotension 26 reports
Nausea 23 reports
Cardiac arrest 21 reports
Respiratory failure 21 reports
Keep checking

Other Drugs & White Mustard

Browse every other medication we’ve checked against White Mustard — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked White Mustard against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full White Mustard list.

See the full White Mustard interactions page
See every supplement checked against Neostigmine Methylsulfate, ranked by severity
Evidence & sources

White Mustard References

The 3 references that drive our White Mustard monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Li J, Jin HZ. Allergic contact dermatitis caused by Chinese herbal medicine, white mustard seed. J Dermatol. 2013;40(1):69-70.
  3. Vereda A, Sirvent S, Villalba M, Rodríguez R, Cuesta-Herranz J, Palomares O. Improvement of mustard (Sinapis alba) allergy diagnosis and management by linking clinical features and component-resolved approaches. J Allergy Clin Immunol. 2011;127(5):1304-7. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking White Mustard and Neostigmine Methylsulfate Together: Common Questions

Is it safe to take White Mustard with Neostigmine Methylsulfate?
We do not list a known interaction between White Mustard and Neostigmine Methylsulfate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do White Mustard and Neostigmine Methylsulfate have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Neostigmine Methylsulfate interact with any supplements?
Yes. Neostigmine Methylsulfate has documented interactions with 22 supplements in our database — White Mustard is not one of them. The Neostigmine Methylsulfate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

White Mustard monograph Uses, safety profile, and every drug interaction in one place Neostigmine Methylsulfate supplement interactions Every supplement checked against Neostigmine Methylsulfate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Neostigmine Methylsulfate and White Mustard?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.