Drug & supplement interaction

Yarrow + Meclofenamate

Meclofenamate brand name: Meclomen.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Yarrow and Meclofenamate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Meclofenamate states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Yarrow and Meclofenamate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Meclofenamate and Yarrow in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Yarrow safety at a glance

Yarrow overall Use caution Often used short-term, but human safety data are limited and allergic reactions can occur.
Pregnancy Likely Unsafe When used orally; yarrow is believed to be an abortifacient and affect the menstrual cycle. Read the full pregnancy detail
Breastfeeding Avoid Not enough safety information, so it is best avoided while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Meclofenamate and Yarrow? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Meclofenamate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Meclofenamate is filed under 5 classifications — including nonsteroidal anti-inflammatory drugs (nsaids), organic anion transporter 3 (oat3) substrates, organic anion transporter 1 (oat1) substrates. Yarrow has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Meclofenamate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Yarrow Does Interact With Other Medications

Yarrow has 1 moderate known drug interaction in our database — Meclofenamate isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Yarrow

Covers the 2,830 medications we’ve checked against Yarrow. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Yarrow and Meclofenamate May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Hives Worth acting on Additional detail

    Yarrow

    “Topically, yarrow can cause atopic or allergic dermatitis or urticaria due to its sesquiterpene lactone content. Yarrow has also been reported to cause phototoxic and photo-allergic dermatitis and airborne contact dermatitis.

    Intravaginally, aggravated facial acne was reported by 1 of 40 patients in a clinical trial.”

    Yarrow · Natural Medicines adverse-effect record, reported in acne.

    4 sources cited
    1. 52558. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
    2. 68385. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
    3. 77007. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
    4. 105360. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed

    “Topically, yarrow can cause atopic or allergic dermatitis or urticaria due to its sesquiterpene lactone content. It has also been reported to cause phototoxic and photo-allergic dermatitis and airborne contact dermatitis. In one 44-year-old female, handling yarrow flowers resulted in rhinitis and asthma.”

    Yarrow · Natural Medicines adverse-effect record, reported in asthma.

    4 sources cited
    1. 52558. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
    2. 68385. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
    3. 77007. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
    4. 96911. Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.

    Meclofenamate

    Listed in the ADVERSE REACTIONS section of the FDA label for Meclofenamate. Read the label on DailyMed ›

  • Itching Additional detail

    Yarrow

    “Intravaginally, aggravated vaginal pruritus and dryness were reported by 1 of 40 patients in a clinical trial.”

    Yarrow · Natural Medicines adverse-effect record, reported in pruritus.

    1 source cited
    1. 105360. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed

    Meclofenamate

    Listed in the ADVERSE REACTIONS section of the FDA label for Meclofenamate. Read the label on DailyMed ›

  • A skin rash Additional detail

    Yarrow

    “Orally and intravaginally, yarrow seems to be well tolerated.

    Most Common Adverse Effects:

    Topically: Dermatitis.”

    Yarrow · Natural Medicines adverse-effect record, reported in dermatitis.

    Meclofenamate

    Listed in the ADVERSE REACTIONS section of the FDA label for Meclofenamate. Read the label on DailyMed ›

Reported for Yarrow but not commonly for Meclofenamate: a stuffy or runny nose, wheezing and acne.

Effects for Meclofenamate come from the ADVERSE REACTIONS section of its FDA label; effects for Yarrow come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Yarrow in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally; yarrow is believed to be an abortifacient and affect the menstrual cycle.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Meclofenamate Products Have a Food Rule — Yarrow Should Not Break It

At least one FDA label for a product containing Meclofenamate says to take it with food. If you take Yarrow on an empty stomach out of habit, keep them separate — and take Meclofenamate with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Meclofenamate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

If gastrointestinal complaints occur (see WARNINGS and PRECAUTIONS ), meclofenamate sodium may be administered with meals or with milk (see CLINICAL PHARMACOLOGY for a description of food effects).

From the Dosage and Administration section of the FDA label we read for Meclofenamate — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Overlapping uses

What Meclofenamate Is Prescribed For, and What Yarrow Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Meclofenamate is a prescription medicine with approved uses on its FDA label. Yarrow is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Meclofenamate is prescribed for: Meclofenamate sodium capsules are used in adults to relieve mild to moderate pain, reduce fever, and treat the signs and symptoms of rheumatoid arthritis, osteoarthritis, juvenile arthritis, and ankylosing spondylitis (a type of spinal arthritis). They are also used for acute painful shoulder, acute gouty arthritis, primary dysmenorrhea (painful periods), and idiopathic heavy menstrual bleeding. This medication is not recommended for use in children, as adequate safety and effectiveness studies have not been carried out in that age group.

Yarrow has been studied for:

  • Dysmenorrhea studied, not established Yarrow has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Yarrow for dysmenorrhea

    It is unclear of oral yarrow tea is beneficial for improving symptoms of dysmenorrhea.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Meclofenamate on your own; if you are taking Yarrow for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Meclofenamate

This page covers Yarrow only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Meclofenamate page lists 32 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Siberian Cocklebur (major) and Wine (major).

By severity: 5 major · 16 moderate · 11 minor.

From our pharmacist’s overview on the Meclofenamate page

“Meclofenamate (Meclomen) is a prescription NSAID for pain and arthritis, a class of drug that is already hard on the stomach and kidneys, so this list deserves real care rather than a quick skim. Five of its 32 supplement and herbal interactions rate major, clustered around two dangers: alcohol (beer and wine both raise the risk of sto…”

Reviewed by 2 · Jul 18, 2026

Open the Meclofenamate interaction page

One more smart check

Taking Yarrow as Part of a Dietary Supplement Product? Check It for Interactions

We hold 600 real supplement products containing Yarrow, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Yarrow. Even though Yarrow itself has no known interaction with Meclofenamate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Yarrow and Meclofenamate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Yarrow
Top 25%

#249 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Meclofenamate
Top half

#979 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Yarrow reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Yarrow and Meclofenamate records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Yarrow

What is Yarrow?

Yarrow
  • Wounds and minor bleeding
  • Digestive upset and cramping
  • Colds, flu, and fever
  • Skin conditions
  • Menstrual discomfort

Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used short-term, and people who are pregnant, breastfeeding, or allergic to ragweed and related plants should avoid it.

Achillea millefolium · Asteraceae · Aerial parts (leaves, flowers, and stems) and essential oil · Tea, tincture, capsules, dried herb, topical creams or ointments, and essential oil

An interaction check asks whether these two react with each other — it does not ask whether Yarrow is a good idea for someone in your situation. Here is what our Yarrow record says about it on its own.

Yarrow: dosing

There is no official, standardized dose for yarrow. Traditional use includes teas made from the dried herb, tinctures, and capsules, as well as creams applied to the skin.Because product strengths vary widely, the safest approach is to follow the directions on the product label and not exceed them. Yarrow is intended for short-term use, not long-term daily use.

From our Yarrow monograph — the full record covers uses, side effects and every documented interaction.

Read the full Yarrow monograph & all interactions
Medication

About Meclofenamate

What Is Meclofenamate Used For?

Brand name: Meclomen

Meclofenamate sodium capsules are used in adults to relieve mild to moderate pain, reduce fever, and treat the signs and symptoms of rheumatoid arthritis, osteoarthritis, juvenile arthritis, and ankylosing spondylitis (a type of spinal arthritis). They are also used for acute painful shoulder, acute gouty arthritis, primary dysmenorrhea (painful periods), and idiopathic heavy menstrual bleeding.

This medication is not recommended for use in children, as adequate safety and effectiveness studies have not been carried out in that age group.

See full Meclofenamate drug information
Keep checking

Other Drugs & Yarrow

Browse every other medication we’ve checked against Yarrow — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
1Moderate
0Minor
2,828No known interaction
Moderate

1 interaction

No interaction 2,828 drugs checked — show the list
Evidence & sources

Yarrow References

The 8 references that drive our Yarrow monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
  3. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
  4. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
  5. Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.
  6. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
  7. de Souza P, Crestani S, da Silva Rde C, et al. Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae). J Ethnopharmacol. 2013 Aug 26;149(1):157-61. PubMed
  8. Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani M. Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. Eur J Oncol Nurs. 2015;19(3):207- PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Yarrow and Meclofenamate Together: Common Questions

Is it safe to take Yarrow with Meclofenamate?
We do not list a known interaction between Yarrow and Meclofenamate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Yarrow and Meclofenamate have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Yarrow and Meclofenamate at the same time of day?
At least one FDA label for a product containing Meclofenamate says to take it with food. If you take Yarrow on an empty stomach out of habit, keep them separate and take Meclofenamate with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Meclofenamate products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Are Yarrow and Meclofenamate used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Yarrow in each. That is a conversation for your prescriber, especially if Meclofenamate is being adjusted to a target.
How was the Yarrow and Meclofenamate combination checked?
Interactions in our licensed database are recorded against drug classes. Meclofenamate is filed under 5 classifications, and Yarrow has documented interactions with 1 drug class — none of Meclofenamate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Yarrow interact with any other medications?
Yes. Yarrow has 1 documented drug interaction in our database — Meclofenamate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Meclofenamate interact with any supplements?
Yes. Meclofenamate has documented interactions with 32 supplements in our database — Yarrow is not one of them. The Meclofenamate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Meclofenamate and Yarrow?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.