Yellow Toadflax + Denileukin
Denileukin brand name: Ontak.
We found no known interaction between Yellow Toadflax and Denileukin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Yellow Toadflax and Denileukin
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Denileukin and Yellow Toadflax in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Yellow Toadflax at all — not against Denileukin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Yellow Toadflax safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Denileukin
This page covers Yellow Toadflax only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Denileukin page lists 17 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).
By severity: 1 major · 7 moderate · 9 minor.
From our pharmacist’s overview on the Denileukin page
“Activated charcoal is the interaction I would settle first for anyone receiving denileukin (Ontak), a cancer treatment for cutaneous T-cell lymphoma. It carries the only major rating among the 17 supplements on file, and unlike the rest it can lower drug exposure no matter how the medicine is given, because it traps compounds that reci…”
Reviewed by 2 · Jul 18, 2026
Where Yellow Toadflax and Denileukin Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,248 of 1,452 supplements looked up here in the last 7 days
#2,209 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Yellow Toadflax is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Yellow Toadflax reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Yellow Toadflax and Denileukin records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Yellow Toadflax
What is Yellow Toadflax?
- Hemorrhoids and skin irritation
- Mild constipation
- Fluid retention (as a folk diuretic)
- Liver and gallbladder complaints (traditional)
- Minor wounds and inflammation (topical)
Yellow toadflax is a traditional folk remedy used mostly for hemorrhoids, skin problems, and as a mild laxative or diuretic, but there is very little modern human research to confirm any of these uses. Because its safety has not been well studied, it is best used cautiously, avoided in pregnancy and breastfeeding, and discussed with a pharmacist or doctor first.
Linaria vulgaris · Plantaginaceae · Aerial parts (flowering tops, leaves, and stems) · Tea, tincture, dried herb, ointment or salve, poultice
An interaction check asks whether these two react with each other — it does not ask whether Yellow Toadflax is a good idea for someone in your situation. Here is what our Yellow Toadflax record says about it on its own.
Yellow Toadflax: dosing
There is no well-established or standardized dose for yellow toadflax. Traditional preparations vary widely, and modern guidelines for safe amounts do not exist.If you choose to use a commercial product, follow the directions on the label and do not exceed them.
From our Yellow Toadflax monograph — the full record covers uses, side effects and every documented interaction.
About Denileukin Diftitox Injection
What Is Denileukin Diftitox Injection Used For?
Brand name: Ontak
LYMPHIR is approved for adults with cutaneous T-cell lymphoma (CTCL) — a cancer that starts in certain white blood cells and mainly affects the skin — specifically Stage I through III disease that has relapsed (come back) or is refractory (no longer responding) after at least one prior systemic (whole-body) treatment.
It is not a first-line therapy. It's used when earlier treatments have already been tried and the cancer has continued to progress.
Other Drugs & Yellow Toadflax
Browse every other medication we’ve checked against Yellow Toadflax — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Yellow Toadflax against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Amlodipine ›
- Levothyroxine ›
- Methylphenidate ›
- Warfarin ›
- Abemaciclib ›
- Ivermectin ›
- Testosterone ›
- Sertraline ›
- Acetaminophen ›
- Losartan Potassium ›
- Aspirin ›
- Rosuvastatin ›
- Metoprolol ›
- Escitalopram ›
- Clopidogrel ›
- Rivaroxaban ›
- Atorvastatin ›
- Methamphetamine ›
- Tirzepatide ›
- Isotretinoin ›
- Warfarin Sodium ›
- Ibuprofen ›
- Docusate ›
- Sumatriptan ›
- Valacyclovir ›
- Amlodipine Besylate ›
- Tadalafil ›
- Hydroxyurea ›
- Prednisone ›
- Semaglutide ›
- Metformin ›
- Lisdexamfetamine ›
- Amitriptyline ›
- Propranolol ›
- Amphetamine ›
- Methotrexate ›
- Amoxicillin ›
- Lisinopril ›
- Levothyroxine, Liothyronine ›
- Bupropion ›
- Fluoxetine ›
- Bendamustine ›
- Doxycycline ›
- Azithromycin ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Acyclovir ›
- Gabapentin ›
- Naproxen ›
- Quetiapine ›
- Clonazepam ›
- Buspirone ›
- Omeprazole ›
- Duloxetine ›
- Acetaminophen, Codeine ›
- Letrozole ›
- Citalopram ›
- Methylene Blue ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Yellow Toadflax list.
Yellow Toadflax References
The 1 sources that drive our Yellow Toadflax monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Yellow Toadflax is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- Dietary and Herbal Supplements — NIH NCCIH Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Yellow Toadflax and Denileukin Together: Common Questions
Is it safe to take Yellow Toadflax with Denileukin?
Does Denileukin interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.